Latest AI and machine learning research in pathology for healthcare professionals.
The accurate categorisation of histopathological images is crucial for the reliable identification of morphologically similar cancers, including lung and colon cancer. According to the WHO and IARC, lung cancer accounted for approximately 2.48 million new cases and 1.8 million deaths worldwide in 2022, making it the leading cause of cancer-related mortality worldwide. Colorectal cancer also repres...
BACKGROUND: First-line treatment of gastric cancer is evolving with the integration of immune checkpoint inhibitors (ICIs) and targeted agents, complicating biomarker stratification. Claudin 18.2 (CLDN18.2) is an established target for zolbetuximab; however, immunohistochemistry (IHC) is limited by tissue requirements, cost, and turnaround time. Artificial intelligence (AI) analysis of hematoxylin...
BACKGROUND: KRAS-mutant lung adenocarcinoma (LUAD) is associated with aggressive phenotypes and therapy resistance, which highlights an urgent need to...
Among various types of cancers, lung cancer causes the highest mortality globally, necessitating prompt diagnosis for effective treatment. Traditional...
Image-level classification of oral-cavity photographs remains challenging because oral-cancer appearances are heterogeneous and many public datasets l...
This study aimed to evaluate the feasibility of a cone-beam computed tomography (CBCT)-based deep learning (DL) model for predicting three-dimensional...
BACKGROUND: Timely diagnosis and treatment of fibrotic interstitial lung disease (ILD) is crucial to preserve lung function and limit healthcare costs...
Spatial transcriptomics enables the systematic exploration of how gene expression patterns are organized within intact tissues, yet effective analysis...
PURPOSE: To evaluate the diagnostic value of machine learning models based on dual-phase 99mTc-MIBI SPECT/CT semiquantitative parameters for different...
Human epidermal growth factor receptor 2 (HER2)-targeted therapies have revolutionized breast cancer treatment, necessitating standardized HER2 testin...
The efficient capture and sensitive detection of exosomes from complex biological samples remain critical challenges for liquid biopsy-based cancer di...
BACKGROUND: Accurate prediction of breast cancer biomarkers - including oestrogen receptor (ER), progesterone receptor (PR), human epidermal growth fa...
Active surveillance (AS) is widely used for men with low-risk and selected favorable intermediate-risk prostate cancer, but pathways remain heterogene...
BACKGROUND: Diffuse gliomas remain among the most surgically challenging tumors, characterized by their infiltrative nature, proximity to eloquent bra...
Two-dimensional (2D) materials exhibit a wide range of electronic properties that make them promising candidates for next-generation nanoelectronic de...
Pulmonary tumor diagnosis with ultrasound is clinically valuable yet technically challenging. Although deep learning has shown promise in supporting s...
Hospital-acquired infections (HAIs) remain a major global concern, contributing significantly to increased morbidity, mortality, and healthcare costs....
BACKGROUND: Reproducibility and cross-species translation using the domestic pig (Sus scrofa) are limited by the lack of a standardised molecular fram...
Hepatocellular carcinoma (HCC) related to hepatitis B virus (HBV) infection predominantly affects males, yet few studies have investigated the associa...
Cervical cancer is one of the most common malignant tumors of the female reproductive tract, ranking fourth among all female malignancies. Currently, ...