Orthopedics

Latest AI and machine learning research in orthopedics for healthcare professionals.

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Showing 661-680 of 8,094 articles

Artificial intelligence-driven data expansion for the validation of spinopelvic parameter correlations in asymptomatic subjects.

BACKGROUND: The study of spinopelvic alignment in asymptomatic individuals is essential for understanding physiological sagittal balance and establishing reference values for spinal deformity assessment. However, the availability of large datasets of healthy subjects is limited by ethical, logistical, and radiation-related constraints. Artificial intelligence (AI)-based synthetic data generation m...

Jun 2 2026 42228165

ABCA8 drives bone loss via disrupting Th17/Treg imbalance: a novel immunometabolic target for osteoporosis.

BACKGROUND: Osteoporosis is a metabolic bone disease characterized by reduced bone mass and microarchitectural deterioration, with complex involvement of molecular networks and immune-associated transcriptional dysregulation. OBJECTIVE: This study aimed to elucidate the immune-associated regulatory features of ATP-binding cassette subfamily A member 8 (ABCA8) in osteoporosis. METHODS: Differential...

Jun 2 2026 42228211
Large Language Models for Cholesteatoma Diagnosis: A Pathology-Validated Study.

OBJECTIVES: To evaluate the diagnostic performance of the large language model (LLM) Gemini 2.5 for cholesteatoma detection using histopathology as th...

Jun 2 2026 42228449
Assessing the Accuracy and Reliability of ChatGPT-4 to Answer Clinical EHR Messages in Sports Medicine.

OBJECTIVES: Although advancements in electronic health records (EHRs) have improved clinical productivity, digital administrative responsibilities hav...

Jun 2 2026 42229553
AI-derived versus surgeon-performed instrumentation in adolescent idiopathic scoliosis: a biomechanical simulation analysis.

PURPOSE: Posterior spinal fusion (PSF) with pedicle screws is the standard treatment for adolescent idiopathic scoliosis (AIS) with curves > 45°, yet ...

Jun 2 2026 42230526
An explainable machine learning approach to predict fragility fractures and the identification of important features.

In this study, we developed ML algorithms to predict fragility fractures, considering the occurrence of fractures at different skeletal sites, using t...

Jun 2 2026 42230847
A large-scale vision foundation model for musculoskeletal radiographs.

Artificial intelligence (AI) has shown promise in detecting and characterizing musculoskeletal diseases from radiographs. However, most existing model...

Jun 2 2026 42230902
Assessing Military Artificial Intelligence Responses to Anterior Cruciate Ligament Injury Frequently Asked Questions.

INTRODUCTION: Artificial intelligence is gaining significant traction, particularly in the orthopedic literature. To date, there has been no published...

Jun 2 2026 42225552
Large Language Model Hallucinations in Spine Surgery: A Comparative Analysis of Clinician vs Patient-Level Prompts.

BACKGROUND AND OBJECTIVES: Large Language Models (LLMs) are increasingly used by healthcare professionals and patients for medical information synthes...

Jun 2 2026 42232526
Risk stratification for postoperative hematoma following anterior cervical spine surgery: a machine learning approach.

BACKGROUND: Anterior approaches to the cervical spine have consistently increased annually, with commonly performed procedures demonstrating low morbi...

Jun 1 2026 42404488
Continuum damage modeling of fatigue failure in whole bone under combined compression-torsional loading: A hybrid approach with machine learning integration.

Repetitive loading of bone is associated with microdamage accumulation and material property degradation that may ultimately result in fatigue fractur...

Jun 1 2026 42235115
Fractal analysis in dentistry: a bibliometric analysis (1991-2024).

OBJECTIVES: This study aims to provide a comprehensive bibliometric mapping of the scientific evolution and research trends of fractal analysis (FA) i...

Jun 1 2026 42228292
FreeTune4D: Anatomy-Aware 4D-MRI Motion Reconstruction Benchmark and Free Fine-Tuning Framework.

Deep learning and prior-image-guided cross modality motion reconstruction methods have recently en abled faster acquisition time and lower artifacts i...

Jun 1 2026 42224310
Canalization of neural dynamics by δ-protocadherins in the developing zebrafish optic tectum.

Brain dynamics are constrained by the underlying topology of neuronal networks. How genes collaborate to organize these neural networks during develop...

Jun 1 2026 42224358
Deep Learning-Based Bone Age Assessment for Predicting Final Adult Height in Girls With Central Precocious Puberty.

OBJECTIVE: This study aimed to evaluate the accuracy of predicting final adult height (FAH) in Korean girls with central precocious puberty (CPP) usin...

Jun 1 2026 42225576
Integrated Workflow Finite Element Modeling of the Temporomandibular Joint: Toward a Methodical and Reproducible Approach.

This study presents a patient-specific parametric model of the temporomandibular joint, designed to be semi-automated, and reproducible for multiple p...

Jun 1 2026 41893871
The DeepJoint Algorithm: An Innovative Approach for Studying the Longitudinal Evolution of Quantitative Mammographic Density and Its Association With Screen-Detected Breast Cancer Risk.

High mammographic density is a well-known risk factor for breast cancer and reduces the sensitivity of mammography-based screening. While automated ma...

Jun 1 2026 42032926
Numerical Inverse Design of Patient-Specific Dental Implants: Accelerating FEA-Based Optimization via Evolutionary Neural Surrogates.

Mechanical complications in dental implantology often arise from a mismatch between standardized geometries and patient-specific anatomical constraint...

Jun 1 2026 42210774
MedNet-FS: a few-shot learning framework for 3D MRI-based knee injury classification.

The development of deep learning models for 3D knee MRI analysis is critically constrained by the scarcity of large, annotated datasets. Few-shot lear...

May 31 2026 42225724
Deep learning-based CT-derived vertebral bone mineral density and metformin therapy: a longitudinal study in the Multi-Ethnic Study of Atherosclerosis.

OBJECTIVE: Evidence on metformin's skeletal effects remains conflicting. We emulated a target trial to evaluate associations between metformin therapy...

May 31 2026 42218332
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