Oncology/Hematology

Latest AI and machine learning research in oncology/hematology for healthcare professionals.

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Showing 2701-2720 of 18,705 articles

Artificial intelligence-based pathological model for pan-cancer lymph node metastasis detection: a multicentre diagnostic study with retrospective and prospective validation.

BACKGROUND: Accurate detection of lymph node metastasis is crucial for precise tumour staging and treatment planning. Conventional pathological examination can overlook lymph node micrometastasis, resulting in underdiagnosis and suboptimal clinical outcomes. This study aimed to develop a pan-cancer artificial intelligence diagnostic model (PanCAM) for detecting lymph node metastasis across cancer ...

Mar 5 2026 41792018

Pseudohypoxia and Family History Are Key Predictors of Severe Outcomes in Hereditary Pheochromocytoma and Paraganglioma Syndromes.

OBJECTIVE: Pheochromocytoma and paraganglioma (PPGL) have high genetic predisposition rates. In this multicenter study, we aimed to identify risk-modulating factors for disease development and aggressiveness in patients carrying pathogenic variants (PPGLgPV) related to PPGL genes. METHODS: Observational prospective study including patients with PPGL, family history of PPGL or suspected PPGL-relate...

Mar 5 2026 41783997
Differentiation of Benign and Malignant Cervical Lymph Nodes Using a Multi-Modal Ultrasound-Based Machine Learning Model with SHAP Interpretability.

OBJECTIVES: To evaluate the diagnostic value of a machine learning (ML) model based on multi-modal ultrasound features in differentiating benign from ...

Mar 5 2026 41784164
Intelligent model for stratification of acute radiation syndrome severity in humans.

PURPOSE: The aim of this study was to develop and compare two intelligent model for stratifying the severity of acute radiation syndrome (ARS) in huma...

Mar 5 2026 41784608
Spatial analysis of air pollution and cancer prevalence in Texas: a machine learning approach using satellite remote sensing data.

Cancer prevalence in the world has been attributed to exposure to air pollutants. However, spatial analyses utilizing remote sensing data have been li...

Mar 5 2026 41784679
Decoding the Glioblastoma Microenvironment: AI-Driven Analysis of Cellular MRI Signatures for Targeted Therapy.

Glioblastoma (GB), the most aggressive primary brain tumor, is characterized by profound inter- and intratumoral heterogeneity and a highly immunosupp...

Mar 5 2026 41784819
Artificial intelligence-enabled ultrasound diagnosis and stratification of follicular thyroid neoplasms: a multi-center study.

Preoperatively distinguishing follicular thyroid carcinoma (FTC) from follicular thyroid adenoma (FTA) remains a significant clinical challenge. Curre...

Mar 5 2026 41781694
Cost-effectiveness analysis of artificial intelligence-assisted risk stratification of indeterminate pulmonary nodules.

BACKGROUND: Artificial intelligence-based radiomic approaches have been shown to accurately evaluate indeterminate pulmonary nodules. With the expansi...

Mar 5 2026 41785281
Reflectance confocal microscopy in the management of lentigo maligna and lentigo maligna melanoma: a systematic review.

BACKGROUND: Lentigo maligna (LM) and lentigo maligna melanoma (LMM) are difficult to manage because of their subclinical extension and ill-defined mar...

Mar 4 2026 41908627
CAR T-cells in hematologic malignancies: Advances, challenges, and future directions.

Chimeric antigen receptor (CAR) T-cell therapy has transformed the management of hematologic malignancies, achieving high remission rates in relapsed ...

Mar 4 2026 41940327
Challenges and advances in drug resistance and tolerance in cancer.

Therapeutic resistance remains the principal barrier to durable clinical benefit in oncology, particularly in oncogene-driven malignancies and immune-...

Mar 4 2026 41776655
Impact of Deep Learning-Based Time-of-Flight PET Images of Small Tumors Using a Human Anatomic Phantom.

Time-of-flight (ToF) in PET improves image quality by enhancing the signal-to-noise ratio, and recent deep learning (DL)-based ToF (DL-ToF) methods fu...

Mar 4 2026 41188046
Risk factors for postoperative recurrence of sinonasal inverted papilloma: a retrospective analysis of 171 cases.

BACKGROUND: Sinonasal inverted papilloma(SNIP) is a benign tumor with a potential of malignant transformation but has a certain recurrence. OBJECTIVES...

Mar 4 2026 41778303
Artificial Intelligence-Enhanced Optimization of Wireless Breath Sensor Arrays for Detection of Lung Cancer Using Fuzzy Logic-Guided Genetic Algorithm and Multimodal Machine Learning.

Early detection of lung cancer remains critical for improving patient survival, yet current imaging-based screening methods are costly, invasive, and ...

Mar 4 2026 41778589
Bytes to Blood-Artificial Intelligence in the Management of Leukemia: A 2025 Update.

As artificial intelligence (AI) has been proposed to aid in the clinical management of leukemia, we sought to summarize the most relevant, current lit...

Mar 4 2026 41779677
Deep learning linking mechanistic models to single-cell transcriptomics data reveals transcriptional bursting in response to DNA damage.

Cells must adopt flexible regulatory strategies to make decisions regarding their fate, including differentiation, apoptosis, or survival in the face ...

Mar 4 2026 41779826
Digital breast tomosynthesis and reading with artificial intelligence.

Digital breast tomosynthesis (DBT) increases sensitivity and specificity compared to digital mammography (DM) in the early detection of breast cancer....

Mar 4 2026 41780548
Machine Learning-Based Preoperative Predicting TERT Promoter Mutation and EGFR Gene Amplification Phenotype in IDH Wild-Type Glioblastoma Using Advanced MR Habitat Imaging.

BACKGROUND AND PURPOSE: The telomerase reverse transcriptase (TERT) gene promoter mutation is a crucial factor for identifying an isocitrate dehydroge...

Mar 4 2026 41781177
Magnification-independent breast cancer diagnosis using a GWO-enhanced vision transformer with multi-stage stain normalization.

Breast cancer diagnosis from histopathological images remains a critical yet challenging task due to staining variability, magnification differences, ...

Mar 4 2026 41781597
Cell-free chromatin state tracing reveals disease origin and therapy responses.

Cell-free DNA in blood originates from fragmented chromatin released by dying cells from both healthy and diseased tissues1,2. These fragments carry r...

Mar 4 2026 41781618
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