Oncology/Hematology

Latest AI and machine learning research in oncology/hematology for healthcare professionals.

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Pan-cancer analysis identifies immunoproteasome as the predominant survival-associated component of antigen processing machinery.

Neoantigens are critical targets for cancer immunotherapy, yet the relationship between experimentally validated neoantigen burden and antigen processing machinery (APM) expression in determining clinical outcomes remains unclear. We mapped CEDAR-annotated neoantigens (CENs) onto mutation data from 43,980 patients across 14 cancer types using cBioPortal. APM gene expression was correlated with sur...

Jun 27 2026 42364494

Plasma metabolomics combined with machine learning for postoperative prognostic stratification in hormone receptor-positive/human epidermal growth factor receptor 2-negative early breast cancer.

BACKGROUND AND AIMS: Hormone receptor-positive/human epidermal growth factor receptor 2-negative (HR+/HER2-) breast cancer (BC) accounts for the majority of BC cases. Although early-stage patients generally have favorable outcomes, recurrence and metastasis substantially worsen prognosis. We aimed to evaluate whether plasma metabolomics combined with machine learning could predict postoperative ou...

Jun 27 2026 42364806
TACE-induced liver injury in hepatocellular carcinoma: mechanisms, prediction, and prevention in the era of gut microbiota and inflammasome research.

Transarterial chemoembolization (TACE) is a cornerstone locoregional therapy for hepatocellular carcinoma (HCC), yet most candidates also have cirrhos...

Jun 27 2026 42364906
Phase-only synthesis of cosecant-squared patterns with reduced sidelobes in large planar arrays via physics-informed deep neural networks.

This paper introduces a deep learning-based framework for phase-only synthesis of cosecant-squared (csc²) radiation patterns in planar antenna arrays ...

Jun 27 2026 42365069
MRI-based quantification of intratumoral heterogeneity for predicting recurrence risk in ER+/HER2- breast cancer.

OBJECTIVES: The need for a cost-effective, rapid, and increasingly accessible alternative to the 21-gene assay prompted this study, which developed a ...

Jun 27 2026 42365208
CBINN: Cancer Biology-Informed Neural Network for Unknown Parameter Estimation and Missing Physics Identification.

The dynamics of tumor-immune interactions within a complex tumor microenvironment are typically modeled using a system of ordinary differential equati...

Jun 27 2026 42365212
Multi-cohort integration and machine learning identify CPVL as a novel oncogenic driver in gastric cancer.

BACKGROUND: Gastric cancer (GC) remains a leading cause of cancer-related mortality worldwide, and the prognosis of advanced GC remains poor. Systemat...

Jun 27 2026 42365218
Potential evaluation of SULT1A3 as an early diagnostic marker for nasopharyngeal carcinoma: a study based on serum proteomics screening and ELISA validation.

BACKGROUND: Nasopharyngeal carcinoma (NPC) represents a highly prevalent and aggressive malignancy endemic to Southeast Asia. Early and accurate diagn...

Jun 27 2026 42365246
Biomarker-based machine learning for malignant transformation in oral potentially malignant disorders: a scoping review.

Oral squamous cell carcinoma (OSCC) is often preceded by oral potentially malignant disorders (OPMDs). Despite this known association, the transition ...

Jun 27 2026 42365263
O-RADS for assessment of adnexal lesions: current status, challenges and future directions.

The Ovarian-Adnexal Reporting and Data System (O-RADS), developed by the American College of Radiology (ACR), provides a standardized, evidence-based ...

Jun 27 2026 42365347
Navigating AI and machine learning in cancer research: an end-to-end translational framework.

Cancer is a complex and heterogeneous disease that is characterized by multi-level biological variability. Advances in high-throughput technologies ha...

Jun 27 2026 42365374
The Addition of Computer-Aided Detection (CADe) to Texture and Color Enhancement Imaging (TXI) Does Not Improve Adenoma Detection Rate During Colonoscopy: A Prospective Study.

OBJECTIVES: Early detection and resection of colorectal polyps prevent their progression toward advanced adenocarcinomas. The use of Texture and Color...

Jun 26 2026 42363424
Advancing breast cancer diagnosis through ultrasound imaging: A cross-attention multi-scale vision transformer approach with comparative analysis against ResNet architectures.

In recent years, the field of medical imaging has witnessed substantial progress due to the integration of advanced machine learning techniques, parti...

Jun 26 2026 42363450
Integrative analysis of machine learning and single-cell sequencing identifies IGHG1 as a therapeutic target for epimedium in diabetes-gastric cancer comorbidity.

BACKGROUND: The clinical comorbidity of diabetes mellitus (DM) and gastric cancer (GC) presents a significant healthcare challenge, as these two condi...

Jun 26 2026 42364318
Radiation scatter at fluoroscopy-guided endoscopic procedures: Building towards further optimization.

INTRODUCTION: Exposure to ionizing radiation by endoscopy personnel during fluoroscopy-guided procedures remains a health hazard. We aimed to evaluate...

Jun 26 2026 42358121
Machine learning prediction of axillary lymph node metastasis using multimodal ultrasound in breast cancer.

OBJECTIVES: Accurate prediction of axillary lymph node metastasis (ALNM) is crucial for tailoring breast cancer treatments, this study aimed to develo...

Jun 26 2026 42359462
Artificial intelligence in genitourinary oncology: publication trends and systematic review.

OBJECTIVE: To conduct an analysis of publication trends and a systematic review of randomized controlled trials (RCTs) to characterize the current sta...

Jun 26 2026 42360093
Pathology-informed Generative Adversarial Network Augmentation Improves Classification of Peripheral Nerve Sheath Tumors by Modeling Morphological Variability: A Pilot Investigation.

BACKGROUND: Peripheral nerve sheath tumors (PNSTs) of the head and neck (H&N) show histopathological overlap. Although convolutional neural networks (...

Jun 26 2026 42360366
AI-assisted digital breast tomosynthesis as a decision-support tool for post-neoadjuvant surgical planning in breast cancer.

PURPOSE: Accurate assessment of residual disease after neoadjuvant chemotherapy (NAC) is essential for surgical planning and prevention of incomplete ...

Jun 26 2026 42360378
Multidrug resistance in cancer: current understandings and future perspective.

Multidrug resistance (MDR) remains the core clinical barrier limiting the achievement of durable and effective treatment for various tumors. With the ...

Jun 26 2026 42360409
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