Pathology

Fluorescence microscopy image classification of 2D HeLa cells based on the CapsNet neural network.

The development of computer technology now allows the quick and efficient automatic fluorescence microscopy generation of a large number of images of proteins in specific subcellular compartments using fluorescence microscopy. Digital image processing and pattern recognition technology can easily classify these images, identify the subcellular location of proteins, and subsequently carry out relat...

Synthesis, characterization, antimicrobial and antimetastatic activity of silver nanoparticles synthesized from Ficus ingens leaf.

Cancer incidence is still increasing due to inadequate responsive treatments. Inertness and biocompatibility of nanoparticles synthesized using plant extracts have shown therapeutic applications and make it to be a good anti-cancer candidates. This study is a recent novel spotlight that synthesized silver nanoparticle from Ficus ingens leaf extract (FILE) and studied its anti-metastatic and anti-b...

Detection of Extended-Spectrum β-Lactamase-Producing Escherichia coli Using Infrared Microscopy and Machine-Learning Algorithms.

The spread of multidrug resistant bacteria has become a global concern. One of the most important and emergent classes of multidrug-resistant bacteria...

Label-free classification of neurons and glia in neural stem cell cultures using a hyperspectral imaging microscopy combined with machine learning.

Due to a growing demand for a viable label-free observation method in the biomedical field, many techniques, such as quantitative phase imaging and Ra...

Predicting survival from colorectal cancer histology slides using deep learning: A retrospective multicenter study.

BACKGROUND: For virtually every patient with colorectal cancer (CRC), hematoxylin-eosin (HE)-stained tissue slides are available. These images contain...

A Computational Framework for Genome-wide Characterization of the Human Disease Landscape.

A key challenge for the diagnosis and treatment of complex human diseases is identifying their molecular basis. Here, we developed a unified computati...

Cellular cartography of the organ of Corti based on optical tissue clearing and machine learning.

The highly organized spatial arrangement of sensory hair cells in the organ of Corti is essential for inner ear function. Here, we report a new analyt...

Detection of Extraprostatic Extension of Cancer on Biparametric MRI Combining Texture Analysis and Machine Learning: Preliminary Results.

RATIONALE AND OBJECTIVES: Extraprostatic extension of disease (EPE) has a major role in risk stratification of prostate cancer patients. Currently, pr...

Elevated Serum Growth Differentiation Factor 15 Levels in Hyperthyroid Patients.

Recent studies have shown that growth differentiation factor 15 (GDF15), a member of the transforming growth factor-β (TGF-β)/bone morphogenetic prot...

Automatic thyroid nodule recognition and diagnosis in ultrasound imaging with the YOLOv2 neural network.

BACKGROUND: In this study, images of 2450 benign thyroid nodules and 2557 malignant thyroid nodules were collected and labeled, and an automatic image...

Estimating Prevalence, Demographics, and Costs of ME/CFS Using Large Scale Medical Claims Data and Machine Learning.

Techniques of data mining and machine learning were applied to a large database of medical and facility claims from commercially insured patients to d...

Fast ScanNet: Fast and Dense Analysis of Multi-Gigapixel Whole-Slide Images for Cancer Metastasis Detection.

Lymph node metastasis is one of the most important indicators in breast cancer diagnosis, that is traditionally observed under the microscope by patho...

OMeta: an ontology-based, data-driven metadata tracking system.

BACKGROUND: The development of high-throughput sequencing and analysis has accelerated multi-omics studies of thousands of microbial species, metageno...

Application of deep convolutional neural networks in classification of protein subcellular localization with microscopy images.

Single-cell microscopy image analysis has proved invaluable in protein subcellular localization for inferring gene/protein function. Fluorescent-tagge...

Accuracy of robot-assisted versus optical frameless navigated stereoelectroencephalography electrode placement in children.

OBJECTIVE The aim of this study was to compare the accuracy of optical frameless neuronavigation (ON) and robot-assisted (RA) stereoelectroencephalogr...

Adult Idiopathic Renal Fanconi Syndrome: A Case Report.

Renal Fanconi syndrome (RFS) is caused by generalized proximal tubular dysfunction and can be divided into hereditary and acquired form. Adult-onset R...

Biogenic synthesis of iron oxide nanoparticles via Skimmia laureola and their antibacterial efficacy against bacterial wilt pathogen Ralstonia solanacearum.

Plant diseases are threat to global food security. The excessive use of agrochemicals is the leading cause of pesticides resistance and toxicity to be...

Presence of gammaherpesvirus BoHV-4 in endometrial cytology samples is not associated with subclinical endometritis diagnosed at artificial insemination in dairy cows.

In the past, bovine herpesvirus 4 (BoHV-4) has been suggested to be associated with metritis and endometritis. However, not many field studies investi...

Molecularly imprinted polymer based quartz crystal microbalance sensor for the clinical detection of insulin.

In this study, quartz crystal microbalance sensors based on molecular imprinting technology were fabricated for real-time detection of insulin in aque...

Current Status of Magnetic Resonance Imaging in Patients with Malignant Uterine Neoplasms: A Review.

In this study, we summarize the clinical role of magnetic resonance imaging (MRI) in the diagnosis of patients with malignant uterine neoplasms, inclu...