Oncology/Hematology

Latest AI and machine learning research in oncology/hematology for healthcare professionals.

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Interpretable multitask model for clinical pathology image prediction and interpretation.

Deep learning (DL)-based pathological image modelling and analysis approaches offer transformative potential for early cancer diagnostics, yet limited sample sizes and a lack of interpretability often hinder efficient clinical translation. Here, we present the interpretable Multi-Task Digital Pathology Model (iMDPath), an end-to-end, highly explainable multi-task deep learning framework that simul...

May 19 2026 42156411

Temporally consistent longitudinal brain tumor segmentation using a temporal spatial transformer network.

Proper monitoring of tumor progression and evaluation of treatment responses highly depend on longitudinal brain tumor segmentation from MRI data. Current deep learning methodologies have mainly concentrated on analyzing single-time-point images, which restricts the ability to incorporate temporal dynamics during the segmentation process. The study proposes a new approach called Temporal-Spatial T...

May 19 2026 42156537
Robust transcriptomic signatures of Alzheimer's disease progression: validated explainable AI approach.

The lack of validated stage-specific biomarkers hampers the understanding of Alzheimer's disease (AD) progression and clinical translation. Current tr...

May 19 2026 42156857
MANet: a multimodal attention convolutional neural network for brain tumor classification.

Classification of brain tumors is a difficult problem in medical imaging analysis. Over the past few years, various deep learning-based techniques hav...

May 19 2026 42156952
Development and validation of artificial intelligence-based model for bladder cancer immunophenotyping using whole slide images.

The classification of immunophenotypes in muscle-invasive bladder cancer (MIBC) is critical for predicting immunotherapy response and clinical outcome...

May 19 2026 42156975
Deep learning-based prediction of lymph node metastasis and occult tumor cells in gastric cancer using histopathological images: a retrospective study.

BACKGROUND: Lymph node metastasis (LNM) is an important prognostic factor but is often underdiagnosed due to limitations in conventional assessment me...

May 19 2026 42156979
A deep learning system for non-invasive breast cancer diagnosis with multimodal data.

Early and accurate diagnosis of breast cancer is critical for minimizing needle biopsies and enhancing patient outcomes and requires effective integra...

May 19 2026 42157015
An interpretable machine learning model integrating [18F]FDG PET/CT radiomics and clinical features for predicting perforation following chemotherapy in gastrointestinal lymphoma: a multicenter study.

BACKGROUND: Perforation following chemotherapy in gastrointestinal lymphoma (PFCGL) is a rare but severe and life-threatening complication. Early pre-...

May 19 2026 42151619
Artificial Intelligence for Molecular Subtyping in Unresectable Gallbladder Cancer: A Proof-of-Concept Study for CT-based HER2 Status Prediction.

BACKGROUND/AIMS: Human epidermal growth factor receptor 2 (HER2) overexpression is a critical therapeutic target in gallbladder cancer (GBC), but dete...

May 19 2026 42306236
Artificial intelligence integrated multi-omics and multimodal studies promote the efficacy of neoadjuvant chemotherapy in breast cancer: opportunities, challenges, and future perspectives.

BACKGROUND: Neoadjuvant chemotherapy (NAC) is a critical therapeutic strategy for locally advanced breast cancer; however, its clinical utility is con...

May 18 2026 42152095
From data to decision: a clinical pipeline for wearable AI in early cardiotoxicity detection.

Chemotherapy-induced cardiotoxicity (CIC) is a leading cause of morbidity in cancer survivors, as conventional surveillance often detects cardiac dysf...

May 18 2026 42152136
Diagnostic performance of artificial intelligence models in hepatocellular carcinoma: a systematic review and diagnostic meta-analysis.

OBJECTIVE: To systematically evaluate the diagnostic performance of artificial intelligence (AI) models for hepatocellular carcinoma (HCC) and to pool...

May 18 2026 42144587
Synthetic Inducible Bacteria Normalize the Microenvironment of Refractory Tumors, Potentiating Checkpoint Inhibitor Responses.

Immunotherapy has transformed cancer treatment but remains ineffective in many solid tumors, largely due to the immunosuppressive tumor microenvironme...

May 18 2026 42145056
P4NSU: Projection-Based Pretraining for Nonlinear Sparse Unmixing in Spectral Imaging.

Accurate quantification of components with spectral imaging (e.g., hyperspectral and Raman) is fundamentally challenged by nonlinear mixing effects. T...

May 18 2026 42145112
Radiation biomarker screening and dose reconstruction based on machine learning.

PURPOSE: Nuclear emergency medical rescue is a critical component of the nuclear emergency response system, playing a vital role in safeguarding publi...

May 18 2026 42148888
Clinical outcomes and predictors of response to PD-(L)1 blockade in patients with NSCLC without actionable genomic alterations who never used tobacco.

PURPOSE: Predictive biomarkers of response to immune checkpoint inhibitors (ICI) remain poorly defined in patients with non-small cell lung cancer (NS...

May 18 2026 42149140
Beyond gross total resection (GTR): Deep peritumoral radiomics for predicting overall survival (OS) and O6-methylguanine-DNA-methyltransferase promoter methylation (MGMTpm) status in glioblastoma multiforme.

BACKGROUND & OBJECTIVE: Glioblastoma Multiforme (GBM) is an aggressive and highly heterogeneous brain tumor with poor survival outcomes. While convent...

May 18 2026 42149212
Peptides as integrative modulators for clinical prognosis and targeted therapy in pancreatic cancer.

Pancreatic cancer remains a formidable global health challenge, ranking as the twelfth most common malignancy yet claiming an outsized toll with disma...

May 18 2026 42149255
Artificial intelligence for risk-stratified breast cancer screening: a systematic review of evidence, clinical integration, and ethical implications in risk assessment tools.

BACKGROUND: Conventional age-based breast cancer screening ignores substantial inter-individual risk variation, contributing to overdiagnosis, false p...

May 18 2026 42149286
Calcite nanoparticles as advanced, pH-responsive platforms for cancer therapy: a comprehensive and critical review.

Nanomedicine offers powerful opportunities to overcome the pharmacokinetic and microenvironmental limitations of conventional chemotherapy, particular...

May 18 2026 42150571
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