Orthopedics

Boosting angiogenesis experimentally in ovo by biofunctionalizing collagen membranes with platelet-rich fibrin and hyaluronic acid: implications for regenerative oral surgery?

PURPOSE: Biocompatible collagen membranes (CM) are widely used in regenerative dentistry, particularly in guided tissue regeneration (GTR) and guided bone regeneration (GBR). While resorbable CMs offer advantages such as reduced patient morbidity and enhanced wound healing, their barrier function can impede vascularization, potentially compromising graft survival. Biofunctionalization of CMs with ...

SMGDiff: step mapping generalized diffusion model for efficient noise reduction in cardiac-gated myocardial perfusion SPECT images.

BACKGROUND: Improving the image quality of cardiac gating myocardial perfusion single-photon emission computed tomography (CG MP-SPECT) is crucial for accurate diagnosis. Diffusion model (DM) has recently shown promise in MP-SPECT image denoising, but traditional DM typically require extensive computational resources and prolonged processing times. The study aims to develop and evaluate a lightwei...

Machine learning-based prediction of progression from idiopathic cytopenia of undetermined significance to myeloid malignancies.

Although the risk of progression varies, a subset of patients with idiopathic cytopenia of undetermined significance (ICUS) eventually develop myeloid...

Specification-compliant fracture parameter extraction and rock mass classification on tunnel faces with improved YOLOv8-seg.

Accurate identification of rock mass fractures is essential for evaluating tunnel stability and ensuring construction safety. However, existing deep l...

A randomized controlled trial of a WeChat-based artificial intelligence agent for postoperative care in orthopedic patients.

Effective postoperative management in orthopedic surgery is often hindered by challenges such as poor patient adherence to rehabilitation protocols, i...

Rebuilding the pelvis: advances in robotic-assisted management of complex pelvic fractures.

Complex pelvic fractures are infamously challenging to fix surgically because of their fine anatomy and proximity to vital neurovascular structures. T...

Activating the SDF-1/CXCR4 axis: Notoginsenoside R1-Functionalized zinc scaffolds accelerate fracture healing and angiogenesis in diabetic osteoporosis.

Effective treatment of diabetic osteoporotic fractures (DOF) requires biomaterials capable of promoting vascularized bone regeneration. A biodegradabl...

Intelligent identification of osteoporosis on hip X-rays using vision transformer.

OBJECTIVE: This study aimed to develop and evaluate a deep learning model based on the Vision Transformer (ViT) architecture for the automatic classif...

A Mixed Dual-Branch Network for Detecting Cervical Spondylotic Myelopathy and Parkinsonian Syndromes via Gait Analysis.

Cervical spondylotic myelopathy (CSM) and parkinsonian syndromes (PS) present similar motor symptoms, often causing misdiagnosis due to current clinic...

The Diagnostic Value of Image-Based Machine Learning for Osteoporosis: Systematic Review and Meta-Analysis.

BACKGROUND: Osteoporosis (OP) is projected to be a major issue significantly impacting the well-being of middle-aged and old populations. Machine lear...

Deep learning algorithm for semiquantification of spinal inflammation in axial spondyloarthritis.

OBJECTIVE: To develop a deep learning algorithm for semiquantification of spinal inflammation in patients with axial spondyloarthritis (SpA). METHODS:...

Predicting the progression of difficult-to-treat rheumatoid arthritis by a machine learning scoring system, from the FIRST registry.

OBJECTIVES: This study aimed to develop and validate a prediction model for the future progression of difficult-to-treat rheumatoid arthritis (D2T RA)...

Classifying retinal images via vascular-optic disc cross-segmentation and attentive feature selection.

The prevalence of retinal disorders is rising at an alarming rate, posing a significant risk of irreversible blindness without timely intervention. Re...

Mechanical behaviour of additively manufactured metals.

Additive manufacturing is reshaping the production of engineering components in diverse industries, such as the automotive, aerospace, defence and bio...

Swin Transformer-based intelligent fracture classification and radiographic assessment to support clinical decision-making.

AI-assisted preoperative planning combined with robotic-assisted total knee arthroplasty vs. conventional surgery: a retrospective controlled study.

OBJECTIVE: To compare perioperative outcomes and early functional recovery between AI-robotic and conventional total knee arthroplasty (TKA). METHODS:...

Synovial transcriptome analysis reveals ShenTong ZhuYu Tang alleviates osteoarthritis by targeting MMP-9 and immune microenvironment.

BACKGROUND: This study aimed to elucidate key molecular alterations in the osteoarthritis (OA) synovial microenvironment through transcriptomic analys...

To see or not to see the vet: A vignette-based study of decision-making by UK dog owners regarding seeking veterinary care for commonly presenting conditions.

Barriers to accessing veterinary-care for dog-owners are diverse and dynamic, and widely accepted as major canine welfare threats because of potential...

Quasi-multimodal-based pathophysiological feature learning for retinal disease diagnosis.

Retinal diseases spanning a broad spectrum can be effectively identified and diagnosed using complementary signals from multimodal data. However, mult...

Artificial intelligence-driven clustering for phenotyping life-threatening prehospital trauma.

BACKGROUND: Traumatic patients usually suffer from several complex conditions that hinder their risk characterization. The aim of this study was to de...