Ophthalmology

Manual and automated capture of analgesic-responsive facial pain behaviors of unrestrained mice in a trigeminal neuralgia model.

Trigeminal neuralgia (TN), a devastating neuropathic pain condition, profoundly affects human well-being. Despite an initial response to carbamazepine (CBZ), many patients become refractory to pharmacotherapy and subsequent invasive procedures. Although preclinical trigeminal neuropathic pain models following extracranial chronic constriction injury (CCI) of the trigeminal nerve have been develope...

Research trends and hotspots in robot-assisted ophthalmic surgery: a bibliometric and visualization study.

Robot-assisted ophthalmic surgery has undergone rapid development in recent decades. Robot-assisted ophthalmic surgery, as examined through bibliometric and visual mapping, has its global research status, historical evolution, hotspots, and future trends systematically characterized in this study. Publications related to robot-assisted ophthalmic surgery covered three decades and sourced from the ...

Trace Aqueous Humor Proteome via Macroporous MOF Platform Reveals High-Resolution Molecular Phenotypes of Diabetic Macular Edema.

Diabetic macular edema (DME) is a leading cause of vision impairment worldwide. While aqueous humor (AH) proteomics holds promise for uncovering disea...

A Comparison of Machine Learning and Human Graders for Glaucoma Diagnosis from Fundus Images for Population Screening.

PURPOSE: To compare the accuracy of vertical cup-disc ratios (VCDR), ascertained by machine learning (ML) versus human graders, from fundus images for...

Assessment of Ellipsoid Zone Integrity and Other Quantitative OCT Biomarkers for Intermediate AMD Progression to Atrophy.

PURPOSE: To evaluate the association between baseline optical coherence tomography (OCT) biomarkers and 2-year disease progression from intermediate a...

Comment on: Retinal Age Gap as a Biomarker for Patient Satisfaction and Visual Quality After Cataract Surgery.

Eye-tracking-while-reading: A living survey of datasets with open library support.

Eye-tracking-while-reading corpora are a valuable resource for many different disciplines and use cases. Use cases range from studying the cognitive p...

Do not smile when acquiring consumer selfies for multi-attribute skin profiling and baseline deep learning evaluation.

The increasing demand for personalized skincare solutions highlights a significant gap: many consumers struggle to find suitable products without prof...

Must Every Dental Student Become Digitally Competent? Lessons From Prosthodontic Education in Southeast Asia.

INTRODUCTION: Digital technologies, including intraoral scanners, computer-aided design/computer-aided manufacturing (CAD/CAM), cone-beam computed tom...

Abnormal functional lateralization and cooperation in primary angle-closure glaucoma correlate with cell type-specific transcriptional signatures.

BACKGROUND: Primary angle-closure glaucoma (PACG) damages retinal ganglion cells (RGCs) and is associated with neurodegeneration. This study used rest...

Autism in adolescence and adulthood.

Landmark descriptions of autism in the 1940s were based on clinical work with children. Research over the subsequent 80 years has largely focused on t...

Global research trends in robot-assisted vitreoretinal surgery: a visualized bibliometric analysis.

Robot-assisted vitreoretinal surgery is a precision-oriented approach for technically demanding retinal procedures, but its structure and clinical mat...

Comparative evaluation of large language models and clinicians in real-world glaucoma clinical reasoning.

PURPOSE: Clinical decision-making in glaucoma is complex and requires integration of heterogeneous information, including patient history, examination...

Standardization of Retinal Vasculitis Terminology With Consensus Definitions From a Delphi Panel.

IMPORTANCE: Retinal vasculitis is a sight-threatening condition associated with diverse ocular and systemic diseases. Variability in terminology and d...

PERCEIV: A Multimodal Physiological Dataset of Visual Encodings for Adaptive InfoVis Interfaces.

We contribute PERCEIV (PERCeption of visual Encodings in InfoVis), a large-scale dataset to support studies of user responses to visual encoding varia...

Physician oath, followership and leadership.

Physician oaths are often treated as ceremonial relics or ethical ornaments of graduation. I have come to think they are something more demanding: ear...

An autonomous multimodal AI agent for evidence-grounded ophthalmic diagnosis.

Multimodal ophthalmic diagnosis requires integrating fundus photography, B-scan ultrasonography, and medical evidence, yet most artificial intelligenc...

Comment on "AI in ophthalmology: A bibliometric analysis of retinal imaging innovations and global research collaboration".

Dissecting corneal drug permeability under experimental variability and drug cold-start challenges via hybrid machine learning.

Corneal drug permeability is a key determinant of topical ocular drug delivery efficiency, yet its quantitative prediction remains challenging due to ...

LHR-Net: a lightweight high-resolution network for retinal vessel segmentation.

Retinal vessel segmentation plays a critical role in the diagnosis of ophthalmic diseases. However, challenges arise due to low image contrast and the...