Pain Management

Latest AI and machine learning research in pain management for healthcare professionals.

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Images in Sentences: Scaling Interleaved Instructions for Unified Visual Generation

While recent advancements in multimodal language models have enabled image generation from expressive multi-image instructions, existing methods struggle to maintain performance under complex interleaved instructions. This limitation stems from the structural separation of images and text in current paradigms, which forces models to bridge difficult long-range dependencies to match descriptions wi...

May 12 2026 2605.12305v1

Prompt-engineering improves clinical safety of large language models for opioid equipotency conversion

Background: Large language models (LLMs) are increasingly used in medical education and clinical decision-making, but their reliability in high-risk medication dosing remains unclear. Opioid rotation is a common task requiring precise calculations where errors may result in overdose or inadequate pain relief. Methods: Thirteen LLMs were tested using an API-based framework to ensure independent que...

A widespread internal brain state for fentanyl withdrawal

Opioid addiction is characterized by escalating drug use, driven in part by negative reinforcement from withdrawal, but the neural processes linking w...

TRACED: In vivo imaging of extracellular intrinsic diffusivity, tortuosity, cell size distribution and cell density in human glioma patients

The lack of analytical models describing diffusion time dependence at intermediate time scales in complex tissue microstructure limits the accurate qu...

May 4 2026 2605.02615v1
A biologically annotated neural network for proteomic discovery in Parkinsons disease

Machine learning models that can utilize high-dimensional data to make predictions and derive biological insights can improve understanding of disease...

Predicting one-year postoperative functional status in contrast-enhancing glioma

Background and Objectives Preoperative prediction of functional outcomes in contrast-enhancing glioma could support surgical decision-making and patie...

A Data-Centric Framework for Intraoperative Fluorescence Lifetime Imaging for Glioma Surgical Guidance

Accurate intraoperative assessment of glioma infiltration is essential for maximizing tumor resection while preserving functional brain tissue. Fluore...

Apr 28 2026 2604.26147v1
Exploring Remote Photoplethysmography for Neonatal Pain Detection from Facial Videos

Unaddressed pain in neonates can lead to adverse effects, including delayed development and slower weight gain, emphasising the need for more objectiv...

Apr 28 2026 2604.25680v1
Psychologically-Grounded Graph Modeling for Interpretable Depression Detection

Automatic depression detection from conversational interactions holds significant promise for scalable screening but remains hindered by severe data s...

Apr 27 2026 2604.24126v1
ZID-Net: Zero-Inference Diffusion Prior Decoupling Network for Single Image Dehazing

Single image dehazing is often constrained by a trade-off between restoration quality and computational efficiency. While efficient, CNN networks stru...

Apr 26 2026 2604.23709v1
Recovering Clinical Detail in AI-Generated Responses for Low Back Pain Through Prompt Design

Introduction Large language models are increasingly being used in healthcare. In interventional pain medicine, clinical reasoning is essential for pro...

Dual Causal Inference: Integrating Backdoor Adjustment and Instrumental Variable Learning for Medical VQA

Medical Visual Question Answering (MedVQA) aims to generate clinically reliable answers conditioned on complex medical images and questions. However, ...

Apr 22 2026 2604.20306v1
Hero-Mamba: Mamba-based Dual Domain Learning for Underwater Image Enhancement

Underwater images often suffer from severe degradation, such as color distortion, low contrast, and blurred details, due to light absorption and scatt...

Apr 17 2026 2604.16266v1
Knowing When Not to Answer: Evaluating Abstention in Multimodal Reasoning Systems

Effective abstention (EA), recognizing evidence insufficiency and refraining from answering, is critical for reliable multimodal systems. Yet existing...

Apr 16 2026 2604.14799v1
Reinforcement learning for closed-loop optimisation of spatiotemporal stimulation in patterned neuronal networks

Understanding how neuronal circuits transform inputs into outputs requires systematic perturbation under controlled conditions. In vitro neuronal netw...

No One Left Behind: Adaptive Tablet Modalities for Digitally Excluded Emergency Department Patients Design, Implementation, and Social Evidence for an Impairment-First Interface

Background: The urgent care departments in Europe face a structural paradox: accelerating digitalisation is accompanied by a patient population that i...

Pseudo-Unification: Entropy Probing Reveals Divergent Information Patterns in Unified Multimodal Models

Unified multimodal models (UMMs) were designed to combine the reasoning ability of large language models (LLMs) with the generation capability of visi...

Apr 13 2026 2604.10949v1
Test-time Scaling over Perception: Resolving the Grounding Paradox in Thinking with Images

Recent multimodal large language models (MLLMs) have begun to support Thinking with Images by invoking visual tools such as zooming and cropping durin...

Apr 13 2026 2604.11025v1
CIR: Lightweight Container Image for Cross-Platform Deployment

In modern cloud and heterogeneous distributed infrastructures, container images are widely used as the deployment unit for machine learning applicatio...

Apr 12 2026 2604.10411v1
Mosaic: Multimodal Jailbreak against Closed-Source VLMs via Multi-View Ensemble Optimization

Vision-Language Models (VLMs) are powerful but remain vulnerable to multimodal jailbreak attacks. Existing attacks mainly rely on either explicit visu...

Apr 10 2026 2604.09253v1
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