Oncology/Hematology

Latest AI and machine learning research in oncology/hematology for healthcare professionals.

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Showing 14821-14840 of 19,058 articles

Ensemble Deep Learning for Histopathological Breast Cancer Detection

Breast cancer remains one of the leading causes of mortality among women worldwide, and early and accurate diagnosis is essential for effective treatment. In this study, we propose an ensemble deep learning approach for classifying histopathological images of breast cancer using the BreaKHis dataset. Two state-of-the-art convolutional neural network architectures, ResNet50 and DenseNet121, were fi...

Acute myeloid leukemia risk stratification in younger and older patients through transcriptomic machine learning models

Acute Myeloid Leukemia (AML) is a genetically and clinically heterogeneous disease that can develop at any age. While AML incidence increases with age and distinct genetic alterations are observed in younger versus older patients, current classification systems do not incorporate age as a defining factor. In this study, we analyzed RNA-seq data from 404 AML patients at initial diagnosis, leveragin...

Automated Assessment of Choroidal Mass Dimensions Using Static and Dynamic Ultrasonographic Imaging

To develop and validate an artificial intelligence (AI)-based model that automatically measures choroidal mass dimensions on Bâ–¡scan ophthalmic ultraso...

Development of a dynamic counterfactual risk stratification strategy for newly diagnosed acute myeloid leukemia patients treated with venetoclax and azacitidine

The objective of this study was to develop a flexible risk stratification strategy for Acute Myeloid Leukemia (AML) that is specific for venetoclax pl...

Artificial Intelligence-Guided Molecular Determinants of PI3K Pathway Alterations in Early-Onset Colorectal Cancer Among High-Risk Groups Receiving FOLFOX

Early-onset colorectal cancer (EOCRC), defined as diagnosis before age 50, is rising rapidly and disproportionately affects high-risk populations, par...

Large Language Models Improve Cancer Survival Prediction Using Real-World Clinical Notes

In medical documentation, vast amounts of unstructured text are generated that are still underutilized in current prognostic models. We investigate th...

Analysis of Genome-Wide Cell-Free DNA Fragment Length Distributions in Colorectal Cancer

Each piece of cell-free DNA (cfDNA) has a length determined by the exact metabolic conditions in the cell it belonged to at the time of cell death. Th...

Quantitative Analysis of Breast Nuclei Morphology for Cancer Diagnosis Using Supervised Machine Learning

Breast cancer is the most frequently diagnosed malignancy among women worldwide and a major cause of mortality. Early and accurate detection is vital ...

Responsible AI in Action: Planning through Implementation of a Mortality Model for Palliative Care

Interest in the use of prediction models to support referrals to palliative care is surging. Few high-performing models have been developed, implement...

Deep Learning-Assisted Skeletal Muscle Radiation Attenuation at C3 Predicts Survival in Head and Neck Cancer

Head and neck cancer (HNC) patients face an increased risk of malnutrition due to lifestyle, tumor localization, and treatment effects. While skeletal...

A quantitative comparison between human experts and AI at estimating tumor-stroma ratio

The tumor–stroma ratio (TSR) is an established prognostic biomarker across several cancer types, yet its manual assessment remains labour-intensive an...

Diagnostic Codes in AI prediction models and Label Leakage of Same-admission Clinical Outcomes

Artificial intelligence (AI) and statistical models designed to predict same-admission outcomes for hospitalized patients, such inpatient mortality, o...

SROTAS IQ: An AI-Based Clinical Trial Matching Platform: A Validation Study in Breast Cancer

To evaluate the performance of SROTAS IQ, a custom fine-tuned large language model (LLM), in automating clinical trial eligibility screening for breas...

Closing the Lung Cancer Screening Gap in FQHCs with AI-Powered Clinical Decision Support

Lung cancer remains the leading cause of cancer-related mortality in the United States, with screening adherence rates below 16% nationally and even l...

Integrative Approaches for Skin Cancer Detection and Classification : A Dual modal Analysis

The early detection of skin cancer is of critical importance, as it can lead to in fatal outcomes if left unaddressed. Given the limited accessibility...

A Case Study on Colposcopy-Based Cervical Cancer Staging Reveals an Alarming Lack of Data Sharing Hindering the Adoption of Machine Learning in Clinical Practice

The inbuilt ability to adapt existing models to new applications has been one of the key drivers of the success of deep learning models. Thereby, shar...

Integration of Gene Expression and Digital Histology to Predict Treatment-Specific Responses in Breast Cancer

Deep learning models applied to digital histology can predict gene expression signatures (GES) and offer a low-cost, rapidly available alternative to ...

Urinary pesticide profiles and liver disease risk in Thailand: a machine-learning risk-prediction model

Building on evidence linking urinary glyphosate to chronic liver disease (CLD) and hepatocellular carcinoma (HCC), we developed urinary pesticide prof...

Optical Microscopy Predictions of Focal Recurrence in Glioblastoma

A hallmark of glioblastoma (GBM) is disease recurrence, which occurs in all patients despite tumor resection, radiation, and chemotherapy. A critical ...

MyGESig: a population-specific gene signature improves survival prediction in Malaysian breast cancer patients

Accurate prognostic models are essential for guiding treatment decisions and improving patient outcomes in breast cancer. To achieve this, population-...

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