Oncology/Hematology

Latest AI and machine learning research in oncology/hematology for healthcare professionals.

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Showing 14801-14820 of 19,058 articles

Explainable AI for Precision Oncology: A Task-Specific Approach Using Imaging, Multi-omics, and Clinical Data

Despite continued advances in oncology, cancer remains a leading cause of global mortality, highlighting the need for diagnostic and prognostic tools that are both accurate and interpretable. Unimodal approaches often fail to capture the biological and clinical complexity of tumors. In this study, we present a suite of task-specific AI models that leverage CT imaging, multi-omics profiles, and str...

Artificial Intelligence Agent: AI-HOPE-TP53 Enables Pathway-Centric Analysis of TP53-Driven Molecular Alterations in Colorectal Cancer Precision Oncology

Early-onset colorectal cancer (EOCRC) is rising rapidly, especially among populations at risk who experience disproportionate incidence and mortality. The TP53 pathway, frequently altered in CRC, regulates key processes such as DNA repair and apoptosis. Despite its clinical relevance, TP53 dysregulation remains understudied in EOCRC, particularly in populations at risk. Current tools lack support ...

A multi-modal deep learning framework for predicting PSA progression-free survival in metastatic prostate cancer using PSMA PET/CT imaging

PSMA PET/CT imaging has been increasingly utilized in the management of patients with metastatic prostate cancer (mPCa). Imaging biomarkers derived fr...

Cross-Modal Deep Learning for Integrated Molecular Diagnosis of Cancer: A Prospective Multicenter Study

Accurate integration of histological and molecular features is central to modern cancer diagnostics, but it is often hampered by extended turnaround t...

White matter characterization in regions of edema surrounding meningioma brain tumor using diffusion MRI

White matter (WM) tract detection is critical in presurgical planning of tumor resection however, standard-of-care imaging techniques including T1-wei...

Benign-Malignant Classification of Pulmonary Nodules in CT Images Based on Fractal Spectrum Analysis

This study reveals that pulmonary nodules exhibit distinct multifractal characteristics, with malignant nodules demonstrating significantly higher fra...

Revolutionizing Lung Cancer Detection: Evaluating AI Models for VOC Analysis and Unveiling Key Exhaled Biomarkers

Volatile Organic Compounds (VOCs) are organic chemicals that readily vaporize at room temperature and are emitted from diverse sources, including pain...

SuReCAN: a suite of user-friendly Galaxy machine learning workflows to predict survival and treatment response of cancer patients

Cancer is one of the leading lethal causes worldwide, with enormous impact on healthcare, economy and society. One of the main challenges of clinical ...

Artificial Intelligence (AI)-Powered H&E Whole-Slide Image Analysis of Tertiary Lymphoid Structure (TLS) Independently Predicts Survival in Patients with Non-Small Cell Lung Cancer (NSCLC) Receiving Immunotherapy

Tertiary lymphoid structures (TLSs) within the tumor microenvironment have emerged as potential indicators of treatment response to immune checkpoint ...

Scoring Physician Risk Communication in Prostate Cancer Using Large Language Models

Effective risk communication is essential to shared decision-making in prostate cancer care. However, the quality of physician communication of key tr...

Resting-State Functional Connectivity of the Fronto-Limbic and Default Mode Networks as Predictors of Antidepressant Response in Major Depressive Disorder

Major depressive disorder (MDD) is a leading cause of disability worldwide, yet treatment response to antidepressants remains highly variable, with a ...

Stacked CNN Architectures for Robust Brain Tumor MRI Classification

Brain tumor classification using MRI scans is crucial for early diagnosis and treatment planning. In this study, we first train a single Convolutional...

Human breast cancer is linked to Epstein-Barr virus because it targets stem cells: bioinformatic chromosome correlations

Breast cancer originates from rare “cancer stem cells”. Stem cells are especially susceptible to becoming cancerous because they readily become differ...

Longitudinal Cardiorespiratory Wearable Sleep Staging in the Home

There is a growing interest in performing automated, longitudinal tracking of sleep in the home environment using wearables and machine learning. Wear...

HONeYBEE: Enabling Scalable Multimodal AI in Oncology Through Foundation Model–Driven Embeddings

HONeYBEE (Harmonized ONcologY Biomedical Embedding Encoder) is an open-source framework that integrates multimodal biomedical data for oncology applic...

A Systematic Review of Multimodal Deep Learning and Machine Learning Fusion Techniques for Prostate Cancer Classification

Prostate cancer remains one of the most prevalent malignancies and a leading cause of cancer-related deaths among men worldwide. Despite advances in t...

Ensemble uncertainty estimation improves skin cancer malignancy prediction

Widespread access to imaging technologies and stronger machine learning (ML) architectures for dermatology tasks such as malignancy prediction have sp...

Artificial Intelligence quantified prostate specific membrane antigen imaging in metastatic castrate-resistant prostate cancer patients treated with Lutetium-177-PSMA-617

The VISION study1 found that Lutetium-177 (177Lu)–PSMA-617 (“Lu-177”) improved overall survival in metastatic castrate resistant prostate cancer (mCRP...

A hybrid computer vision model to predict lung cancer in diverse populations

Disparities of lung cancer incidence exist in Black populations and screening criteria underserve Black populations due to disparately elevated risk i...

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