Ophthalmology

Latest AI and machine learning research in ophthalmology for healthcare professionals.

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Synthetic Inducible Bacteria Normalize the Microenvironment of Refractory Tumors, Potentiating Checkpoint Inhibitor Responses.

Immunotherapy has transformed cancer treatment but remains ineffective in many solid tumors, largely due to the immunosuppressive tumor microenvironment (TME). A dense/stiff extracellular matrix (ECM) can hinder immune cell infiltration, limiting therapeutic success. To overcome this challenge, we developed a live biotherapeutic platform using engineered programmable bacteria that offer advantages...

May 18 2026 42145056

Enhancing crop disease recognition framework via vision-language model with cross-attention and gated fusion.

Crop diseases pose a significant threat to agricultural productivity and global food security. Timely and accurate detection of such diseases is crucial for improving both crop yield and quality. While numerous deep learning approaches rely solely on image data for disease identification, they often overlook the complementary value of textual information in enhancing visual analysis. To address th...

May 18 2026 42151330
Automated classification of benign paroxysmal positional vertigo from video-nystagmography using a delay-aware neural network.

Nystagmus is a key indicator of vestibular disorders, including benign paroxysmal positional vertigo (BPPV). Accurate diagnosis of BPPV is essential, ...

May 18 2026 42151355
Genital-prioritized attentional bias in lifelong premature ejaculation: behavioral evidence from eye-tracking and machine learning.

Lifelong premature ejaculation (LPE) involves altered responses to sexual cues. Neuroimaging has identified attention-related neural abnormalities in ...

May 18 2026 42151564
Predictors of the Efficacy of Focused Ultrasound for Moderate-to-Severe Persistent Allergic Rhinitis: A Retrospective Cohort Study.

BACKGROUND: Focused ultrasound (FUS) has achieved favorable results in the treatment of allergic rhinitis (AR). However, some patients still have poor...

May 17 2026 42144291
Exploring dysregulation of cuproptosis-related genes molecular clusters and candidate biomarkers in pterygium.

Pterygium is a common ocular surface disorder, with its prevalence strongly correlated to ultraviolet (UV) exposure in geographic regions. Epidemiolog...

May 16 2026 42143165
STAGE challenge: Structural-Functional Transition in Glaucoma Assessment.

Glaucoma is a leading cause of irreversible yet preventable blindness in working-age populations. Clinical diagnos is currently relies on functional v...

May 15 2026 42143993
Advancing equity in endometrial cancer: A narrative synthesis using a cluster-informed framework for resource-stratified implementation.

Endometrial cancer incidence and mortality are rising globally, disproportionately affecting health systems facing diagnostic, therapeutic, and surviv...

May 15 2026 42138708
Clinical setting-dependent diagnostic accuracy of artificial intelligence and store-and-forward diabetic retinopathy screening: a systematic review and meta-analysis.

Population-based diabetic retinopathy (DR) screening requires diagnostic strategies that optimize clinical utility by balancing missed disease against...

May 15 2026 42141103
Structure-aware retinal disentanglement reveals the genetic architecture of ocular and systemic diseases.

Deep learning effectively extracts retinal phenotypes but often functions as an entangled black box, obscuring specific genetic mechanisms and hinderi...

May 15 2026 42139265
Machine learning-driven identification of circulating biomarkers and therapeutic compounds for diabetic retinopathy.

BACKGROUND: Diabetic retinopathy (DR) is a major cause of severe visual impairment, where early diagnosis and intervention are crucial to prevent irre...

May 14 2026 42129911
Using AI as a teaching partner: enhancing critical thinking and digital literacy in microbiology.

Artificial intelligence (AI) is rapidly reshaping higher education, offering both opportunities and challenges for teaching and learning. As generativ...

May 14 2026 42132399
Analysis of choroidal OCT intensity and profile changes in high myopia: correlation with visual impairment and identification of pathological myopia.

AIMS: To investigate the changes in choroidal optical coherence tomography (OCT) radiomic features, their correlations with visual acuity and utility ...

May 14 2026 42135022
Integrating nano crystal sensor with explainable deep learning for nutrients and microplastic-toxicity detection.

This work proposes a simulation-based photonic-AI sensing framework for soil nutrient and microplastic detection. This framework integrates a 2D dual-...

May 14 2026 42135386
AUBADE-syn: a novel deep learning ensemble method for glaucoma detection using synthetic fundus images on imbalanced datasets.

Glaucoma is the leading cause of irreversible blindness worldwide. Early detection is essential to preserve vision. Deep learning approaches have show...

May 14 2026 42135460
Retinal biological age correlates with bone mineral density and fracture risk score and predicts incident osteoporosis.

Osteoporosis often lacks accessible screening tools, leading to underdiagnosis and increased fracture risk. We explored the potential of a retinal agi...

May 14 2026 42133570
Dynamic brain states and molecular signatures in primary angle-closure glaucoma.

BACKGROUND: Primary angle-closure glaucoma (PACG) has traditionally been regarded as an ocular disorder, but accumulating evidence suggests broader ce...

May 13 2026 42066007
Multimodal artificial intelligence in retinopathy of prematurity: A comprehensive narrative review.

Retinopathy of prematurity (ROP) remains a leading cause of preventable childhood blindness globally, particularly in regions with limited screening r...

May 13 2026 42134610
Carbonic anhydrase under the computational lens: a review of advances, challenges, and future directions.

CONTEXT: Carbonic anhydrases (CAs) are zinc metalloenzymes responsible for the catalysis of the reversible hydration of carbon dioxide and play pivota...

May 13 2026 42126448
Machine learning for risk stratification of postoperative corneal edema in East Asian cataract patients: a model for precision ophthalmology.

PURPOSE: To develop and validate machine learning (ML) models for predicting early postoperative corneal edema (CE) after phacoemulsification in patie...

May 13 2026 42126536
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