Oncology/Hematology

Latest AI and machine learning research in oncology/hematology for healthcare professionals.

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Showing 14841-14860 of 19,058 articles

Causal Machine Learning Analysis of All-Cause Mortality in Japanese Atomic-Bomb Survivors

The health consequences of ionizing radiation have long been studied, yet significant uncertainties remain, particularly at low doses. In particular, traditional dose-response models such as linear, linear-quadratic, threshold, or hormesis models, all impose specific assumptions about low-dose effects. In addition, while the goal of radiation epidemiological studies is ideally to uncover causal re...

A Plasma-based Deep Proteomic Platform for Early-Stage Breast Cancer Detection

Despite the widespread use of mammography as the standard of care for breast cancer screening, its accuracy remains limited for select patient populations, such as women with high breast density. Liquid biopsy-based tests offer an accessible complement to conventional screening methods. Here, we conducted a case-control study to develop a plasma-based protein classifier to distinguish between earl...

Atherosclerosis biomarkers via mitochondrial permeability transition necrosis gene analysis

Atherosclerosis (AS) is a major cause for cardiovascular disease, and mitochondrial permeability transition driven necrosis (MPTDN) is often associate...

Feature-Based Machine Learning for Brain Metastasis Detection Using Clinical MRI

Brain metastases represent one of the most common intracranial malignancies, yet early and accurate detection remains challenging, particularly in cli...

AI-based synthetic simulation CT generation from diagnostic CT for simulation-free workflow of spinal palliative radiotherapy

Current radiotherapy (RT) planning workflows rely on pre-treatment simulation CT (sCT), which can significantly delay treatment initiation, particular...

Cross-Species and Tissue-Agnostic Prediction of Human Cancer Treatment Response using AI-Powered Cellular Morphometric Biomarkers from a Genetically Diverse Erbb2 Mouse Model

The success of drug development relies heavily on the use of animal models. However, increasing evidence shows that discoveries in these models often ...

Deep Learning for Breast Mass Discrimination: Integration of B-Mode Ultrasound & Nakagami Imaging with Automatic Lesion Segmentation

This study aims to enhance breast cancer diagnosis by developing an automated deep learning framework for real-time, quantitative ultrasound imaging. ...

Revealing Shared Tumor Microenvironment Dynamics Related to Microsatellite Instability Across Different Cancers Using Cellular Social Network Analysis

Microsatellite instability (MSI) is a key biomarker for immunotherapy response and prognosis across multiple cancers, yet its identification from rout...

Clinical Validation of RlapsRisk BC in an international multi-cohorts setting

This study evaluated the prognostic performance of RlapsRisk BC, a multimodal deep learning tool designed to predict distant recurrence-free interval ...

Assessment of a zero-shot large language model in measuring documented goals-of-care discussions

Goals-of-care (GOC) discussions and their documentation are important process measures in palliative care. However, existing natural language processi...

Genomic Classification of Acute Lymphoblastic Leukemia Using AI: Towards Personalized Medicine

Acute lymphoblastic leukemia is a highly heterogeneous hematologic malignancy that poses significant challenges for clinicians in terms of early detec...

HGACL-DRP: Heterogeneous Graph Attention Dual-Perturbation Contrastive Learning Network for Drug Response Prediction

The marked heterogeneity of cancer poses a substantial challenge to precision drug therapy, resulting in considerable variability in patient responses...

Robust Disease Prognosis via Diagnostic Knowledge Preservation: A Sequential Learning Approach

Accurate disease prognosis is essential for patient care but is often hindered by the lack of long-term data. This study explores deep learning traini...

Retrospective Validation of an Artificial Intelligence System for Diagnostic Assessment of Prostate Biopsies on the ProMort Cohort: Study Protocol

Prostate cancer diagnosis and treatment planning depend on accurate histopathological assessment of needle biopsies, particularly through the Gleason ...

Performance assessment of large language models in cancer staging: Comparative analysis of Mistral models

Cancer staging plays a critical role in treatment planning and prognosis but is often embedded in unstructured clinical narratives. To automate the ex...

A Hybrid Deep Learning Ensemble for Accurate Skin Cancer Classification

Skin cancer is one of the most common types of cancer worldwide, and early detection is crucial for improving patient survival rates. In this study, w...

Development of a RAG-based Expert LLM for Clinical Support in Radiation Oncology

The ability of pre-trained large language models (LLMs) to rapidly master novel natural language processing tasks holds transformative potential. Howe...

Leveraging transfer learning from Acute Lymphoblastic Leukemia (ALL) pretraining to enhance Acute Myeloid Leukemia (AML) prediction

We overcome current limitations in Acute Myeloid Leukemia (AML) diagnosis by leveraging a transfer learning approach from Acute Lymphoblastic Leukemia...

Multimodal AI-driven Biomarker for Early Detection of Cancer Cachexia

Cancer cachexia, a multifactorial metabolic syndrome characterized by severe muscle wasting and weight loss, contributes to poor outcomes across vario...

A Deep Learning Framework for Automated Triage of Breast Cancer Biopsies in Malaysia: A Pragmatic Trial to Reduce Resource Consumption and Diagnostic Turnaround Time

Malaysia faces a significant burden of breast cancer, compounded by a chronic shortage of pathologists. This leads to prolonged diagnostic turnaround ...

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