Primary Care

Obesity

Latest AI and machine learning research in obesity for healthcare professionals.

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Machine learning combining FIT with up to 1,025 clinical variables: limited referral reduction but potential for faster diagnosis

Background The faecal immunochemical test (FIT) is central to triaging symptomatic patients with suspected colorectal cancer (CRC) in UK primary care, yet only about one in eleven patients above the NICE 10 ug/g threshold have CRC. Existing prediction models attempting to improve on FIT have relied on conventional statistics and limited predictors. Methods GP-requested FITs with linked data (Jan 2...

Causal-Adversarial Probing of Clinical Covariates for Prostate MRI Grading

Deep learning models for prostate MRI-based cancer grading may encode clinical covariates that either reflect useful disease-related signal or non-generalising shortcut information, but their role is usually assumed. We propose a causal-reasoning framework for probing covariate dependence in MRI-based International Society of Urological Pathology (ISUP) Grade Group prediction. Rather than treating...

Jul 16 2026 2607.14720v1
Life-Stage Heterogeneity in the Mental Health Treatment Gap: An Unsupervised Machine Learning Profiling of Symptomatic US Adults

Abstract Background Despite a rising global psychiatric burden, a treatment gap persists where the majority of symptomatic individuals remain unmedica...

Comorbidity Exposure-Window Definitions and Multidimensional Disparities in Long COVID Risk: Evidence from a U.S. National Cohort (2020-2024)

Long COVID (LC) affects millions of individuals worldwide, particularly those with preexisting comorbidities. However, whether these comorbidities sho...

Optimally Predicting Mortality in Patients with Abdominal Aortic Aneurysms

Abdominal aortic aneurysm (AAA) patients in the ICU represent a heterogeneous, high-risk population with mortality risk evolving across distinct clini...

Data-driven Prediction of Fifteen-Year All-Cause Mortality among 2.3 Million Individuals in the VA

We present a data-driven framework to predict 15-year all-cause mortality using outpatient administrative records for 2.3 million Veterans in the larg...

Learning the shared structure of human health across diseases, modalities, and time

Human disease risk emerges from the shared influences of genetics, environment, lifestyle, and concurrent diseases over time, resulting in recurring p...

DeepPySR -- A Symbolic Regression Framework with Dynamic Pruning, Pareto Selection, and Hierarchical Composition for Real-World Scientific Discovery

Symbolic regression (SR) discovers analytical equations from data, yielding glass-box models with directly interpretable formulas, unlike black-box me...

Jul 9 2026 2607.08150v1
Emergency Department Presenting Concerns Among Admissions With Hypercapnia: A Retrospective NLP Study of MIMIC-IV

Background Hypercapnia may indicate a primary ventilatory syndrome, a complication of another illness, or an epiphenomenon of severe disease. The pres...

Prediction of post-operative delirium with machine learning in abdominal surgery with comorbidity indices and laboratory values

Background: Postoperative delirium (POD) is a complication associated with most types of surgery, and is associated with a number of detrimental effec...

Accelerometry-Derived Digital Biomarkers for Cardiometabolic Risk: A Population-Representative Tabular Benchmark with Uncertainty Quantification

Structured tabular data dominates clinical medicine, yet existing benchmarks fail to reflect real-world properties like complex survey sampling, demog...

Jun 29 2026 2606.30702v1
Healthy-to-Stroke Translation of EEG-Based BMIs: EEG Characterization and Reinforcement Learning-Based Decoder Evaluation

Purpose: EEG-based brain-machine interfaces (BMIs) may support assistive technologies for individuals with stroke-related motor impairment by translat...

Multi-Omics Clustering Differentiates the Total and Intact HIV Reservoirs and Related Host Immune Mechanisms

HIV reservoirs are heterogeneous across individuals, yet host determinants of this variability remain unclear. Applying multi-omics clustering to 1,23...

A next-generation electronic frailty index leveraging deep learning on unstructured health records extends risk prediction across the full frailty spectrum

Background: Existing electronic frailty indices (eFI) are typically based on structured data and designed for older adults. We developed an eFI that i...

Beyond Visual Forensics: Auditing Multimodal Robustness for Synthetic Medical Image Detection

With the rapid adoption of generative AI, synthetic medical images pose growing risks, including diagnostic deception and insurance fraud. Although pr...

Jun 24 2026 2606.25375v1
Cumulative Metabolic Exposure to Hyperglycemia and Risk of Cardiovascular and Limb Events in Peripheral Artery Disease

Background: Although diabetes is a potent risk factor for the development of peripheral artery disease (PAD), the effect of cumulative metabolic expos...

Explainable AI for Mental Health Prediction in Drug-Affected Populations with Dragonfly Algorithm and GAN Oversampling

Mental illnesses among drug users are an increasing international issue, particularly in regions where early detection cannot be easily undertaken. Th...

Jun 22 2026 2606.22780v1
Context-Aware Optimization of Follow-Up Intervals for Type 2 Diabetes Care Using Markov Decision Processes

Chronic disease management relies on regular patient-provider interactions to follow-up on disease progression and control. For Type 2 Diabetes (T2D),...

Jun 17 2026 2606.19092v1
A Machine-Learned Comorbidity Index

Traditional comorbidity scores (e.g., Charlson and Elixhauser) are widely used for risk adjustment and patient stratification, but they have two key l...

Jun 16 2026 2606.17450v1
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