Pathology

Latest AI and machine learning research in pathology for healthcare professionals.

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Artificial intelligence application in routine pathology: ChatGPT-4.0 and Gemini 2.5 pro performance in detection of MMR-deficiency in colorectal cancer.

PURPOSE: Immunohistochemistry (IHC) is a crucial step in the diagnostic and therapeutic management of colorectal carcinoma (CRC). This study aimed to explore the feasibility and diagnostic accuracy of general-purpose vision-language models (VLMs), specifically Gemini (2.5 Pro) and ChatGPT-4.0, for the automated classification of MMR status using immunohistochemical whole-slide images (WSIs). METHO...

Feb 17 2026 41722209

2D shape dataset of proximity-based spatial relation concepts.

Understanding how objects are positioned and related to each other in space is an important part of visual perception. Although people can recognize these relationships quite naturally, it is not easy to teach artificial intelligence to do the same. It becomes even more difficult when only a few examples are available for each type of spatial relation within a given domain. This dataset was create...

Feb 17 2026 41815797
Development and multicenter validation of a predictive model for malignant pleural effusion recurrence.

Early prediction of malignant pleural effusion (MPE) recurrence within 3 months is essential for optimizing management in lung cancer patients. This s...

Feb 17 2026 41847612
The feasibility and accuracy of real-time intra-operative confocal tissue diagnosis in brain and spine cancer surgery.

Real-time intra-operative brain tumour tissue analysis can reduce turnaround times and enable repeated sampling, enhancing diagnostic accuracy and gui...

Feb 17 2026 41699335
Analysing DCE-MRI scans using hybrid techniques for early detection of prostate cancer based on fusion features of handcrafted and deep learning features.

Prostate cancer is among the most diagnosed malignancies in men worldwide and a leading cause of cancer-related mortality. Early and accurate diagnosi...

Feb 17 2026 41700925
ERBB2 as a Prognostic Biomarker in Prostate Cancer: Integration of Single-Cell Transcriptomics, Deep Learning, and Immunohistochemical Validation.

Biochemical recurrence (BCR) is a critical factor affecting the prognosis of prostate cancer (PCa) patients, while T cell exhaustion and metastatic pr...

Feb 17 2026 41701406
Characterising processing conditions that artifactually bias human brain tissue transcriptomes.

Autopsy-derived brain tissue analysis is crucial for understanding neurobiology, but post-mortem handling can introduce artifacts. We studied adult hu...

Feb 17 2026 41702898
A Novel Approach to Ovarian Cancer Diagnosis via CT Imaging: GPT-4o-Driven Automated Feature Recognition and Validation in Clinical Settings.

BACKGROUND: Accurate non-invasive diagnosis of early-stage ovarian cancer remains challenging because of the limited number of biomarkers. Although ar...

Feb 17 2026 41703208
A Generative Foundation Model for Scalable Cytology Image Synthesis in AI-Powered Diagnostics.

PURPOSE: Cytology is a cornerstone of pathologic diagnosis. However, the use of artificial intelligence (AI) models for cytology-based diagnostics rem...

Feb 17 2026 41342884
Classification of small specimen uranium ores using LIBS combined with machine learning and deep learning algorithms.

In this study, classification models based on laser-induced breakdown spectroscopy (LIBS) technology, combined with machine learning (ML) and deep lea...

Feb 17 2026 41699974
AI-Enhanced Vibrational Capsule for Minimally Invasive Detection of Abnormal Bowel Tissue.

Colorectal cancer remains one of the leading causes of cancer mortality, and its prognosis is strongly dependent on early detection. Conventional diag...

Feb 17 2026 41700338
Bioelectronic interface for real-time brain biomarker analysis.

The brain is a highly complex organ, exhibiting a highly dynamic chemical environment, playing crucial role in coordinating pathophysiological process...

Feb 16 2026 41722490
YOLOv8 powered deep learning framework for detection and classification of oral potentially malignant disorders and oral cancer using intraoral images.

OBJECTIVE: This study aimed to develop deep learning framework based on the You Only Look Once version 8 (YOLOv8) instance segmentation architecture a...

Feb 16 2026 41826178
Analysis of passive bloodstain morphology across surface textures and drop heights using deep learning.

Bloodstain pattern analysis (BPA) is a critical forensic science tool for reconstructing crime scene events. In this study, the effect of substrate ty...

Feb 16 2026 41707408
Incorporating global-local tissue changes to predict future breast cancer from longitudinal screening mammograms.

Early detection of breast cancer (BC) through mammography screening is critical for reducing mortality and improving patient outcomes. However, full-p...

Feb 16 2026 41747525
Identification of pyroptosis-associated genes for the prediction of metabolic dysfunction-associated steatohepatitis based on interpretable machine learning models.

BACKGROUND: Pyroptosis, a pro-inflammatory form of regulated cell death mediated by gasdermin pore formation and typically triggered by inflammasome a...

Feb 16 2026 41722245
Artificial intelligence-based classification of Spitz tumors.

Spitz tumors are diagnostically challenging due to overlap in atypical histological features with conventional melanomas. We investigated to what exte...

Feb 16 2026 41847156
Computer Vision for Preoperative Soft-Tissue Landmarking in Cleft Lip Repair: A Systematic Review.

BACKGROUND: Cleft lip repair presents complex surgical challenges requiring precise preoperative planning. Emerging computer vision technologies power...

Feb 16 2026 41701135
Recent Advances in Cancer Diagnostics: Exotic Animal Medicine and Beyond.

Recent advances in veterinary diagnostic oncology have significantly improved neoplasia detection in animals, including zoo, exotic, and wildlife spec...

Feb 16 2026 41702787
Harnessing artificial intelligence in gastrointestinal endoscopy for early detection of dysplastic lesions in inflammatory bowel disease.

Artificial intelligence (AI) has become an increasingly valuable tool in gastrointestinal endoscopy, especially in the context of inflammatory bowel d...

Feb 16 2026 41700159
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