Pathology

Latest AI and machine learning research in pathology for healthcare professionals.

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Accuracy of Automated Deep Learning versus Expert Clinicians for Diagnosis of Acute Lacunar Stroke on CT Perfusion.

BACKGROUND: Accurate diagnosis of lacunar stroke in the acute setting is challenging and often depends on MRI or clinical suspicion. CT perfusion (CTP) has only modest diagnostic accuracy and substantial interobserver variability yet is widely available. Artificial intelligence (AI) based tools may therefore be a valuable decision-support aid to improve the reliability of CTP interpretation. MATER...

Jun 2 2026 42229993

Multimodal Ultrasound Integration Pathways and Paradigm Innovations in Precision Diagnosis and Treatment of Thyroid Cancer.

RATIONALE AND OBJECTIVES: Thyroid cancer, the fastest-growing endocrine malignancy, is shifting from morphological evaluation to molecular-functional imaging. This review systematically evaluates the translational value of multimodal ultrasound technologies-high-frequency ultrasound (HFUS), elastography, contrast-enhanced ultrasound (CEUS), and super-resolution imaging (SRI)-across the entire "scr...

Jun 2 2026 42230172
Compilation of Creep Property Data for Nuclear Structural Materials.

As advanced nuclear reactor designs move towards higher operating temperatures, rapid nuclear material creep research has become increasingly importan...

Jun 2 2026 42230675
Deep learning prediction of pathological complete response in breast cancer using Mamba architecture.

Deep learning is capable of efficiently predicting the therapeutic efficacy of neoadjuvant chemotherapy (NAC) in breast cancer. However, current metho...

Jun 2 2026 42230774
Integrating network toxicology, machine learning, and single-cell sequencing to reveal the FASN-mediated role of phenolic endocrine disruptors in water in promoting prostate cancer.

BACKGROUND: Phenolic endocrine-disrupting chemicals (EDCs) like nonylphenol (NP) and octylphenol (OP) are widespread water pollutants. Their estrogen-...

Jun 2 2026 42228706
Landscape of T-cell bispecific antibodies in cancer therapy: therapeutic strategies, challenges and future prospection.

T-cell bispecific antibodies (TCBs), a specialized subclass of bispecific antibodies (BsAbs), are engineered to simultaneously engage T cells and tumo...

Jun 1 2026 42226254
Deep learning-driven decoding of ubiquitination: from regulatory mechanisms to targeted protein degradation.

BACKGROUND: Ubiquitination is a highly dynamic post-translational modification that plays central roles in protein homeostasis, signal transduction, i...

Jun 1 2026 42226266
Development and validation of a machine learning model for predicting distant metastasis in patients with renal cell carcinoma: a population-based study.

BACKGROUND: Distant metastasis is the leading cause of death in renal cell carcinoma (RCC), yet accurate prediction tools remain lacking. We aimed to ...

Jun 1 2026 42226290
Integration of Raman Spectroscopy and Metabolomics for Early Breast Cancer Detection and Classification.

Breast cancer, now the fourth leading cause of cancer-related mortality worldwide, necessitates early detection for improved clinical outcomes. Conven...

Jun 1 2026 42226429
Machine learning in tissue engineering: a comprehensive review of applications, challenges, and prospects.

Tissue engineering, rooted in cell biology and materials science, focuses on repairing or replacing injured tissues and organs, offering groundbreakin...

Jun 1 2026 42226588
Artificial Intelligence for the Diagnosis of Pancreatic Diseases Using Endoscopic Ultrasonography.

Artificial intelligence (AI) is rapidly being applied to medical imaging; however, the evidence base for endoscopic ultrasonography-based AI (EUS-AI) ...

Jun 1 2026 42227807
AI-based Histologic Heterogeneity of Microvascular Obstruction at Cardiac MRI for Predicting MACEs: A Multicenter Study.

Background Microvascular obstruction (MVO) is strongly associated with adverse outcomes after ST-segment elevation myocardial infarction (STEMI). Howe...

Jun 1 2026 42227866
The role of infrared thermography in thyroid nodule detection and classification: a scoping review.

PURPOSE: To conduct a scoping review to assess the extent and type of evidence on the use of IRT as a diagnostic tool for thyroid nodule detection and...

Jun 1 2026 42228108
Identification of Pathological Secretions in Bronchoscopic Images Based on Edge Features and Multi-Scale Attention Mechanism.

The accumulation of pathological bronchial secretions compromises ventilation and oxygenation in critically ill patients and may lead to atelectasis o...

Jun 1 2026 42229724
Artificial intelligence-assisted urine cytology based on the Paris System for Reporting Urothelial Carcinoma.

BACKGROUND: Urine cytology is a noninvasive and valuable tool for detecting urothelial carcinoma but suffers from variable sensitivity and observer de...

Jun 1 2026 42223163
Physical Parameter-Guided Deep Learning Ultrasound Localization Microscopy Framework Based on Diffusion Model.

OBJECTIVE: Deep learning based-imaging methods have demonstrated significant potential for achieving high spatiotemporal resolution in Ultrasound Loca...

Jun 1 2026 42224314
Liver Nodule Anomaly Detection Using Ultra-sound Radiofrequency Signals and Variational Autoencoders.

OBJECTIVE: Detection of liver nodules in ultrasound (US) is challenging due to the low visibility in the presence of steatotic and cirrhotic livers. A...

Jun 1 2026 42224315
Universal and transferable attacks on pathology foundation models using microscopic perturbations.

The advent of foundation models initiated a paradigm shift in pathology and optical microscopy. However, these powerful systems also introduce vulnera...

Jun 1 2026 42225639
Conditional survival patterns and individualized prognostic prediction in malignant peritoneal mesothelioma.

Malignant peritoneal mesothelioma (MPM) is a rare, aggressive cancer with limited treatment options and extremely poor survival outcomes. Due to the d...

Jun 1 2026 42225935
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