Other Cancers

Liquid biopsy biomarkers for accurate detection of malignant pulmonary nodules: a meta-analytic approach.

UNLABELLED: Pulmonary nodules are a common radiological finding that can be classified as either ben...

Pathology of peripheral neuroblastic tumors.

Neuroblastoma is the most prevalent extracranial solid tumor in pediatric age populations worldwide ...

Dual-layer spectral detector computed tomography multiparameter machine learning model for prediction of lymph node metastases in esophageal squamous cell carcinoma.

From inhibition to regulation: serpins in health and disease.

This issue of the Biomedical Journal highlights regulatory mechanisms that shape aging, disease prog...

Organ preservation in rectal cancer: an endoscopist's perspective on current evidence and future directions.

Rectal cancer management has increasingly shifted toward organ-preserving strategies that aim to mai...

An explainable AI workflow integrating automated volumetric body composition analysis for predicting pathological grading of gastroenteropancreatic neuroendocrine neoplasms: a multicenter cohort study.

BACKGROUND: Gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs) are heterogeneous tumors with...

Unraveling heterogeneity in LUAD via multi-omics integration: molecular classification and therapeutic implications.

Lung adenocarcinoma (LUAD) displays significant morphological and molecular heterogeneity both withi...

Differentiation of focal liver lesions in contrast-enhanced ultrasound using a heuristic-guided hybrid machine-learning framework.

PURPOSE: Sonazoid contrast-enhanced ultrasound (CEUS) offers valuable diagnostic information on hepa...

Multi-omics deep learning improves FDG PET-CT-based long-term prognostication of breast cancer.

[18F] fluorodeoxyglucose positron emission tomography - computed tomography (FDG PET-CT) is increasi...

Construction of a risk model based on exosome-related genes predict clinical prognosis and therapeutic response and revealing TIMP1 as a promising target in colorectal cancer.

Various exosome-derived proteins have been reported to play essential roles in regulating colorectal...

Radiomics-based gradient boosting model on contrast-enhanced MRI for non-invasive prediction of epidermal growth factor receptor expression and therapeutic response to EGFR-targeted antibody-drug conjugates in high-grade glioma organoid models.

BACKGROUND: Epidermal growth factor (EGF) and its receptor EGF(EGFR) play crucial roles in glioblast...

Development and Validation of a Machine Learning Model for Dementia Staging in a Heterogeneous Cognitive Impairment Cohort Using Multimodal Features.

RATIONALE AND OBJECTIVES: With the emergence of disease-modifying therapies, precise staging of deme...

A navigation-guided 3D breast ultrasound scanning and reconstruction system for automated multi-lesion spatial localization and diagnosis.

Handheld ultrasound (HHUS) is indispensable for breast cancer screening but remains compromised by o...

Multimodal sparse fusion transformer network with spatio-temporal decoupling for breast tumor classification.

Accurate analysis of tumor morphology, vascularity, and tissue stiffness under multimodal ultrasound...

Clinically aligned whole-body MRI segmentation of skeletal metastases via Supervised Anatomical Pretraining.

In oncology practice, response assessment of metastatic disease requires reliable and reproducible q...

Automated 3D body composition analysis on chest CT scans for survival prediction in high-grade extremity soft tissue sarcomas.

INTRODUCTION: High-grade soft tissue sarcomas (STShg) of the extremities are rare cancers with a poo...

The seeds of the future are in the present: A blind exploration of metastable states.

In this work, we present a type of molecular dynamics simulation that aims at finding, in a blind wa...

Decrypting potential mechanisms linking ochratoxin A to hepatocellular carcinoma: an integrated approach combining toxicology, machine learning, molecular docking, and molecular dynamics simulation.

BACKGROUND: Ochratoxin A (OTA), a common food-borne mycotoxin, is a potential human carcinogen, yet ...

Engineering Immune Cell to Counteract Aging and Aging-Associated Diseases.

Aging and age-related diseases are a major public health concern, driving interest in anti-aging res...

Advanced immunotherapy across diseases and the role of artificial intelligence: A review.

Immunotherapy, a therapeutic strategy aimed at modulating the host immune system, has undergone rapi...

18F-FDG PET radiomics model for predicting TARE response in patients with colorectal cancer liver metastases.

PURPOSE: Predicting treatment response in patients with colorectal cancer liver metastases (CRCLM) w...