Oncology/Hematology

Other Cancers

Latest AI and machine learning research in other cancers for healthcare professionals.

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Enhancing brain tumor classification with a simplified CNN through hyperparameter optimization.

Brain tumors remain a major public health challenge because of their high mortality rate and the need for timely and accurate diagnosis. Magnetic Resonance Imaging (MRI) is widely used for brain tumor assessment, yet conventional diagnostic workflows still depend largely on the subjective interpretation of radiologists, which may lead to inter-observer variability. In this context, deep learning a...

May 29 2026 42214387

AI-MIRACLE: Artificial Intelligence and MultIpaRAmetric MRI Predict CLinical OutcomEs to Neoadjuvant Immunotherapy in Patients with Muscle-invasive Bladder Cancer Undergoing Radical Cystectomy.

BACKGROUND AND OBJECTIVE: Neoadjuvant immune-checkpoint inhibitors (ICIs) in muscle-invasive bladder cancer (MIBC) were tested in patient's ineligible for cisplatin-based chemotherapy. The PURE-01 trial (NCT02736266) evaluated three courses of pembrolizumab before radical cystectomy (RC). We developed AI-MIRACLE, an international study assessing artificial intelligence (AI) and multiparametric mag...

May 29 2026 42215334
Machine learning based approaches for structure activity relationship analysis of heparanase inhibitors.

Human Heparanase (HPSE), the only mammalian endo-β-D-glucuronidase, plays an important role in extracellular matrix remodeling and the release of hepa...

May 29 2026 42215649
A multimodal interpretable deep learning-radiomics framework for predicting lymph node metastasis following neoadjuvant chemoradiotherapy in locally advanced rectal cancer: a multicenter validation study.

Accurate assessment of lymph node metastasis (LNM) following neoadjuvant chemoradiotherapy (nCRT) presents a significant clinical challenge and is ess...

May 29 2026 42215698
Cyclosporine in hematological disorders: mechanisms, clinical practice and emerging advances.

Cyclosporine A (CsA) functions as a calcineurin inhibitor that perturbs T cell activation via calcineurin-nuclear factor of activated T cells (CaN-NFA...

May 29 2026 42215807
Exercise-related genes predicts overall survival and tumor immune microenvironment, and identifies the biological role of SLC52A2 in breast cancer.

BACKGROUND: Breast cancer (BRCA) is the most common malignant tumor in women, with prognoses differing markedly by molecular subtype. Exercise is know...

May 29 2026 42215809
A novel prognostic model based on MVIRGs identifies ANGPT2 as a key target driving the malignant progression of HCC.

BACKGROUND: Hepatocellular carcinoma (HCC) is a highly lethal malignancy with high recurrence and limited therapies. Microvascular invasion (MVI) is a...

May 29 2026 42215875
The impact of an artificial intelligence (AI)-assisted education program on mental health, social support and quality of life in older individuals with head and neck cancer: study protocol of a randomized controlled trial.

BACKGROUND: Head and neck cancer (HNC) is a common malignant tumor, and its treatment often leads to functional impairments in speech, swallowing, and...

May 29 2026 42215892
MSTM-Net: a two-stage prostate cancer segmentation network based on swin-transformer-mamba architecture.

BACKGROUND: Magnetic resonance imaging (MRI) has become a core imaging modality for prostate cancer screening and diagnosis. Accurate and automatic se...

May 29 2026 42215932
Network toxicology and bioinformatics reveal potential molecular links between cadmium exposure and pancreatic cancer.

BACKGROUND: Environmental cadmium (Cd) pollution poses a severe threat to human health due to its strong bioaccumulation and high carcinogenicity. Alt...

May 29 2026 42216024
DNA damage response signature-based prognostic genes for intrahepatic cholangiocarcinoma: a combined analysis of machine learning and biological experiments.

BACKGROUND: Intrahepatic cholangiocarcinoma (ICC) is a highly aggressive subtype of primary liver cancer with insidious onset, early metastasis, and p...

May 29 2026 42216034
ROI-guided virtual narrow band imaging for laryngeal cancer screening.

White light laryngoscopy is widely available but can miss subtle vascular changes associated with early laryngeal neoplasia. We developed a region-of-...

May 28 2026 42256307
Human factors validation study of an artificial neural network‑based preoperative decision‑support tool for noninvasive lymph node staging (NILS) in women with primary breast cancer (ISRCTN99301435).

BACKGROUND: The integration of clinical decision support tools in medical practice is challenging and must be carefully undertaken, especially in canc...

May 28 2026 42204510
Artificial Intelligence in Hospice and Palliative Care: A Systematic Review of Its Role in Interprofessional Shared Decision-Making Care.

BackgroundArtificial intelligence (AI) is increasingly integrated into hospice and palliative care to support clinical decision-making across clinicia...

May 28 2026 42208020
Quantum-inspired optimization of transformer-capsule networks for accurate brain tumor segmentation and classification.

Brain tumors represent one of the deadliest types of neurological diseases, a fact that makes early accurate diagnosis essential for the survival of p...

May 28 2026 42209605
Lactylation-related prognostic signature characterized in pancreatic ductal adenocarcinoma through public scRNA-seq dataset and machine learning algorithms: the TOP2A-H3K18la-NQO1 axis orchestrates malignant progression.

BACKGROUND: Lactate promotes histone lactylation, which affects protein transcription and translation, thereby influencing tumour cell progression. Ho...

May 28 2026 42209673
Artificial intelligence in cancer immunotherapy: current trends in predicting response and personalizing treatment.

Artificial intelligence (AI) can transform cancer immunotherapy by enabling more accurate prediction of treatment responses, the discovery of specific...

May 28 2026 42209845
Artificial intelligence and transforming cancer care.

Artificial Intelligence (AI) is reshaping oncology by addressing key limitations in traditional cancer care and enabling data-driven, personalized app...

May 28 2026 42209847
Colorectal cancer sidedness: prognostic implications and the predictive role of artificial intelligence.

BACKGROUND: Colorectal cancer (CRC) is a biologically heterogeneous disease in which tumor sidedness has emerged as a relevant prognostic factor. Conv...

May 28 2026 42210356
Assessing biomarkers for patients with breast cancer who are suited for adjuvant therapy.

INTRODUCTION: Biomarker-guided stratification is essential for optimizing adjuvant systemic therapy in early-stage breast cancer, requiring a balance ...

May 28 2026 42210689
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