Oncology/Hematology

Latest AI and machine learning research in oncology/hematology for healthcare professionals.

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Showing 14661-14680 of 19,058 articles

Leveraging Longitudinal Patient-Reported Outcomes Trajectories to Predict Survival in Non-Small-Cell Lung Cancer

Despite their potential, patient-reported outcomes (PROs) are often underutilized in clinical decision-making, especially when improvements in PROs do not align with clinical outcomes. This misalignment may result from insufficient analytical methods that overlook the temporal dynamics and substantial variability of PROs data. To address these gaps, we developed a novel approach to investigate the...

End-to-end prediction of clinical outcomes in head and neck squamous cell carcinoma with foundation model-based multiple instance learning

Foundation models (FMs) show promise in medical AI by learning flexible features from large datasets, potentially surpassing handcrafted radiomics. Outcome prediction of head and neck squamous cell carcinomas (HNSCC) with FMs using routine imaging remains unexplored. To evaluate end-to-end FM-based multiple instance learning (MIL) for 2-year overall survival (OS), locoregional control (LRC), and f...

Image-based Explainable Artificial Intelligence Accurately Identifies Myelodysplastic Neoplasms Beyond Conventional Signs of Dysplasia

Evaluation of bone marrow morphology by experienced hematologists is key in the diagnosis of myeloid neoplasms, especially to detect subtle signs of d...

Few-Shot Learning for Prostate Cancer Detection on MRI: Comparative Analysis with Radiologists’ Performance

Deep-learning models for prostate cancer detection often require large datasets, which can be challenging to obtain and may lead to domain shift issue...

Automated Segmentation of Trunk Musculature with a Deep CNN Trained from Sparse Annotations in Radiation Therapy Patients with Metastatic Spine Disease

Given the high prevalence of vertebral fractures post-radiotherapy in patients with metastatic spine disease, accurate and rapid muscle segmentation c...

Fusing Data from CT Deep Learning, CT Radiomics and Peripheral Blood Immune profiles to Diagnose Lung Cancer in Symptomatic Patients

Lung cancer is the leading cause of cancer-related deaths. Diagnosis at late stages is common due to the largely non-specific nature of presenting sym...

A Lung CT Foundation Model Facilitating Disease Diagnosis and Medical Imaging

The concomitant development and evolution of lung computed tomography (CT) and artificial intelligence (AI) has allowed non-invasive lung imaging to b...

An autoantibody-based machine learning classifier for the detection of early-stage non-small cell lung cancer

The humoral immune system plays a significant role in the immune response to cancer but is challenging to study at scale. We used programmable phage i...

Multi-resolution vision transformer model for skin cancer subtype classification using histopathology slides

Digital pathology has significantly advanced cancer diagnosis by enabling high-resolution visualisation and assessment of tissue specimens. However, t...

Artificial Intelligence in Pancreatic Intraductal Papillary Mucinous Neoplasm Imaging: A Systematic Review

Based on the Fukuoka and Kyoto international consensus guidelines, the current clinical management of intraductal papillary mucinous neoplasm (IPMN) l...

Prospective Blinded evaluation of Thermalytix, an artificial intelligence-enhanced breast thermal imaging software, correlated with radiologist-interpreted mammograms: Results of an exploratory study in Zambia

While mammography is commonly used for breast cancer detection, its widespread implementation in resource-constrained nations is challenging. Artifici...

Diagnosis of Blood Diseases and Disorders with Topological Deep Learning

Blood diseases and disorders, including leukemia and infectious diseases of red blood cells, pose significant diagnostic challenges due to their compl...

Personalized circulating tumor DNA dynamics predict survival and response to immune checkpoint blockade in recurrent/metastatic head and neck cancer

Recurrent/metastatic head and neck squamous cell carcinoma (R/M HNSCC) is an aggressive cancer with a median overall survival of only 12 months. Exist...

AI-Powered Exploration of IGF2BP3 as a Prognostic Biomarker in Chronic Myeloid Leukemia Progression and Disease Stratification

Chronic Myeloid Leukemia (CML) progresses through chronic, accelerated, and blast crisis phases, making disease stratification and therapeutic respons...

Integration of CA attention and KAN algorithm to predict EGFR mutation status in lung cancer

Epidermal Growth Factor Receptor (EGFR) mutations are critical biomarkers for targeted therapies in non-small cell lung cancer (NSCLC). However, conve...

Alterations in the hepatic microenvironment following direct-acting antiviral therapy for chronic hepatitis C

Background and aims. The first direct-acting antivirals (DAAs) to treat the viral hepatitis C (HCV) became available in 2011. Despite numerous clinica...

Prognostic predictions in psychosis: exploring the complementary role of machine learning models

Predicting outcomes in schizophrenia spectrum disorders is challenging due to the variability of individual trajectories. While machine learning (ML) ...

Impact of a machine learning-powered algorithm on pathologist HER2 IHC scoring in breast cancer

HER2 expression level is a key factor in determining the optimal treatment course for breast cancer patients. Roughly 15% of breast cancers are HER2(+...

Multimodal AI-Based Risk Stratification for Distant Metastasis in Nasopharyngeal Carcinoma

The TNM staging system is the primary tool for treatment decisions in nasopharyngeal carcinoma (NPC). However, therapeutic outcomes vary considerably ...

A Scalable Method for Validated Data Extraction from Electronic Health Records with Large Language Models

Extracting and structuring relevant clinical information from electronic health records (EHRs) remains a challenge due to the heterogeneity of systems...

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