Oncology/Hematology

Latest AI and machine learning research in oncology/hematology for healthcare professionals.

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Resisting the (re-)medicalisation of dying and grief in the post-digital age: Natural language processing and qualitative analysis of data from internet support forums.

In the mid-twentieth century, the social movement of death revivalism sought to resist the medicalisation of dying and grief through promotion of the dying person retaining autonomy, and societal openness toward death and bereavement. Despite this advocacy, present-day dying in high income countries is largely institutionalised, with value placed on control over the body and emotions. These phenom...

Dec 24 2023 38593612

Body composition radiomic features as a predictor of survival in patients with non-small cellular lung carcinoma: A multicenter retrospective study.

OBJECTIVES: This study combined two novel approaches in oncology patient outcome predictions-body composition and radiomic features analysis. The aim of this study was to validate whether automatically extracted muscle and adipose tissue radiomic features could be used as a predictor of survival in patients with non-small cell lung cancer.

Dec 24 2023 38237479
ExoMechHand prototype development and testing with EMG signals for hand rehabilitation.

Rehabilitation is a major requirement to improve the quality of life and mobility of patients with disabilities. The use of rehabilitative devices wit...

Dec 23 2023 38418024
Deep learning-based design and screening of benzimidazole-pyrazine derivatives as adenosine A receptor antagonists.

The Adenosine A receptor (AAR) is considered a novel potential target for the immunotherapy of cancer, and AAR antagonists have an inhibitory effect o...

Dec 22 2023 38133953
APOLLO 11 Project, Consortium in Advanced Lung Cancer Patients Treated With Innovative Therapies: Integration of Real-World Data and Translational Research.

INTRODUCTION: Despite several therapeutic efforts, lung cancer remains a highly lethal disease. Novel therapeutic approaches encompass immune-checkpoi...

Dec 22 2023 38262770
Cuproptosis gene-related, neural network-based prognosis prediction and drug-target prediction for KIRC.

BACKGROUND: Kidney renal clear cell carcinoma (KIRC), as a common case in renal cell carcinoma (RCC), has the risk of postoperative recurrence, thus i...

Dec 22 2023 38131663
Automated identification and quantification of metastatic brain tumors and perilesional edema based on a deep learning neural network.

PURPOSE: This paper presents a deep learning model for use in the automated segmentation of metastatic brain tumors and associated perilesional edema.

Dec 22 2023 38133789
Optical imaging for screening and early cancer diagnosis in low-resource settings.

Low-cost optical imaging technologies have the potential to reduce inequalities in healthcare by improving the detection of pre-cancer or early cancer...

Dec 22 2023 39301200
A nomogram based on ultrasound radiomics for predicting the invasiveness of cN0 single papillary thyroid microcarcinoma.

BACKGROUND: Up to 15.3% of papillary thyroid microcarcinoma (PTMC) patients with negative clinical lymph node metastasis (cN0) were confirmed to have ...

Dec 22 2023 38229850
Application of deep learning in the diagnosis and evaluation of ulcerative colitis disease severity.

BACKGROUND: Achieving endoscopic and histological remission is a critical treatment objective in ulcerative colitis (UC). Nevertheless, interobserver ...

Dec 22 2023 38144424
Identification of oral therapeutics using an AI platform against the virus responsible for COVID-19, SARS-CoV-2.

This study introduces a sophisticated computational pipeline, , designed for the discovery of antiviral drugs based on their interactions within the ...

Dec 22 2023 38186640
Transfer learning improves pMHC kinetic stability and immunogenicity predictions.

The cellular immune response comprises several processes, with the most notable ones being the binding of the peptide to the Major Histocompability Co...

Dec 21 2023 38577265
Deep learning for [F]fluorodeoxyglucose-PET-CT classification in patients with lymphoma: a dual-centre retrospective analysis.

BACKGROUND: The rising global cancer burden has led to an increasing demand for imaging tests such as [F]fluorodeoxyglucose ([F]FDG)-PET-CT. To aid im...

Dec 21 2023 38135556
Exploring the advances of single-cell RNA sequencing in thyroid cancer: a narrative review.

Thyroid cancer, a prevalent form of endocrine malignancy, has witnessed a substantial increase in occurrence in recent decades. To gain a comprehensiv...

Dec 21 2023 38129369
Near-Infrared Spectroscopy with Supervised Machine Learning as a Screening Tool for Neutropenia.

The use of non-invasive tools in conjunction with artificial intelligence (AI) to detect diseases has the potential to revolutionize healthcare. Near-...

Dec 21 2023 38276224
Innovative strategies to predict and prevent the risk for malnutrition in child, adolescent, and young adult cancer survivors.

Children, adolescents, and young adult cancer survivors (CAYAs) constitute a growing population requiring a customized approach to mitigate the incide...

Dec 21 2023 38188871
Deep learning for malignancy risk estimation of incidental sub-centimeter pulmonary nodules on CT images.

OBJECTIVES: To establish deep learning models for malignancy risk estimation of sub-centimeter pulmonary nodules incidentally detected by chest CT and...

Dec 20 2023 38114849
Microsatellite Instability, Mismatch Repair, and Tumor Mutation Burden in Lung Cancer.

Since US Food and Drug Administration approval of programmed death ligand 1 (PD-L1) as the first companion diagnostic for immune checkpoint inhibitors...

Dec 20 2023 38692812
Therapeutic potential of mangiferin in cancer: Unveiling regulatory pathways, mechanisms of action, and bioavailability enhancements - An updated review.

Mangiferin (MGF) is a phenolic compound, which is a major source of MGF is the mango tree. MGF possesses some antioxidant, anti-inflammatory, and cyto...

Dec 20 2023 38455223
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