Other Cancers

Radiomics of Dynamic Contrast-Enhanced MRI for Predicting Radiation-Induced Hepatic Toxicity After Intensity Modulated Radiotherapy for Hepatocellular Carcinoma: A Machine Learning Predictive Model Based on the SHAP Methodology.

OBJECTIVE: To develop an interpretable machine learning (ML) model using dynamic contrast-enhanced m...

Automated determination of tumor cell percentages in whole slide images: A nuclear classification study for molecular pathology tests.

Calculation of tumor cell percentage, a critical pre-analytical component in molecular pathology, is...

Artificial intelligence-assisted CT radiomics: redefining preoperative prediction of lateral cervical lymph node metastasis in papillary thyroid carcinoma.

Fibrogenesis-driven tumor progression in clear cell renal cell carcinoma: prognostic, therapeutic implications and the dual role of neuropilin-1.

BACKGROUND: Clear cell renal cell carcinoma (ccRCC) is the predominant subtype of renal cancer, with...

Comparing methods to improve cone-beam computed tomography for dose calculations in adaptive proton therapy.

BACKGROUND AND PURPOSE: Proton therapy requires dose monitoring, often performed based on repeated c...

MRI Radiomics to Predict Early Treatment Response to TACE Combined with Lenvatinib Plus a PD-1 Inhibitor for Hepatocellular Carcinoma with Portal Vein Tumor Thrombus.

PURPOSE: To develop and validate a predictor for early treatment response in hepatocellular carcinom...

Deciphering the Immunomodulatory Function of GSN Inflammatory Cancer-Associated Fibroblasts in Renal Cell Carcinoma Immunotherapy: Insights From Pan-Cancer Single-Cell Landscape and Spatial Transcriptomics Analysis.

The heterogeneity of cancer-associated fibroblasts (CAFs) could affect the response to immune checkp...

A novel model for predicting immunotherapy response and prognosis in NSCLC patients.

BACKGROUND: How to screen beneficiary populations has always been a clinical challenge in the treatm...

Deciphering Shared Gene Signatures and Immune Infiltration Characteristics Between Gestational Diabetes Mellitus and Preeclampsia by Integrated Bioinformatics Analysis and Machine Learning.

Gestational diabetes mellitus (GDM) and preeclampsia (PE) are common and serious disorders of pregna...

Tumor budding and poorly differentiated clusters as a biological continuum in colorectal cancer invasion and prognosis.

Tumor budding (TB) and poorly differentiated clusters (PDCs) are features of infiltrative growth pat...

Predicting Immunotherapy Response in Unresectable Hepatocellular Carcinoma: A Comparative Study of Large Language Models and Human Experts.

Hepatocellular carcinoma (HCC) is an aggressive cancer with limited biomarkers for predicting immuno...

Comparison of Manual Versus QuPath Software-based Immunohistochemical Scoring Using Oral Squamous Cell Carcinoma as a Model.

Gold standard for immunohistochemical analyses is the manual assessment by two specialist pathologis...

Development of a chitosanase 3-like protein 1 assay kit and study of its application in patients with hepatocellular carcinoma.

OBJECTIVE: The detection kit for plasma Chitinase-3-like Protein 1 was developed using the magnetic ...

A potential new strategy for BC treatment: NPs containing solanine and evaluation of its anticancer and antimetastatic properties.

Solanine has been shown to inhibit cancer by regulating the expression of apoptosis (Bax, Bcl-2) and...

Cocaine-Induced Apoplexy of a GH-Secreting Pituitary Tumor.

A 25-year-old previously healthy man presents to the clinic with a severe headache after cocaine con...

From Multi-Omics to Visualization and Beyond: Bridging Micro and Macro Insights in CAR-T Cell Therapy.

Chimeric antigen receptor T (CAR-T) cell therapies, a cornerstone of immunotherapy, have demonstrate...

Modified albumin-bilirubin grade and alpha-fetoprotein score for predicting prognosis of hepatocellular carcinoma patients undergoing conventional transarterial chemoembolization.

BACKGROUND: Predicting post-treatment prognosis in hepatocellular carcinoma (HCC) patients undergoin...

Pien Tze Huang Attenuates Cell Proliferation and Stemness Promoted by miR-483-5p in Hepatocellular Carcinoma Cells.

OBJECTIVE: To investigate the effect of miR-483-5p on hepatocellular carcinoma (HCC) cells prolifera...

Isolation and characterization of a bioactive compound from Sphingomonas sanguinis DM with cytotoxic and molecular docking analysis.

Datura metel, a common plant in the Solanaceae family, is known for its valuable medicinal propertie...

Efficacy and safety of first-line CDK4/6 inhibitors plus AI therapy for patients with HR +/HER2- advanced breast cancer: a network meta-analysis.

BACKGROUND: CDK4/6 inhibitors plus aromatase inhibitors (AI) significantly improve the therapeutic e...

The role of nanomedicine and artificial intelligence in cancer health care: individual applications and emerging integrations-a narrative review.

Cancer remains one of the deadliest diseases globally, significantly impacting patients' quality of ...