Pathology

Latest AI and machine learning research in pathology for healthcare professionals.

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CvTFuse: An unsupervised medical image fusion method of gliomas T1-DWI mode.

BACKGROUND: DWI can provide microscopic information on the diffusion of water molecules, whereas T1WI can provide high-resolution anatomical and histological information. PURPOSE: Accurately and effectively fusing different MRI modalities can precisely localize lesion areas and provide rich information for analyzing the nature of lesions. METHODS: We propose a dual-branch medical image fusion netw...

Jan 15 2026 41547498

A systematic review of artificial intelligence models in ocular tumour diagnosis.

INTRODUCTION: Ocular tumours are detrimental to the quality of life and survival. The diagnostic capabilities of artificial intelligence (AI) have increased in the past decade. This systematic review aims to evaluate the diagnostic performance of AI models across external, anterior segment, and posterior segment ocular tumours. METHODS: A systematic literature search of Ovid Embase, MEDLINE, and t...

Jan 15 2026 41548879
Identification of COL8A2, MICAL2, and TNFSF10 as potential biomarkers associated with both exercise response and osteoarthritis: a multi-omics integration study.

UNLABELLED: To identify molecular biomarkers associated with both osteoarthritis (OA) pathology and exercise response through multi-omics integration....

Jan 14 2026 41550487
Sex and Stress Govern the Function and Innervation of a Basolateral Amygdala to Nucleus Accumbens Corticotropin-Releasing Hormone/GABA-Expressing Projection.

Motivated behaviors are executed by refined brain circuits. Early-life adversity (ELA) is a risk for human affective disorders involving dysregulated ...

Jan 14 2026 41271439
Comprehensive review on immunotherapy for hepatocellular carcinoma: Current status and future perspectives.

Hepatocellular carcinoma (HCC), the most common form of primary liver cancer, remains a major global health concern due to its high incidence and mort...

Jan 14 2026 41532498
Approaches to assessing completeness of polyp resections in clinical practice: a systematic scoping review.

BACKGROUND: Protocols for standardized assessment of complete colorectal polyp resection are lacking. This may contribute to divergent quality standar...

Jan 14 2026 41534867
Multicenter evaluation of interpretable AI for coronary artery disease diagnosis from PET biomarkers.

Positron emission tomography (PET)/computed tomography (CT) for myocardial perfusion imaging (MPI) provides multiple imaging biomarkers, often evaluat...

Jan 14 2026 41535345
Identification and validation of a refined CAF-Associated diagnostic signature in breast cancer.

Breast cancer remains a major global health challenge with high incidence and mortality rates among women. Recent studies have highlighted the critica...

Jan 14 2026 41535351
A multi-modal approach for decision making in bladder cancer.

Bladder cancer remains a major global health challenge, characterized by diagnostic uncertainty, substantial treatment costs and high recurrence rates...

Jan 14 2026 41535603
Chronic stress raises baseline circulating corticosterone and reduces vocal plasticity in male budgerigars, an avian model for adult vocal learning.

Chronic stress affects cognitive function across many domains, including memory, decision making and learning. While the effects of early-life stress ...

Jan 14 2026 41538908
Cutting-Edge AI Technologies in Skin Cancer Applications.

The rapid development of multimodal large language models (LLMs) such as GPT and Med-PaLM is reshaping medical practice. Skin cancer, one of the most ...

Jan 14 2026 41544780
Spectral attribute reasoning for interpretable multi-modal pathological segmentation.

Accurate segmentation of diverse histological entities is fundamental in computational pathology and critical for clinical diagnosis. Advances in micr...

Jan 14 2026 41547006
Artificial intelligence in metabolic dysfunction-associated steatotic liver disease: Transforming diagnosis and therapeutic approaches.

Metabolic dysfunction-associated steatotic liver disease (MASLD) is an increasingly prevalent condition associated with hepatic complications and card...

Jan 14 2026 41551828
Deep learning feature-based model on abdominal radiography outperforms experts for early necrotizing enterocolitis diagnosis in neonates.

OBJECTIVES: Plain abdominal radiography is a widely used imaging modality for diagnosing neonatal necrotizing enterocolitis (NEC), but the characteris...

Jan 13 2026 41528473
Automated high-throughput microscopy screening unveiled new Listeria monocytogenes genes involved in cell infection.

To uncover novel genetic factors required for Listeria monocytogenes cell infection, we developed an automated high-throughput microscopy screening pi...

Jan 13 2026 41548381
Assessment of Generative AI Chatbots for Neonatal Diagnostic Reasoning: A Comparative Concordance and Diagnosis Acceptability Analysis.

OBJECTIVES: To assess the concordance and diagnosis acceptability of differential diagnoses (DDs) generated by artificial intelligence (AI) chatbots c...

Jan 13 2026 41528602
Neural networks for faster laser ultrasound tomography in tissue phantoms.

Speed of sound (SoS) mapping provides quantitative and localised information about a material's acoustic properties, allowing identification of spatia...

Jan 13 2026 41716222
NEIL1 suppresses ROS accumulation to promote temozolomide resistance and malignant progression in glioma cells.

BACKGROUND: Glioma is the most common malignant primary brain tumor. Temozolomide (TMZ) is the standard first-line chemotherapy, but its efficacy is s...

Jan 13 2026 41534309
Cell type composition in bulk prostate cancer tissue is a prognostic biomarker.

Prostate cancer, among the most prevalent cancer types globally, exhibits marked heterogeneity and varying disease progression and clinical outcomes. ...

Jan 13 2026 41534468
Diagnostic Accuracy of Histopathologic Features Suggestive of Dermatophytosis: A Retrospective Cohort Selection Study With Machine Learning Evaluation.

BACKGROUND: Histopathologic features have been proposed as clues to potential dermatophyte infection. The inter-observer reproducibility and diagnosti...

Jan 12 2026 41527154
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