Oncology/Hematology

Other Cancers

Latest AI and machine learning research in other cancers for healthcare professionals.

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Graph adiabatic diffusion neural networks for distribution-shift breast tumor image classification.

Breast tumor images show low intra-class similarity and suffer from distribution shift, posing challenges for recognition tasks. While increasing the number of labeled training data is a common strategy to improve performance, the high cost of expert annotation is another challenge. Semi-supervised learning methods, e.g., Graph Neural Networks (GNNs), which smooth features via graph topology, have...

Feb 6 2026 41707484

ALKBH5 orchestrates ferroptosis-driven tumor suppression: An LLM-powered discovery in prostate cancer.

The treatment of prostate cancer (PCa) continues to pose substantial clinical challenges. The use of large language models (LLMs) to identify the key molecular determinants of PCa progression, followed by experimental biological validation, helps uncover novel therapeutic targets. We developed hierarchical knowledge-guided LLM for risk gene identification (HKLLM-RG), a PCa risk gene identification...

Feb 6 2026 41655016
Application of radiomics in head and neck squamous cell carcinoma.

Head and neck squamous cell carcinoma (HNSCC) is the most prevalent histopathological subtype of head and neck malignancies. Owing to the lack of earl...

Feb 6 2026 41655558
From wrinkles to malignancy: small-molecule-mediated stem cell approaches in skin aging.

Skin aging is driven by the progressive exhaustion of stem cell niches, epigenetic drift, and accumulation of senescent cells, which together promote ...

Feb 6 2026 41655728
Sequential glioblastoma segmentation via topological data analysis and spatial adjacency.

Segmenting glioblastoma in medical imaging remains challenging due to the tumor's irregular shape, heterogeneous texture, and poorly defined boundarie...

Feb 6 2026 41604711
Multidisciplinary Team Diagnosis and Treatment of well-differentiated thyroid carcinoma: Current Landscape and Future Prospects.

BACKGROUND: The incidence of thyroid cancer has increased markedly in recent years, largely driven by well-differentiated thyroid carcinoma (WDTC). WD...

Feb 6 2026 41652888
Protocol for non-invasive tumor monitoring and diagnosis based on interpretable deep learning.

Tumor-specific DNA methylation profiling in plasma cell-free DNA (cfDNA) offers a promising approach for non-invasive tumor detection. Here, we presen...

Feb 6 2026 41653437
Screening for Tumor Microtube-Targeting Drugs Identifies PKC Modulators as Multipotent Inhibitors of Glioblastoma Progression.

UNLABELLED: Glioblastomas are incurable primary brain tumors that depend on neural-like cellular processes, tumor microtubes (TM), to invade the brain...

Feb 6 2026 41065276
Synergistic DBNDD1-GDF15 Signaling Activates the NF-κB Pathway to Promote Colorectal Cancer Progression.

UNLABELLED: Colorectal cancer is a highly lethal gastrointestinal tract malignancy whose pathogenesis and molecular drivers are not fully understood. ...

Feb 6 2026 41182793
Machine Learning Models for Posttransplant Lymphoproliferative Disorder (PTLD) Risk Prediction in Thoracic Transplantation.

Posttransplant lymphoproliferative disorder (PTLD) is the second most common malignancy in thoracic transplant recipients and is associated with poor ...

Feb 6 2026 41645392
Implementation of artificial intelligence in palliative and supportive care for people with cancer: A scoping review.

BACKGROUND: Cancer remains a leading global health burden. Artificial intelligence offers new opportunities to address complex physical and psychologi...

Feb 6 2026 41645881
Mamba-based Deep Learning Approach for Sleep Staging on a Wireless Multimodal Wearable System Without Electroencephalography.

STUDY OBJECTIVES: We investigate a Mamba-based deep learning approach for sleep staging on signals from ANNE One (Sibel Health, Chicago, IL), a non-in...

Feb 6 2026 41649157
AI-FLEET: Phase I-Multimodal Deep Learning Model for Phyllodes Tumor Classification.

BACKGROUND: Fibroepithelial breast lesions, including fibroadenomas and phyllodes tumors (PTs), can be difficult to classify on needle biopsy. Misclas...

Feb 6 2026 41649783
A High Magnifications Histopathology Image Dataset for Oral Squamous Cell Carcinoma Diagnosis and Prognosis.

Oral Squamous Cell Carcinoma (OSCC) is a prevalent and aggressive malignancy where deep learning-based computer-aided diagnosis and prognosis can enha...

Feb 6 2026 41651871
Intraoperative biopsy imaging of lung cancer risk.

BACKGROUND: Before surgical resection of lung tumor, intraoperative biopsy is needed for cancer diagnosis, while current techniques that guide biopsy ...

Feb 6 2026 41651970
STAR (stroma-tumor AI risk) assessment: association of AI-derived tumor-stroma proportion with patient survival provides added prognostic value beyond KELIM in epithelial ovarian cancer.

BACKGROUND: There remains a critical need for prognostic biomarkers of treatment response in epithelial ovarian cancer (EOC). The KELIM score, derived...

Feb 6 2026 41652007
Label-free serum SERS combined with RFE-GBDT algorithm for non-invasive screening of liver cancer.

Early diagnosis of liver cancer is crucial for developing clinical treatment strategies and improving patient survival rates. However, current diagnos...

Feb 5 2026 41662803
CT-based radiomics for predicting PD-L1 expression status in non-small cell lung cancer using a hybrid machine learning model.

PURPOSE: Programmed cell death ligand-1 (PD-L1) is a key prognostic and predictive biomarker for immunotherapy in non-small cell lung cancer (NSCLC). ...

Feb 5 2026 41690021
Stochasticity in cancer immunotherapy stems from rare but functionally critical Spark T cells.

Cancer immunotherapies trigger highly variable responses in patients and in genetically identical mouse models. To assess the intrinsic stochasticity ...

Feb 5 2026 41650970
Extracellular vesicles in colorectal cancer: immunomodulation, diagnostics, and therapeutic perspectives.

Colorectal cancer (CRC) remains a significant global health concern and is among the leading causes of cancer-related mortality. The disease often pro...

Feb 5 2026 41642383
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