Orthopedics

Latest AI and machine learning research in orthopedics for healthcare professionals.

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Showing 1461-1480 of 8,094 articles

Unraveling the Mechanistic Spectrum of Myhre Syndrome: SMAD4 Signaling Disruption, Skeletal Phenotypes, and Translational Innovation.

Myhre syndrome (MYHRS) is an ultra-rare, progressive multisystem disorder caused by recurrent heterozygous missense variants in the SMAD4 gene, a central mediator of TGF-β and BMP signaling. Skeletal abnormalities-including postnatal short stature, brachydactyly, thickened calvarium, and craniofacial dysmorphism-are cardinal features, often accompanied by joint contractures and progressive soft ti...

Feb 8 2026 41656577

TFAP2A transcriptionally regulates B3GALT2 to affect gouty arthritis progression through pyroptosis: a study based on machine learning and multi-omics integration analysis.

BACKGROUND: Gouty arthritis (GA) is an inflammatory joint disease driven by monosodium urate (MSU) crystal deposition. The NOD-like receptor thermal protein domain associated protein 3 (NLRP3) inflammasome-mediated pyroptosis is central to GA pathogenesis, yet potential regulatory targets remain limited. The role of β-1,3-galactosyltransferase 2 (B3GALT2), a glycosyltransferase, is entirely unknow...

Feb 8 2026 41654938
Advances in β-titanium alloys for safer and greener biomedical implants.

In the biomedical field, titanium alloys have long been preferred for orthopedic and dental devices due to their excellent biocompatibility and mechan...

Feb 7 2026 41671924
BackTracker: Machine learning to identify kinematic phenotypes for personalised exercise management in non-specific low back pain.

BACKGROUND: Low back pain (LBP) is a leading cause of global disability. Most cases are non-specific (NSLBP) and lack identifiable causes. Early activ...

Feb 7 2026 41689880
Factors Associated with Machine Learning-Based Predictions of Retinal Aging Using Teleretinal Screening Images from Patients with Diabetes.

PURPOSE: To identify factors associated with accelerated retinal aging based on machine learning predictions of age using fundus images from teleretin...

Feb 7 2026 41853569
CT- DImQ: An open-access platform for image quality assessment of CT systems- application to CT values and noise characterization in 3D-printed anthropomorphic thorax phantoms.

PURPOSE: To present an open access platform for CT image quality assessment combined with anthropomorphic phantoms. To promote the accessibility of an...

Feb 7 2026 41655504
AI-driven 3D virtual surgical planning in total hip arthroplasty: a machine learning approach for precision implant positioning and improved clinical outcomes.

PURPOSE: To explore the clinical significance of the artificial intelligence (AI)-assisted three-dimensional (3D) planning system AI-HIP in total hip ...

Feb 7 2026 41654837
Artificial intelligence for fracture detection on computed tomography: a comprehensive systematic review and meta-analysis of diagnostic test accuracy in non-commercial and commercial solutions.

Rising patient volumes, the increasing use of computed tomography (CT) imaging in emergency departments and the resulting prolonged waiting times high...

Feb 7 2026 41652293
An improved activation function for the recognition of knee osteoarthritis severity.

BACKGROUND: Existing knee osteoarthritis (KOA) severity classification methods typically rely on a combination of object detection algorithms and clas...

Feb 6 2026 41653813
Real-world use of PACS-integrated automated spine numbering in MRI.

PURPOSE: Traditional methods of vertebral identification have predominantly relied on relative approaches, depending on discernible landmarks. Artific...

Feb 6 2026 41666795
Artificial intelligence in virtual fracture clinics: a systematic review of imaging and clinical-text tools.

BACKGROUND: Virtual fracture clinics (VFCs) are a well-established component of acute orthopedic management pathways. Artificial intelligence (AI) hea...

Feb 6 2026 41652489
Prediction of skeletal maturity using machine learning based on multiple biological indicators.

INTRODUCTION: Accurate assessment of skeletal maturity is essential for orthodontic treatment planning and growth modulation. This study aimed to deve...

Feb 6 2026 41653171
The Evolving Role of Musculoskeletal Ultrasound in Gout: From Diagnosis to Management-A Narrative Review.

Gout, a prevalent and treatable form of crystal-induced arthritis, results from monosodium urate (MSU) crystal deposition in articular and periarticul...

Feb 6 2026 41645804
Machine learning model identifies tibial anatomical variables as potential risk factors for anterior cruciate ligament injury.

PURPOSE: The tibial slope is a well-known risk factor for anterior cruciate ligament (ACL) injury. As machine learning continues to progress, it has b...

Feb 6 2026 41649229
Enhancing Anesthetic Depth Assessment via Unsupervised Machine Learning in Processed Electroencephalography Analysis: Novel Methodological Study.

BACKGROUND: General anesthesia comprises 3 essential components-hypnosis, analgesia, and immobility. Among these, maintaining an appropriate hypnotic ...

Feb 6 2026 41650286
Non-coding RNAs as prognostic biomarkers in autoimmune disease.

Autoimmune diseases comprise a broad spectrum of disorders in which both the innate and adaptive branches of the immune system malfunction, mistakenly...

Feb 5 2026 41654009
Open-Source Machine Learning Computed Tomography Scan Segmentation for Spine Osteoporosis Diagnostics.

BACKGROUND AND OBJECTIVES: Dual-energy x-ray absorptiometry (DXA) is the standard for assessing bone mineral density (BMD); however, its accuracy is l...

Feb 5 2026 41641987
Automated diagnostic of cervical spondylosis on multimodal medical images with a multi-task deep learning model.

Cervical spondylosis is one of the most common degenerative diseases, seriously affecting life quality. Unlike diseases with explicit lesions like can...

Feb 5 2026 41644944
SpineWave: Harnessing Fish Rigid-Flexible Spinal Kinematics for Enhancing Biomimetic Robotic Locomotion.

A core soft-robotics challenge for underwater locomotion is reconciling soft actuation's compliance with the control tractability and robustness of ri...

Feb 4 2026 41636779
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