Oncology/Hematology

Other Cancers

Latest AI and machine learning research in other cancers for healthcare professionals.

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Precision immunotherapies for systemic lupus erythematosus: From pathogenic targets to translational horizons.

Systemic lupus erythematosus (SLE) is a heterogeneous autoimmune disorder in which aberrant B-cell activation, persistent autoantibody production, and dysregulated cytokine and intracellular signaling networks converge to produce relapsing-remitting, multisystem inflammation and cumulative organ damage. Although conventional immunosuppressants remain the backbone of care and can attenuate disease ...

Mar 9 2026 41812738

Predictive biomarkers of response to chimeric antigen receptor (CAR) T-cell therapy for pan-haematologic cancer.

Chimeric antigen receptor (CAR) T-cell therapy holds great promise for patients with cancer, and the identification of predictive biomarkers is crucial in finding new ways to guide therapy. Major challenges to the application of informatics and machine learning in CAR T-cell therapy include limited sample sizes and non-uniformity in data generation across cancer indications and trials. Here we too...

Mar 9 2026 41803255
Multiphase CT-based deep learning radiomics nomogram models for preoperative WHO/ISUP grading of clear cell renal cell carcinoma: a two-center validation study.

BACKGROUND: Preoperative determination of clear cell renal cell carcinoma (ccRCC) World Health Organization/International Society of Urological Pathol...

Mar 9 2026 41803747
SMC4/SMAD3/NF-κB axis drives cervical cancer progression and radioresistance via DNA damage repair and immune modulation.

OBJECTIVE: Cervical cancer remains a significant global health burden, with the molecular determinants of its progression and therapeutic resistance n...

Mar 9 2026 41803949
Revolutionizing hepatic fibrosis staging: A machine learning approach combining clinical, biochemical, and microbiome insights.

Non-alcoholic Steatohepatitis (NASH) is a common disease that not only affects adults but has also been seen to affect all ages. This includes young a...

Mar 9 2026 41806697
Dysbiosis of fecal virome in pediatric Crohn's disease and its dynamic changes during infliximab therapy.

UNLABELLED: The gut virome is an emerging but underexplored component of the human microbiota, especially in pediatric Crohn's disease (CD). This stud...

Mar 9 2026 41800893
Effect of a Computer-Aided Device for Detecting Gastric Neoplasms: A Multicenter, Randomized Controlled Trial.

BACKGROUND & AIMS: Evidence about the effect of artificial intelligence (AI) on upper endoscopy in multicenter, randomized controlled trials is lackin...

Mar 9 2026 41801173
Development and validation of an interpretable MRI-based multimodal fusion model for predicting lymph node metastasis after neoadjuvant chemoradiotherapy in locally advanced rectal cancer: a multicenter study.

OBJECTIVE: To develop an interpretable multimodal model that integrates pre-treatment Magnetic resonance imaging (MRI)-based deep learning radiomics (...

Mar 9 2026 41801383
Prognostic Significance and Immune Landscape of Migrasome-Related Genes in Pancreatic Cancer.

Pancreatic cancer is characterized by early metastasis and high aggressiveness, highlighting the need for novel molecular biomarkers to improve progno...

Mar 9 2026 41801554
The prevalence and clinical significance of clonal monocytosis.

The terms clonal monocytosis of undetermined significance (CMUS) and clonal cytopenia and monocytosis of undetermined significance (CCMUS) were introd...

Mar 9 2026 41802133
Combined hepatocellular-cholangiocarcinoma: a contemporary pathologic and molecular perspective.

Combined hepatocellular cholangiocarcinoma (cHCC-CCA) is a rare primary liver carcinoma characterized by the unequivocal coexistence of hepatocytic an...

Mar 9 2026 41802450
Identification of core genes mediating the association between obesity and hepatocellular carcinoma: A bioinformatics study based on mitochondrial metabolism and immune pathways.

PURPOSE: Obesity is strongly associated with hepatocellular carcinoma (HCC), yet the molecular mechanisms linking them remain unclear. This study aime...

Mar 9 2026 41801960
Epitranscriptomic signatures of malignancy: how RNA modifications shape breast and ovarian tumor progression.

Breast and ovarian cancers are still one of the most prevalent causes of cancer death among the women in all parts of the world, mostly occurring at a...

Mar 8 2026 41806930
Tumor burden in metastatic colorectal cancer quantified using deep learning models: Prognostic value and maintenance treatment benefit in the CAIRO3 trial.

INTRODUCTION: Total tumor number (TTN) and total tumor volume (TTV) reflect tumor burden and have been linked to outcomes in metastatic colorectal can...

Mar 7 2026 41819026
Increased Prevalence of Extrathymic Neoplasms in Myasthenia Gravis Patients-A Population-Based, Matched Case-Control Study.

INTRODUCTION/AIMS: Myasthenia gravis (MG) is associated with thymic neoplasms. However, an increased prevalence of extrathymic neoplasms has also been...

Mar 7 2026 41795172
Deep Learning Reconstruction on Quantitative Analysis in Brain Tumors With Diffusion-Weighted Imaging and Dynamic Susceptibility Contrast Imaging.

BACKGROUND: Although deep learning reconstruction (DLR) has been shown to improve image quality in MRI, its impact on quantitative physiologic paramet...

Mar 7 2026 41793218
Adaptive diagnostic reasoning framework for pathology with multimodal large language models.

BACKGROUND: Artificial intelligence enhances pathology screening efficiency, yet clinical adoption remains limited because most systems operate as opa...

Mar 7 2026 41794962
Combining AI to reveal CCDC3-mediated pathways of colorectal cancer liver metastasis.

In colorectal cancer liver metastases, chromosomal instability (CIN) serves as a critical hallmark linked to tumor aggressiveness and poor prognosis. ...

Mar 7 2026 41792471
Role of the gut microbiome in shaping drug response in immunocompromised hosts.

BACKGROUND: There is an increasing amount of evidence on microbiome-drug interactions in several clinical settings, including in immunocompromised pat...

Mar 6 2026 41796961
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