Oncology/Hematology

Other Cancers

Latest AI and machine learning research in other cancers for healthcare professionals.

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Dissecting glioblastoma risk signatures in the tumor immune microenvironment based on multi-dimensional transcriptomics.

Glioblastoma (GBM) is characterized by pronounced tumor heterogeneity and a complex immune microenvironment, contributing to poor patient survival outcomes. In this study, we comprehensively dissected the tumor microenvironment (TME) and uncovered potential molecular mechanisms by integrating single-cell, bulk, and spatial transcriptomic data. Hallmarks of malignancy and cell cycle regulatory path...

Mar 25 2026 41880523

[Comprehensive diagnosis and treatment of distal biliary strictures: multidisciplinary collaboration and precision surgical strategies].

Distal biliary strictures (DBS) are a common and complex clinical problem in pancreaticobiliary diseases,with etiologies involving multiple factors such as inflammation,benign fibrous strictures,and malignant tumors. Differentiating between benign and malignant DBS is challenging,and clinical decision-making often requires a collaborative approach involving imaging,endoscopic techniques,histopatho...

Mar 25 2026 41881790
Artificial intelligence for detection, grading, and prognostication in prostate cancer pathology: A scoping review.

Artificial intelligence (AI) has been transforming many aspects of medical care. In prostate cancer, ongoing progress in AI has improved research and ...

Mar 25 2026 41808601
A convolutional neural network for fully automated total metabolic tumor volume delineation in patients with aggressive Non-Hodgkin lymphoma.

PURPOSE: The [18F]FDG-PET-derived total metabolic tumor volume (TMTV) has a high prognostic value in patients with Hodgkin and Non-Hodgkin lymphoma. H...

Mar 24 2026 41872336
Development of hematopoietic stem cell-targeted lipid nanoparticles through lipid composition optimization.

Hematopoietic stem cell (HSC)-targeted gene editing holds significant potential for treating hereditary hematopoietic disorders, yet the efficient and...

Mar 24 2026 41887390
Machine learning vs. radiomics for discriminating atypical cartilaginous tumors from benign enchondromas on MRI.

BACKGROUND: Enchondromas (EC) present cartilaginous tumors that are difficult to differentiate from their intermediate counterpart, atypical cartilagi...

Mar 24 2026 41877085
Harnessing the gut microbiota in extra-intestinal cancers: from causal evidence to immunotherapy strategies.

The gut microbiota (GM) has emerged as a key modulator of cancer development and therapeutic response beyond the gastrointestinal tract. In extra-inte...

Mar 24 2026 41873461
Artificial intelligence and radiomics in bladder cancer MRI: a scoping review of applications, performance, and barriers to clinical translation.

Artificial intelligence (AI) and radiomics show significant potential to augment bladder cancer (BC) MRI but face a critical translational gap. This s...

Mar 24 2026 41874614
Deep learning reconstruction enables accelerated T2-weighted MRI for rectal cancer staging: a prospective study of diagnostic consistency across NEX value reduction.

OBJECTIVES: To evaluate the image quality, interpretation consistency, and scanning efficiency of deep learning-based reconstruction (DLR) algorithm (...

Mar 24 2026 41874617
Thrombopoietin receptor agonists in immune thrombocytopenia: a comparative review of mechanisms, efficacy, and the future of personalized management.

INTRODUCTION: Thrombopoietin receptor agonists (TPO-RAs) have reshaped the management of chronic immune thrombocytopenia (ITP) by directly targeting i...

Mar 24 2026 41875247
Negligible impact of perifissural nodules in an AI-first reader workflow from UK lung screening trial.

OBJECTIVE: To evaluate the effect of perifissural nodules (PFNs) on radiologist workload within an AI-first reader workflow for lung cancer screening,...

Mar 23 2026 41872344
Explainable AI for gastrointestinal lesion surveillance and precision targeted drug delivery.

The Internet of Bio-NanoThings (IoBNT) promises revolutionary healthcare applications, particularly in targeted drug delivery. However, major challeng...

Mar 23 2026 41872672
TCR recognition of peptide-HLA class II complexes in autoimmunity: Structural insights for therapeutic targeting.

Autoimmune diseases encompass a broad spectrum of disorders in which self-reactive T and B cells breach immune tolerance and drive chronic tissue infl...

Mar 23 2026 41875606
Predicting early clinical recovery in first-episode psychosis: development and external validation of a clinically interpretable multivariable model.

BACKGROUND: Identifying patients with first-episode psychosis (FEP) who are unlikely to achieve early clinical recovery (ECR) is critical for personal...

Mar 23 2026 41867014
Comprehensive multi omics profiling and Mendelian randomization assessment of lipid metabolites in lung cancer prognosis.

BACKGROUND: Lung cancer remains the leading cause of cancer-related mortality worldwide. This study aimed to develop prognostic prediction models for ...

Mar 23 2026 41870745
Integrated single-cell and spatial mapping coupled with machine learning unveils core stemness landscapes and regulatory drivers in triple-negative breast cancer.

OBJECTIVE: Triple-negative breast cancer (TNBC) exhibits pronounced intratumoral heterogeneity, and cancer stem cells (CSCs) are thought to play a piv...

Mar 23 2026 41870799
Stage-dependent gut microbiome and functional signatures across the liver disease spectrum: an integrative multicohort study.

BACKGROUND: The gut-liver axis plays a critical role in liver disease progression; however, how gut microbial ecology and function vary across disease...

Mar 23 2026 41871945
Digital twin technologies for supporting self-care in adults with diet-related chronic conditions: a systematic review.

BACKGROUND: Diet-related chronic conditions are major contributors to global morbidity and mortality. Effective management of these conditions require...

Mar 22 2026 41880918
LLM-powered prostate cancer staging from PSMA-PET/CT reports using PROMISE v2.

Accurate staging of prostate cancer is essential for guiding therapy and predicting outcomes. Prostate-specific membrane antigen (PSMA) PET/CT has bec...

Mar 21 2026 41863604
Precision oncology meets nanotechnology: AI-driven liposomal nanocarriers for enhanced cancer immunotherapy.

The integration of artificial intelligence (AI) with nanotechnology is redefining therapeutic strategies in cancer immunotherapy and chemotherapy. The...

Mar 21 2026 41871725
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