Pathology

Latest AI and machine learning research in pathology for healthcare professionals.

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The effect of incorporating domain knowledge with deep learning in identifying benign and malignant gastric whitish lesions: A retrospective study.

BACKGROUND AND AIM: Early whitish gastric neoplasms can be easily misdiagnosed; differential diagnosis of gastric whitish lesions remains a challenge. We aim to build a deep learning (DL) model to diagnose whitish gastric neoplasms and explore the effect of adding domain knowledge in model construction.

Feb 27 2024 38414305

Automated AI-based grading of neuroendocrine tumors using Ki-67 proliferation index: comparative evaluation and performance analysis.

Early detection is critical for successfully diagnosing cancer, and timely analysis of diagnostic tests is increasingly important. In the context of neuroendocrine tumors, the Ki-67 proliferation index serves as a fundamental biomarker, aiding pathologists in grading and diagnosing these tumors based on histopathological images. The appropriate treatment plan for the patient is determined based on...

Feb 27 2024 38409645
Deep-learning image analysis for high-throughput screening of opsono-phagocytosis-promoting monoclonal antibodies against Neisseria gonorrhoeae.

Antimicrobial resistance (AMR) is nowadays a global health concern as bacterial pathogens are increasingly developing resistance to antibiotics. Monoc...

Feb 27 2024 38413727
Comparison of machine learning-based CT fractional flow reserve with cardiac MR perfusion mapping for ischemia diagnosis in stable coronary artery disease.

OBJECTIVES: To compare the diagnostic performance of machine learning (ML)-based computed tomography-derived fractional flow reserve (CT-FFR) and card...

Feb 26 2024 38409549
OralEpitheliumDB: A Dataset for Oral Epithelial Dysplasia Image Segmentation and Classification.

Early diagnosis of potentially malignant disorders, such as oral epithelial dysplasia, is the most reliable way to prevent oral cancer. Computational ...

Feb 26 2024 38409608
Research Progress of Artificial Intelligence in the Grading and Classification of Meningiomas.

A meningioma is a common primary central nervous system tumor. The histological features of meningiomas vary significantly depending on the grade and ...

Feb 26 2024 38413314
Recommendations for using artificial intelligence in clinical flow cytometry.

Flow cytometry is a key clinical tool in the diagnosis of many hematologic malignancies and traditionally requires close inspection of digital data by...

Feb 26 2024 38407537
Automated curation of large-scale cancer histopathology image datasets using deep learning.

BACKGROUND: Artificial intelligence (AI) has numerous applications in pathology, supporting diagnosis and prognostication in cancer. However, most AI ...

Feb 26 2024 38409878
A deep learning based holistic diagnosis system for immunohistochemistry interpretation and molecular subtyping.

BACKGROUND: Breast cancer in different molecular subtypes, which is determined by the overexpression rates of human epidermal growth factor receptor 2...

Feb 26 2024 38412576
A Machine Learning-Driven Comparison of Ion Images Obtained by MALDI and MALDI-2 Mass Spectrometry Imaging.

Matrix-assisted laser desorption ionization mass spectrometry imaging (MALDI-MSI) enables label-free imaging of biomolecules in biological tissues. Ho...

Feb 26 2024 38407924
Modeling 5-FU-Induced Chemotherapy Selection of a Drug-Resistant Cancer Stem Cell Subpopulation.

(1) Background: Cancer stem cells (CSCs) are a subpopulation of cells in a tumor that can self-regenerate and produce different types of cells with th...

Feb 25 2024 38534924
Deep Learning for Perfusion Cerebral Blood Flow (CBF) and Volume (CBV) Predictions and Diagnostics.

Dynamic susceptibility contrast magnetic resonance perfusion (DSC-MRP) is a non-invasive imaging technique for hemodynamic measurements. Various perfu...

Feb 24 2024 38402314
Deep neural networks can differentiate thyroid pathologies on infrared hyperspectral images.

BACKGROUND AND OBJECTIVE: The thyroid is a gland responsible for producing important body hormones. Several pathologies can affect this gland, such as...

Feb 24 2024 38442622
Artificial intelligence support in MR imaging of incidental renal masses: an early health technology assessment.

OBJECTIVE: This study analyzes the potential cost-effectiveness of integrating an artificial intelligence (AI)-assisted system into the differentiatio...

Feb 23 2024 38388721
Translating the regulatory landscape of medical devices to create fit-for-purpose artificial intelligence (AI) cytometry solutions.

The implementation of medical software and artificial intelligence (AI) algorithms into routine clinical cytometry diagnostic practice requires a thor...

Feb 23 2024 38396223
ECG-only explainable deep learning algorithm predicts the risk for malignant ventricular arrhythmia in phospholamban cardiomyopathy.

BACKGROUND: Phospholamban (PLN) p.(Arg14del) variant carriers are at risk for development of malignant ventricular arrhythmia (MVA). Accurate risk str...

Feb 23 2024 38403235
Quantitative assessment of H&E staining for pathology: development and clinical evaluation of a novel system.

BACKGROUND: Staining tissue samples to visualise cellular detail and tissue structure is at the core of pathology diagnosis, but variations in stainin...

Feb 23 2024 38395890
A deep learning dataset for sample preparation artefacts detection in multispectral high-content microscopy.

High-content image-based screening is widely used in Drug Discovery and Systems Biology. However, sample preparation artefacts may significantly deter...

Feb 23 2024 38395957
Virtual histological staining of unlabeled autopsy tissue.

Traditional histochemical staining of post-mortem samples often confronts inferior staining quality due to autolysis caused by delayed fixation of cad...

Feb 23 2024 38396004
Validation of artificial intelligence-based digital microscopy for automated detection of Schistosoma haematobium eggs in urine in Gabon.

INTRODUCTION: Schistosomiasis is a significant public health concern, especially in Sub-Saharan Africa. Conventional microscopy is the standard diagno...

Feb 23 2024 38394298
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