Pathology

Artificial intelligence-assisted FTIR spectroscopy for hormone receptor subtyping in formalin-fixed breast Cancer tissues.

BACKGROUND: Determination of estrogen receptor (ER) and progesterone receptor (PR) status is critica...

GHMS-CycleGAN: Graph-Based Hierarchical Multi-stain CycleGAN for Stain Normalization and Classification in Digital Pathology.

The emergence of digital pathology (DP) has provided numerous computer-aided diagnosis (CAD) opportu...

Physics-based simulation of ultrasound propagation from MRI volumes for cross-modal breast imaging.

BACKGROUND: Magnetic resonance imaging (MRI) of breast tissue is often used to definitively diagnose...

Molecularly Engineered SERS Platform with Microturbulence-Enhanced Electrohydrodynamics for Multiplexed Profiling of Lung Cancer ctDNA.

Precise profiling of multiple circulating tumor DNA (ctDNA) is hindered by the challenge of resolvin...

Technical Description of the Mini Far-Lateral Approach: A Refined, Stability-Preserving Corridor to the Petroclival Region.

BACKGROUND AND OBJECTIVES: The far-lateral approach remains essential for accessing ventral and vent...

Enhancing drug synergy in malignant diseases with deep architecture optimization algorithms.

Malignant diseases remain one of the leading causes of death globally. Drug synergy has emerged as a...

Artificial Intelligence and Nasal Cytology: Toward a Comprehensive Cytological Endotyping of Rhinitis.

Comparison of breast ultrasound image classification accuracy between convolutional neural networks and human experts using multicenter external validation cohort data.

PURPOSE: In recent years, much research has been conducted on ultrasound diagnosis of breast tumors ...

Contemporary Indications and Technical Limits of Transoral Laser Microsurgery for Laryngeal Squamous Cell Carcinoma.

Transoral laser microsurgery (TOLMS) is an established organ-preserving treatment for early-stage an...

A Deep Learning-Driven Framework Integrating Organoid-Based Functional Validation Identifies Universal Neoantigens from Recurrent Glioma Mutations.

Glioblastoma (GBM) is the most common malignant intracranial tumor in adults, with a median survival...

Prostate cancer tissue mapping and stratification using DRAQ5 and Eosin fluorescent labels integrated with AI classification and segmentation algorithms.

BACKGROUND: Fluorescent microscopy using the DRAQ5 and Eosin probes has been shown in the literature...

Unlocking azobenzene isomerization mechanisms via an LLM agent-driven workflow integrating simulation, experiment, and machine learning.

Bridged azobenzene derivatives are key photo-responsive molecular switches. However, probing and int...

Human microphysiological systems of aging recreate the in vivo process expediting evaluation of anti-geronic strategies.

The search for biological mechanisms of human aging is stalled by a lack of suitable models, and it ...

Advanced imaging techniques for tumor intraoperative navigation imaging.

Cancer remains a leading cause of mortality and morbidity, with surgical resection being a fundament...

Finding the most promising indications for novel treatments in oncology.

Tackling cancer with effective therapies is a major challenge our society faces with significant cos...

AI-Assisted Tissue Classification in Chironomus riparius: A Potential Tool for Ecotoxicological Studies.

Histological techniques are valuable tools in various biological and medical disciplines. They have ...

A Multimodal Attention Fusion-Based Model for Pathological Voice Detection.

Pathological voice detection provides a non-invasive and cost-effective approach for the early scree...

Efficient machine learning models leveraging DCE‑MRI morphological and dynamic features allow accurate breast lesion classification.

We propose an ensemble learning approach to classify malignant versus benign breast lesions leveragi...

[Comprehensive diagnosis and treatment of distal biliary strictures: multidisciplinary collaboration and precision surgical strategies].

Distal biliary strictures (DBS) are a common and complex clinical problem in pancreaticobiliary dise...

Artificial intelligence for detection, grading, and prognostication in prostate cancer pathology: A scoping review.

Artificial intelligence (AI) has been transforming many aspects of medical care. In prostate cancer,...

International Delphi consensus on acute kidney injury: Foundations for AI-driven digital twin development in critical care nephrology.

BACKGROUND: Acute kidney injury (AKI) in critically ill patients is clinically complex and heterogen...