Oncology/Hematology

Latest AI and machine learning research in oncology/hematology for healthcare professionals.

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Showing 14901-14920 of 19,058 articles

The impact of a SmartPhone applicatiOn for skin cancer risk assessmenT on the healthcare system (SPOT-study): A randomized controlled trial

Artificial intelligence (AI)-based mobile health (mHealth) smartphone apps for skin cancer detection are increasingly available to the general population, but their impact on care is unclear. The SPOT study is an investigator-initiated and -designed, unblinded, randomized controlled trial. Participants from a Dutch non-profit health insurance living in and around region Rotterdam the Netherlands, ...

Prediction of TP53 biomarkers and survival outcomes from whole slide images using a vision transformer-based multi-instance learning framework

Accurate molecular profiling and prognostication from routine histopathology slides could transform precision oncology. We developed a Vision Transformer (ViT)-based multi-instance learning (MIL) framework for combined predictions of 32 solid tumour types, TP53 biomarker detection, and survival prediction directly from Whole Slide Images (WSIs). 11,060 primary tumours were curated from the TCGA Pa...

Uncertainty-Aware Prediction of Microsatellite Instability in Colorectal Cancer from H&E-Stained Whole Slide Images

Microsatellite instability (MSI) is a key biomarker in colorectal cancer (CRC). Accurate distinction between MSI and microsatellite stable (MSS) tumor...

Discrete-Event Simulation Modeling Framework for Cancer Interventions and Population Health in R (DESCIPHR): An Open-Source Pipeline

Simulation models inform health policy decisions by integrating data from multiple sources and forecasting outcomes when there is a lack of comprehens...

Sleep Staging Foundation Models Encode Neural Disorder-Related EEG Representations that Generalize to Wakefulness

To leverage sleep foundation models trained on large datasets of polysomnography for neurological disorder detection during an awake state. Three publ...

GlioMODA: Robust Glioma Segmentation in Clinical Routine

Precise glioma segmentation in MRI is essential for accurate diagnosis, optimal treatment planning, and advancing clinical research. However, most dee...

Patient-Reported Challenges in Lymphoma Diagnosis: Analysis of Online Forum Narratives Using Artificial Intelligence

Lymphoma diagnosis remains challenging due to diverse subtypes and nonspecific presentations. While prior research focused primarily on clinical accur...

Prognostic role of COVID-19 pneumonia signs and other CT-biomarkers for survival in patients with malignant neoplasms: the ARILUS project

Clinically manifested pneumonia associated with COVID-19 infection in cancer patients has been associated with worse prognosis. The prognostic signifi...

Multidisciplinary large language model agent teams for precision oncology enhance complex gynecologic oncology decision support

Large language models can help with clinical decision-making tasks. Complex oncology cases are best managed through multidisciplinary tumor boards but...

Generalizable AI predicts immunotherapy outcomes across cancers and treatments

Immune checkpoint inhibitors have become standard care across many cancers, but most patients do not respond. Predicting response remains challenging ...

Synthesizing Contrast-Enhanced T1 MR Image Using Multiparametric Sequences and Attention to Brain Tumor

The administration of gadolinium-based contrast agents (GBCAs) for acquiring contrast-enhanced T1-weighted magnetic resonance imaging (T1C MRI) is ass...

A multimodal cross-attention pathotranscriptome integration for enhanced survival prediction of oral squamous cell carcinoma

Oral squamous cell carcinoma (OSCC) accounts for a major part of cancer mortality, with survival outcomes highly dependent on early diagnosis. While m...

Integrating Protein-protein Interaction Networks and Machine Learning to Identify Biomarkers of Cancer Onset

Recent large-scale plasma proteomic studies have identified a set of biomarkers for the diagnosis of early cancer onset, but the predictive performanc...

Intraoperative classification of glioblastoma through near real-time stimulated Raman scattering microscopy

Glioblastoma is a highly malignant brain tumor in which maximal safe resection is associated with improved survival, yet the oncological benefit of re...

Learning Patient Similarity from Genomics for Precision Oncology

Precision oncology has informed cancer care by enabling the discovery and application of diagnostic, prognostic, and/or predictive molecular biomarker...

Enhanced Detection Rate of AI for Lung Cancer Detection on GP-Referred Chest X-rays: A Real-World Retrospective Evaluation

To assess whether an artificial intelligence (AI) chest radiograph (CXR) tool could enhance lung cancer detection on primary care–referred CXRs in the...

IHGAMP: Pan-cancer HRD prediction from routine H&E whole-slide images using foundation models

Homologous recombination deficiency (HRD) confers sensitivity to poly (ADP-ribose) polymerase (PARP) inhibitors and platinum-based chemotherapy, repre...

Morphological Landscape Mapping Decodes Pathological Heterogeneity and Proteomic Programs in HCC

Intratumour heterogeneity (ITH) drives the clinical trajectory of HCC, yet routine pathology relies on global classifications that often mask local ar...

LLM-Based Classification of Case Report Abstracts: A Pilot Study on Interactions between Radiotherapy and Systemic Therapies

The growing volume of biomedical literature, especially in oncology, necessitates automated tools for extracting clinically relevant information. Larg...

Data Extraction from Oncology Imaging Reports by Large Language Models: A Comparative Accuracy Study

Manual data extraction from clinical text is resource intensive. Locally hosted large language models (LLMs) may offer a privacy-preserving solution, ...

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