Oncology/Hematology

Latest AI and machine learning research in oncology/hematology for healthcare professionals.

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Higher Diagnostic Accuracy of an AI Model for Colposcopy Compared With Conventional and Digital Colposcopic Evaluation.

OBJECTIVE: Colposcopy involves subjective visual assessment of cervical features that may indicate cervical dysplasia. Pattern recognition during colposcopy could be enhanced by artificial intelligence (AI). Using colposcopy images with precisely mapped multiple biopsy sites and corresponding histologic diagnoses, we developed an AI model, Cervix-AID-Net, to classify colposcopy images into low-gra...

Apr 1 2026 41589749

Assessment of the risk of bacteremia in patients with hematologic malignancies in the emergency department: A comparative study between logistic regression and machine learning algorithms.

OBJECTIVE: To stratify the risk of bacteremia at the time of emergency department (ED) admission in patients with hematologic malignancies. To this end, we compared the performance of unsupervised and supervised machine learning algorithms with the classical multivariable logistic regression model. METHODS: We conducted a multicenter, international, retrospective cohort study including consecutive...

Apr 1 2026 41880164
Interpretable LightGBM model with SHAP analysis predicts non-excellent response to initial radioiodine therapy in differentiated thyroid carcinoma.

PURPOSE: To identify independent determinants influencing therapeutic outcomes of initial radioactive iodine (1 3 1I) therapy in differentiated thyroi...

Apr 1 2026 41889257
A deep learning model for histopathological diagnosis of actinic keratosis: a diagnostic case control accuracy study.

BACKGROUND: Actinic keratosis (AK) is a precancerous skin lesion with the potential to progress into squamous cell carcinoma (SCC), with an overall pr...

Apr 1 2026 41891835
Integrative Analysis Combining Machine Learning and Functional Experiments Uncovers ISG15 As a Key Determinant of Cisplatin Resistance in Gastric Cancer.

BACKGROUND/AIM: Cisplatin resistance remains a major obstacle in advanced gastric cancer (GC). This study aimed to identify key molecular determinants...

Apr 1 2026 41895760
Usefulness of Artificial Intelligence for Surgical Support in Robot-assisted Distal Pancreatectomy: A Preliminary Case Report.

BACKGROUND/AIM: The incidence of postoperative complications in minimally-invasive surgery for pancreatic disease remains a concern. The application o...

Apr 1 2026 41895782
Single-Cell Transcriptomic Analysis of Chemotherapy-Induced Changes in Osteosarcoma With a Pyroptosis-Related Gene-Based Prognostic Model.

Osteosarcoma, the most common primary malignant bone tumour, presents significant treatment challenges due to its complex tumour microenvironment and ...

Apr 1 2026 41896410
Head radiotherapy positioning guidance system based on feature recognition and automatic annotation: Clinical validation and error analysis.

BACKGROUND: Positioning accuracy in radiotherapy is critical for treatment outcomes, especially in head tumor radiotherapy, where the target area is s...

Apr 1 2026 41904706
Deep Learning for Automated Tumor Segmentation of Rectal Cancer on T2-Weighted Magnetic Resonance Images.

PURPOSE: To develop a deep learning (DL)-based automated segmentation model for rectal cancer on T2-weighted (T2W) magnetic resonance (MR) images. MAT...

Apr 1 2026 41914320
Automated identification of radiotherapy treatment sites from unstructured physician notes.

PURPOSE: Ambiguous or incomplete documentation is a recurrent bottleneck in radiation oncology workflows, leading to inefficiencies in communication a...

Apr 1 2026 41914356
Arrhythmias and cardiac devices management in oncology patients.

Cardiac arrhythmia is increasingly encountered in patients with cancer, not only as a result of shared risk factors but also as a direct consequence o...

Mar 31 2026 41933629
A 3D morphogenetic blueprint for metastatic outgrowth in breast cancer.

The tissue-level processes underpinning metastatic outgrowth remain unclear. We combined single-cell RNA sequencing, spatial transcriptomics, and AI-s...

Mar 31 2026 41923644
MorphoNet: Morphological sub-region-based structure learning for WSI analysis.

Representation learning of Whole slide image (WSI) is fundamental to computational pathology, enabling tasks such as tumor subtyping, survival predict...

Mar 31 2026 41965167
A metabolite-augmented FIB-4 machine learning panel achieves superior liver fibrosis staging in chronic liver disease.

Accurate, non-invasive liver fibrosis detection is essential for chronic liver disease management, particularly with rising metabolic dysfunction-asso...

Mar 31 2026 41923623
A high-speed attention network for MHC-bound peptide identification and 3D modeling.

We developed SwiftMHC, an ultra-fast and accurate structure-based framework for peptide-MHC (pMHC) modeling and binding affinity prediction. Using tas...

Mar 31 2026 41923631
Explainable Machine Learning for Performance Assessment of Fiber-Nanoparticle Concrete in High-Altitude Cold Environments.

The construction of concrete structures in high-altitude cold regions faces unique challenges, including intense radiation, low atmospheric pressure, ...

Mar 31 2026 41913714
Neurosurgical Application of Artificial Intelligence in Pediatric Neuro-Oncology.

Pediatric neuro-oncology is a critical field of neurosurgery, representing the leading cause of disease-related mortality in children. Despite its rar...

Mar 31 2026 41913971
Short-chain fatty acid-producing microbes differentiate non-infectious and infectious neutropenic fever in leukemia.

UNLABELLED: Neutropenic fever (NF) is often the first sign of infection in patients with hematologic malignancies, but its cause is frequently unknown...

Mar 31 2026 41914747
Testosterone-Sparing Treatment Strategies for Biochemically Recurrent Prostate Cancer After Radical Prostatectomy.

PURPOSE OF REVIEW: Biochemical recurrence (BCR) after radical prostatectomy occurs in up to one-third of patients and increases the risk of metastasis...

Mar 31 2026 41915319
AI-assessed sarcopenia as an independent predictor of neoadjuvant chemotherapy outcomes in muscle-invasive bladder cancer.

PURPOSE: Sarcopenia has already been widely investigated as a potential indicator of negative outcomes in oncology patients. Our aim was to evaluate t...

Mar 31 2026 41915371
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