Latest AI and machine learning research in pathology for healthcare professionals.
Breast cancer (BC) is a highly complex and heterogeneous malignancy and the most prevalent cancer among women worldwide. The diagnosis, prognosis, and the treatment of BC pose significant challenges that are responsible for their limited therapeutic efficacy. Omics-based technologies have gained substantial attention in BC diagnosis through molecular profiling and diverse clinical analytics. The i...
Bisphenol A (BPA) is a ubiquitous environmental pollutant, but its relationship with chronic obstructive pulmonary disease (COPD) and the underlying toxicological mechanisms remain unclear. To address this, we employed an integrative multi-omics strategy that included cross-sectional analysis of the National Health and Nutrition Examination Survey (NHANES) data, Mendelian randomization, network to...
BACKGROUND: Hyperuricemia (HUA) is a major risk factor for gout and multiple metabolic disorders. Although serum uric acid (UA) is the gold standard f...
BACKGROUND: Anastomotic leakage remains a critical complication following esophagectomy, occurring in 8-20% of patients. While indocyanine green fluor...
INTRODUCTION: Thyroid cancer is the most common endocrine malignancy, and despite advances in understanding its genomic drivers, significant challenge...
Liquid biopsy holds immense potential for the early detection of cancer, yet its clinical utility is hindered not by the lack of available tumor-assoc...
BACKGROUND: Accurate preoperative distinction between uterine leiomyoma (UM) and uterine leiomyosarcoma (UMS) remains a major clinical challenge. Misc...
BACKGROUND/AIMS: Risk prediction models (RPMs) based on histopathological analysis of oral epithelial dysplasia (OED) are increasingly used to stratif...
Genetic variation influences human physiology across biological scales from molecules to cells, tissues, organs and the whole organism. Unravelling ho...
This review highlights that integrating physiological, molecular, imaging, and AI-based approaches enables early and reliable detection of graft incom...
Ultrasound elastography measures tissue stiffness and has demonstrated clinical utility across multiple medical specialties. In respiratory medicine, ...
Current platforms for drug screening typically do not account for the tumor microenvironment. Microfluidic shear flow assays provide a highly sensitiv...
INTRODUCTION: Biliary tract cancer (BTC) is a biologically heterogeneous and highly aggressive malignancy with limited therapeutic options and poor su...
The adoption of whole-slide imaging is establishing a new paradigm in digital pathology. However, the translation of artificial intelligence (AI) from...
PURPOSE OF REVIEW: Heart failure (HF) is increasingly understood not as a single, uniformly treated diagnosis but as a heterogeneous syndrome requirin...
Deep neural networks (DNNs) are vulnerable to backdoor attacks, where the backdoored models behave normally on benign samples but misclassify trigger-...
BACKGROUND: Centrosome-related genes (CRGs) regulate cell division and genomic stability and may influence tumor progression, but their prognostic and...
Single-molecule orientation localization microscopy (SMOLM) is an optical means to measure complex transport in charged and crowded conditions, such a...
BACKGROUND: PCLAF (PCNA clamp-associated factor) is a protein involved in DNA replication and DNA repair. Aberrant PCLAF expression has been reported ...
OBJECTIVE: Ultrasound-guided needle placement has been commonly used for minimally invasive clinical procedures, including biopsy, regional anesthesia...