Pathology

Latest AI and machine learning research in pathology for healthcare professionals.

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Microplastic incorporation into soil aggregates of arable land.

Agricultural mulch films are widely applied to increase crop productivity but are a significant source of microplastics (MPs) in the environment. We investigated the incorporation of conventional and biodegradable MPs into soil aggregates from agricultural fields in Finland, Germany and Spain, hypothesising that (i) MPs become increasingly occluded within soil aggregates over time, (ii) the extent...

Aug 2 2026 42551369

Precision Endodontics-Advancing Towards Omics-Guided Personalisation: A Narrative Review.

AIM: To critically evaluate the emerging contribution of genomics, transcriptomics, proteomics, metabolomics and microbiomics to the development of precision endodontics, and to examine the opportunities and translational challenges associated with integrating omics technologies into clinical endodontic practice. METHODOLOGY: This narrative review synthesises recent literature across the biomedica...

Aug 2 2026 42543866
Exploratory machine learning-based early post-treatment assessment of willingness to reuse rubber dam isolation after microscopic root canal treatment.

ObjectiveTo explore factors associated with willingness to reuse rubber dam isolation after microscopic root canal treatment and develop an explorator...

Aug 1 2026 42541412
A Dynamic Prognostic and Adaptive Treatment Framework for Advanced Biliary Tract Cancer.

BACKGROUND & AIMS: First-line immuno-chemotherapy is standard for advanced biliary tract cancer (BTC), but outcomes vary substantially, necessitating ...

Aug 1 2026 42542210
Subphenotypes of pneumonia defined by pulmonary histopathological features.

RATIONALE: Establishing subphenotypes of pneumonia based on host biology will be a step toward using host-directed therapies (to complement microbe-di...

Aug 1 2026 42089675
Impact of neoadjuvant chemotherapy on breast tissue density and its correlation with pathologic response: a retrospective artificial intelligence-enhanced radiological study.

OBJECTIVES: This study evaluates the impact of neoadjuvant chemotherapy (NAT) on breast tissue density and examines the correlation between density ch...

Aug 1 2026 42179163
Molecular Characterization and Immune Modulation of Schwann Cells in Vestibular Schwannoma.

Vestibular schwannoma (VS) is a benign tumor originating from the vestibular nerve, and its complex tumor microenvironment presents significant challe...

Aug 1 2026 42226390
Adaptive Admittance Control for Robotic Ultrasound Examination Based on a Breast Biomechanical Model.

BACKGROUND: Autonomous Robotic Ultrasound Systems (ARUS) enable standardized breast cancer screening, but accurate breast localization and the nonline...

Aug 1 2026 42379153
In Vivo Assessment of Placental Structure and Perfusion in Late-Gestation Pregnancies and Their Association With Fetal Growth.

Adequate placental structure and function are crucial for fetal growth, while placental dysfunction often leads to fetal growth restriction (FGR), ass...

Aug 1 2026 42387322
Automated Differentiation of Oral Red-White Lesions: An Interpretable Deep Learning Approach Combining Ensemble Architectures and Saliency Maps.

INTRODUCTION: Oral Potentially Malignant Disorders (OPMDs), including Leukoplakia and Erythroplakia, carry significant risks of malignant transformati...

Aug 1 2026 42478563
Applications of Artificial Intelligence in Cancer Diagnosis and Treatment.

Driven by changes in lifestyle and environmental factors, the global incidence of cancer is steadily increasing, which has established it as a leading...

Aug 1 2026 42504045
Screening efficiency over experience: Rapid target detection in low-power field as a modifiable cognitive biomarker for diagnostic accuracy in digital cytology.

BACKGROUND: Traditionally, cytology expertise has been equated with professional experience. However, the transition to whole-slide imaging and artifi...

Aug 1 2026 42516004
Pitfalls and Emerging Trends in AI-driven Pathological Analysis of Metastatic Brain Tumors.

The integration of artificial intelligence (AI) and computational pathology has the potential to refine prognostic stratification in patients with met...

Aug 1 2026 42527096
Keratan Sulfate: An Electroconductive Glycosaminoglycan at the Interface of Sensory Perception and Neural Signaling.

This narrative review highlights the functional attributes of keratan sulfate (KS), a glycosaminoglycan integral to structural support, hydration, and...

Aug 1 2026 42535754
CHAF1A identified as a candidate biomarker and potential therapeutic target in Burkitt lymphoma through integrated bioinformatics and histopathological analysis.

BACKGROUND: Burkitt lymphoma (BL) is a highly aggressive malignancy with limited effective treatments due to toxicity/resistance. Identifying and prio...

Jul 31 2026 42535765
Machine learning-based molecular detection using dark-field observation of two different nanoparticles.

Metal nanoparticles, such as gold nanoparticles (AuNPs), are widely used as biosensing materials. In previous studies, dark-field microscopy (DFM) has...

Jul 31 2026 42540679
Advances in peptide applications for hard tissue repair and regeneration: multidisciplinary perspectives.

The rising prevalence of bone and dental diseases, compounded by an ageing population, underscores the urgent need for advanced materials in hard tiss...

Jul 31 2026 42535931
Toward a Structured Imaging Reporting System for Kidney Masses: The Molecular Imaging Perspective on KI-RADS.

Recently, a structured approach to renal mass characterization known as the Kidney Imaging Reporting and Data System (KI-RADS) was proposed. In that p...

Jul 31 2026 42536267
Multimodal Management of Pain in Oral Squamous Cell Carcinoma: A Mechanism-Based Approach.

PURPOSE OF REVIEW: Oral squamous cell carcinoma (OSCC) is frequently associated with severe nociceptive and neuropathic pain that adversely affects pa...

Jul 31 2026 42536272
Radiomics and machine learning analysis of ultrasound images in Bethesda IV thyroid nodules: a retrospective monocentric study.

Bethesda IV thyroid nodules remain a major diagnostic challenge because cytology cannot reliably distinguish benign from malignant follicular-patterne...

Jul 31 2026 42536308
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