Latest AI and machine learning research in pathology for healthcare professionals.
BACKGROUND: Approximately one-fourth of patients with clinical stage I testicular cancer relapse. For decades, risk stratification has been based on different tumor characteristics for seminomas and non-seminomas. Previous studies primarily used Cox proportional-hazards models and included only a limited number of variables. Machine learning techniques can integrate large datasets and may uncover ...
OBJECTIVE: This study aimed to evaluate the coherence between data heterogeneity and model complexity by comparing seven convolutional neural network (CNN) architectures-trained with and without ImageNet pretraining-in a multiclass framework for the histopathological classification of three odontogenic tumors: adenomatoid odontogenic tumor, ameloblastoma, and ameloblastic carcinoma. The goal was t...
Laparoscopic cholecystectomy is the gold standard for treating symptomatic gallstones. Despite established safety strategies, variability in their ado...
Focal therapy offers a middle ground between active surveillance and whole-gland treatment for patients with low- and intermediate-risk prostate ...
Breast cancer (BC) represents the most common and one of the most lethal malignancies among women globally, ranking second only to lung cancer in term...
Esophageal squamous cell carcinoma (ESCC) lacks a standardized classification system, resulting in inconsistent clinical management and a suboptimal p...
BACKGROUND: Early and accurate classification of breast tumors from MRI scans is essential for improving patient outcomes. However, a key limitation o...
Hepatocellular carcinoma (HCC) is a leading cause of cancer-related mortality. It is often diagnosed at advanced stages and characterized by high recu...
Recent advances in three-dimensional single-cell-resolution imaging have begun to link organ-wide and cellular-level research in development and disea...
BACKGROUND: Cutaneous T-cell lymphomas (CTCLs) are a heterogeneous group of non-Hodgkin lymphomas, with mycosis fungoides (MF) being the most common t...
Follicles comprised of oocytes and surrounding cells are essential for reproductive function. They are fixed before birth and decrease thereafter thro...
Understanding electric-field-induced phase transitions is crucial for optimizing the ferroelectric and antiferroelectric properties of hafnium zirconi...
Radiation necrosis (RN) remains a challenging complication of upfront radiation therapy for both brain metastases and primary tumors. Despite developm...
Monoclonal gammopathies span a continuum from monoclonal gammopathy of undetermined significance (MGUS) and smoldering multiple myeloma (SMM) to overt...
PURPOSE: Differentiating conjunctival intraepithelial neoplasia (CIN) from pterygium and pseudopterygium remains clinically challenging, especially in...
OBJECTIVE: Aspartame, a widely used artificial sweetener, has attracted increasing attention for its potential systemic and oral toxicity. However, th...
Primary open-angle glaucoma (POAG) is one of the most common neurodegenerative diseases that cause irreversible optic nerve damage. POAG diagnosis req...
Quantitative susceptibility mapping (QSM) on MRI quantifies tissue magnetic susceptibility, which increases with iron accumulation, myelin loss, and n...
Cytopathology, often abbreviated as cytology, has a central role in the early detection of cancer, such as cervical, lung and bladder cancers, owing t...
BACKGROUND: Diabetic cardiomyopathy (DCM) is a major cardiovascular complication of diabetes mellitus, ultimately progressing to heart failure and inc...