Oncology/Hematology

Angioimmunoblastic T-cell lymphoma with lymphomatous effusion: Diagnostic challenges and cytology-based approaches.

Angioimmunoblastic T-cell lymphoma (AITL) is an aggressive peripheral T-cell lymphoma with a poor prognosis. Lymphomatous serous effusion, defined as the presence of malignant lymphoma cells in the pleural, pericardial, or peritoneal fluid, is a rare but clinically important manifestation, particularly when a lymph node biopsy is difficult or delayed. We performed a narrative review of case report...

Advances in the pharmacology and mechanism of anti-skin aging in Tonifying Traditional Chinese Medicines.

ETHNOPHARMACOLOGICAL RELEVANCE: According to the Traditional Chinese Medicine (TCM) tenet that "internal imbalances manifest externally," skin aging reflects deficiencies in qi, blood, and organ systems-particularly the liver and kidneys. Tonifying Traditional Chinese Medicines (TTCM) address these root causes, nourishing the skin and delaying aging through internal regulation, as documented in cl...

Deep learning outperformed radiomics based on MRI in the differentiation of sinonasal small round cell and non-small round cell malignant tumors.

OBJECTIVE: Differentiating sinonasal small round cell malignant tumors (SRCMTs) from non-SRCMTs is challenging due to overlapping MRI features. This s...

Microbiome-Based Modeling of CAR-T Therapy Response in Lymphoma: Insights From Shotgun Metagenomics Sequencing.

The interplay between the commensal microbiota and the mammalian immune system may influence the outcomes of T cell-driven cancer immunotherapies. How...

[Transformation of gastrointestinal surgery diagnosis and treatment models].

In recent years, with the rapid development of medical device and biopharmaceutical technologies, the treatment model of gastric cancer surgery has be...

[Gastric function-preserving surgery (precision surgical treatment): breakthroughs in inheritance, advance in innovation].

Amid the developmental wave of "making breakthroughs while inheriting and forging ahead through innovation" in the field of gastrointestinal surgical ...

[Centennial evolution and innovative practices of functional protection in colorectal cancer surgery].

In the over-century-long history of colorectal tumor surgery, achieving organ function preservation has consistently been a central topic. Currently, ...

[Sphincter-preserving surgery for rectal cancer--From limits to perfection].

Sphincter-preserving therapy for low rectal cancer has always been a difficult and hot topic in colorectal cancer. Advanced understanding of the biolo...

[Trends in the development of clinical diagnosis and treatment models for gastrointestinal tumor surgery in the artificial intelligence era].

Gastrointestinal tumors represent a significant global public health challenge, characterized by high incidence and mortality, which reflect the urgen...

[Precision surgical treatment for middle and low rectal cancer in the era of artificial intelligence].

Precise preoperative assessment and the development of individualized surgical strategies are critical determinants in minimizing operative risks and ...

[Artificial intelligence prediction of surgical difficulty in mid-low rectal cancer: a single-center cohort study].

Objective: This study processes and analyzes rectal MRI images of patients with mid-to-low rectal cancer using deep learning technology, and integrate...

[Current applications and development trends of artificial intelligence in gastric cancer surgery].

With the development of artificial intelligence (AI) technology, AI has demonstrated potential in the diagnosis, treatment, and management of gastric ...

[Clinical Implementation of Artificial Intelligence in Endoscopy: A Human-Artificial Intelligence Interaction Perspective].

Artificial intelligence (AI) for gastrointestinal endoscopy has shown remarkable performance in detecting and characterizing lesions. A randomized con...

Nanoengineering-Based Strategies for Enhancing Dynamic Therapy.

Dynamic therapy has gained increasing attention in the biomedical field due to its high therapeutic efficiency, low cytotoxicity and broad applicabili...

Polyphenols as Modulators of Macrophage Polarization: Mechanisms and Therapeutic Potential in Chronic Inflammatory Diseases.

Macrophage polarization between pro-inflammatory M1 and anti-inflammatory M2 phenotypes is pivotal in chronic inflammatory diseases, offering a key th...

Machine learning-driven dynamic prognosis for primary colorectal lymphoma.

Computational identification of potential MMP-2 inhibitors in cancer using machine learning, molecular docking, and dynamics simulations.

Matrix metalloproteinase-2 (MMP-2) is a zinc-dependent endopeptidase which plays a key role in the extracellular matrix-remodeling and cancer metastas...

HCAR1 antagonist screening based on boundary-selected negative sampling strategy and multi-level graph neural network.

BACKGROUND AND OBJECTIVE: Hydroxycarboxylic acid receptor 1 (HCAR1), also known as the lactate receptor, is closely associated with tumorigenesis and ...

MRI-based multilevel radiomics and transformer features for predicting radiation-induced carotid artery injury after nasopharyngeal carcinoma radiotherapy: A multicenter study.

PURPOSE: To develop and validate an MRI-based fusion model (Rad-SRad-SwinT) integrating conventional radiomics (Rad), subregional radiomics (SRad), an...

Anti-angiogenesis effect of Baiying Juhua Decoction on the non-small cell lung cancer: integrating pharmacology, multi-machine learning and experimental investigation.

Baiying Juhua Decoction (BYJHD) is a well-established traditional Chinese herbal formula primarily composed of Solanum lyratum and chrysanthemum, whic...