Oncology/Hematology

Latest AI and machine learning research in oncology/hematology for healthcare professionals.

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Showing 2081-2100 of 18,705 articles

Genomic Determinants of Response to Alpelisib Plus Fulvestrant in the SOLAR-1 Trial.

BACKGROUND: Approximately 40% of patients with hormone receptor-positive (HR+), human epidermal growth factor receptor 2-negative (HER2-), advanced breast cancer (ABC) have PIK3CA alterations, which contributes to endocrine therapy resistance. Alpelisib, an α-selective phosphatidylinositol 3-kinase inhibitor and degrader, given in combination with fulvestrant, is approved for the treatment of PIK3...

Apr 10 2026 41967638

Regulatory B cells and SIVA1-LAG3 immune suppression predict poor prognosis in prostate cancer.

Prostate cancer (PCa) is among the most prevalent malignancies affecting men globally. The immunosuppressive characteristics of the tumor microenvironment significantly hinder the effectiveness of immunotherapeutic strategies. B cells have a dual role in immune responses, with regulatory B cells (Bregs) promoting immune tolerance through the secretion of immunosuppressive cytokines, facilitating t...

Apr 10 2026 41960835
Challenges and Controversies in the Diagnosis and Management of Thymic Epithelial Tumors from the Thymic Tumor Subcommittee of the International Association for the Study of Lung Cancer Rare Tumors Committee.

Thymic epithelial tumors (TETs), comprising thymomas, thymic carcinomas, and thymic neuroendocrine neoplasms, are rare prevascular (anterior) mediasti...

Apr 10 2026 41961041
Quantitative CT Perfusion as a prognostic biomarker for chemotherapy response in patients with pancreatic ductal adenocarcinoma.

BACKGROUND: Response evaluation of pancreatic ductal adenocarcinoma (PDAC) with routine contrast-enhanced CT (CECT) using RECIST is currently inadequa...

Apr 10 2026 41961316
Multigated DNA Cascade Amplifier for Ultrasensitive Spatiotemporal Imaging of PLS3 mRNA at the Single-Cell Level for Early Detection of Breast Cancer Metastasis.

Early detection of small metastatic foci is crucial for improving breast cancer patient survival. Plastin-3 (PLS3) has emerged as a key biomarker in b...

Apr 10 2026 41961955
AI-enabled psychometric and psychophysiological assessment in psychiatric comorbidity of oncology patients: A systematic review.

BACKGROUND: The state of psychological distress, including depression and anxiety, is very common among patients with cancer. Common screening tools a...

Apr 10 2026 41961981
Ultrasound Radiomics for Hashimoto's Thyroiditis: State of the Art and Future Perspectives.

Ultrasound radiomics is gradually emerging as a powerful tool for improving the diagnosis and management of Hashimoto's thyroiditis (HT), effectively ...

Apr 10 2026 41963245
How Hospice and Palliative Care Are Portrayed in Artificial Intelligence-Generated Images: A Content Analysis.

BACKGROUND: AI-generated images can support or impede health communication efforts and influence perceptions of health-related topics, making it impor...

Apr 10 2026 41963247
Mechanized precision: the rise of robotic systems in spinal surgery.

BACKGROUND: Robot-assisted spinal surgery has rapidly evolved into a transformative innovation. Initially developed for pedicle screw placement, curre...

Apr 10 2026 41963617
Deepath-SCC: a deep learning model for accurate tissue origin identification in squamous cell carcinoma.

Squamous cell carcinoma (SCC) is a common malignancy that arises in diverse organs and often exhibits overlapping histological and immunophenotypic fe...

Apr 10 2026 41963625
Deep learning-based pathomics signature predicts prognosis and treatment response in gastric cancer: a multicenter retrospective study.

The existing TNM staging system provides insufficient prognostic information in gastric cancer (GC) patients. This study aims to establish a pathomics...

Apr 10 2026 41957258
Clinical Translatable and Transparency of Neural Network for Blood-Based Personalized Cancer Risk.

OBJECTIVE: To support cancer screening and identify precancerous conditions, such as atypical hyperplasia, to improve cure rates and reduce mortality,...

Apr 9 2026 42170495
Comprehensive Assessment of Artificial Intelligence as a Stand-alone tool for Cervical Cancer Screening Using a 50% Negative Cutoff Value.

PURPOSE: An emerging application of artificial intelligence (AI) in cervical cytology is its use as an independent screener for triaging cases that do...

Apr 9 2026 41966523
Efferocytosis-related biomarkers and immune infiltration in pancreatic ductal adenocarcinoma based on single-cell sequencing and machine learning: a comprehensive bioinformatics analysis and experimental validation.

BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) is a highly invasive and lethal malignancy, with its complex tumor microenvironment (TME) severely...

Apr 9 2026 41966742
OncoEducate: A Pilot Study of Generative AI to Enhance Patient-Clinician Communication in Genitourinary Cancer Care.

OncoEducate is a clinician-supervised generative artificial intelligence (AI) application designed to deliver standardized, regimen-level, plain-langu...

Apr 9 2026 41967073
Cost-effectiveness of an artificial intelligence predictive model for guiding androgen deprivation therapy in intermediate-risk prostate cancer.

The ArteraAI Prostate Test (ArteraAI Inc.) is the first predictive biomarker for benefit of adding short-term androgen deprivation therapy (ADT) to ra...

Apr 9 2026 41967115
Predicting hepatocellular carcinoma in people with hepatitis B: a comparison between Cox proportional hazard and machine learning models.

BACKGROUND AND AIM: Hepatocellular carcinoma (HCC) is a leading cause of cancer-related death worldwide, with chronic hepatitis B virus (HBV) infectio...

Apr 9 2026 41962179
Artificial intelligence for metabolic dysfunction-associated steatotic liver disease diagnosis: A systematic review.

Metabolic dysfunction-associated steatotic liver disease (MASLD) poses significant diagnostic challenges. We conducted a systematic review of artifici...

Apr 9 2026 41962452
Dual-model deep learning for Alzheimer's prognostication.

Disease-modifying therapies for Alzheimer's disease demand precise timing decisions, yet current predictive models require longitudinal clinical obser...

Apr 9 2026 41962454
Vocal Age Gap as a Noninvasive Biomarker for Early Detection of Laryngeal Cancer Using Deep Learning.

OBJECTIVES: Early vocal changes such as hoarseness or voice fatigue are common and often attributed to normal aging or benign conditions, which can de...

Apr 9 2026 41963165
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