Pathology

Latest AI and machine learning research in pathology for healthcare professionals.

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Early breast cancer detection via infrared thermography using a CNN enhanced with particle swarm optimization.

Breast cancer remains the most prevalent cause of cancer-related mortality among women worldwide, with an estimated incidence exceeding 500,000 new cases annually. Timely diagnosis is vital for enhancing therapeutic outcomes and increasing survival probabilities. Although conventional diagnostic tools such as mammography are widely used and generally effective, they are often invasive, costly, and...

Jul 13 2025 40652141

Large language models in medical education: a comparative cross-platform evaluation in answering histological questions.

Large language models (LLMs) have shown promising capabilities across medical disciplines, yet their performance in basic medical sciences remains incompletely characterized. Medical histology, requiring factual knowledge and interpretative skills, provides a unique domain for evaluating AI capabilities in medical education. To evaluate and compare the performance of five current LLMs: GPT-4.1, Cl...

Jul 12 2025 40651009
Accurate and real-time brain tumour detection and classification using optimized YOLOv5 architecture.

The brain tumours originate in the brain or its surrounding structures, such as the pituitary and pineal glands, and can be benign or malignant. While...

Jul 12 2025 40651993
Development and validation of a prognostic model for predicting survival and immunotherapy benefits in melanoma based on metabolism-relevant genes.

Skin cutaneous melanoma (SKCM) is a fatal form of skin cancer. Metabolism-related genes (MRGs) comprise a group of genes that possess the ability to m...

Jul 12 2025 40652057
Establishing an AI-based diagnostic framework for pulmonary nodules in computed tomography.

BACKGROUND: Pulmonary nodules seen by computed tomography (CT) can be benign or malignant, and early detection is important for optimal management. Th...

Jul 12 2025 40652218
Screening and investigating the regulatory mechanisms of oxidative stress-related biomarkers in thoracic aortic aneurysms.

Excess reactive oxygen species leading to oxidative stress has been identified as a significant factor in cardiovascular disease. However, the molecul...

Jul 11 2025 40643772
Size-Specific Predictors for Malignancy Risk in Follicular Thyroid Neoplasms: Machine Learning Analysis.

BACKGROUND: Surgeons often face challenges in distinguishing between benign and malignant follicular thyroid neoplasms (FTNs), particularly small tumo...

Jul 11 2025 40644624
Machine learning-assisted assessment of extracellular vesicles can monitor cellular rejection after heart transplant.

BACKGROUND: Heart transplant rejection, particularly acute cellular rejection (ACR), remains a critical post-operative concern, despite declining inci...

Jul 11 2025 40640467
SPP1 promotes malignant characteristics and drug resistance in hepatocellular carcinoma by activating fatty acid metabolic pathway.

Hepatocellular carcinoma (HCC) progression and prognosis are influenced by various molecular markers. This study aimed to identify the hub gene associ...

Jul 11 2025 40640504
Three-dimensional digital quantitative analysis of periodontal and peri-implant phenotype-A narrative review.

3D digital evaluation of the periodontal and peri-implant tissue, including CBCT, intraoral scanning, optical surface scanning, and ultrasonography, i...

Jul 11 2025 40641458
Decoding tissue complexity: multiscale mapping of chemistry-structure-function relationships through advanced visualization technologies.

Comprehensively acquiring biological tissue information is pivotal for advancing our understanding of biological systems, elucidating disease mechanis...

Jul 10 2025 40476698
Deformable detection transformers for domain adaptable ultrasound localization microscopy with robustness to point spread function variations.

Super-resolution imaging has emerged as a rapidly advancing field in diagnostic ultrasound. Ultrasound Localization Microscopy (ULM) achieves sub-wave...

Jul 10 2025 40640235
Comprehensive multi-omics and machine learning framework for glioma subtyping and precision therapeutics.

Glioma is a highly heterogeneous and aggressive brain tumour that demands an integrated understanding of its molecular and immunological landscape. We...

Jul 10 2025 40640380
Deep learning on routine full-breast mammograms enhances lymph node metastasis prediction in early breast cancer.

With the shift toward de-escalating surgery in breast cancer, prediction models incorporating imaging can reassess the need for surgical axillary stag...

Jul 10 2025 40640522
Recent advancement in endoscopic diagnosis for risk stratification of gastric cancer.

Approximately 90% of cases of gastric cancer (GC) are caused by Helicobacter pylori infection, and screening esophagogastroduodenoscopy is effective f...

Jul 10 2025 40633804
TRIM29 alleviates intervertebral disc degeneration through the PI3K/AKT/mTOR pathway.

Intervertebral disc degeneration (IDD), a prevalent spinal condition linked to low back pain, has substantial genetic components, necessitating deeper...

Jul 10 2025 40634479
An overview of reliable and representative DVC measurements for musculoskeletal tissues.

Musculoskeletal tissues present complex hierarchical structures and mechanical heterogeneity across multiple length scales, making them difficult to c...

Jul 10 2025 40636996
Nondisruptive inducible labeling of ER-membrane contact sites using the Lamin B receptor.

Membrane contact sites (MCSs) are areas of close proximity between organelles that allow the exchange of material, among other roles. The endoplasmic ...

Jul 10 2025 40638559
Mitosis detection in histopathological images using customized deep learning and hybrid optimization algorithms.

Identifying mitosis is crucial for cancer diagnosis, but accurate detection remains difficult because of class imbalance and complex morphological var...

Jul 10 2025 40638590
Nuclei segmentation and classification from histopathology images using federated learning for end-edge platform.

Accurate nuclei segmentation and classification in histology images are critical for cancer detection but remain challenging due to color inconsistenc...

Jul 10 2025 40638627
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