Pathology

Latest AI and machine learning research in pathology for healthcare professionals.

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Multimodal US-gamma imaging using collaborative robotics for cancer staging biopsies.

PURPOSE: The staging of female breast cancer requires detailed information about the level of cancer spread through the lymphatic system. Common practice to obtain this information for patients with early-stage cancer is sentinel lymph node (SLN) biopsy, where LNs are radioactively identified for surgical removal and subsequent histological analysis. Punch needle biopsy is a less invasive approach...

Aug 9 2016 27507282

Deep learning based classification of breast tumors with shear-wave elastography.

This study aims to build a deep learning (DL) architecture for automated extraction of learned-from-data image features from the shear-wave elastography (SWE), and to evaluate the DL architecture in differentiation between benign and malignant breast tumors. We construct a two-layer DL architecture for SWE feature extraction, comprised of the point-wise gated Boltzmann machine (PGBM) and the restr...

Aug 6 2016 27529139
Molecular Properties of Drugs Interacting with SLC22 Transporters OAT1, OAT3, OCT1, and OCT2: A Machine-Learning Approach.

Statistical analysis was performed on physicochemical descriptors of ∼250 drugs known to interact with one or more SLC22 "drug" transporters (i.e., SL...

Aug 3 2016 27488918
Rod-based Fabrication of Customizable Soft Robotic Pneumatic Gripper Devices for Delicate Tissue Manipulation.

Soft compliant gripping is essential in delicate surgical manipulation for minimizing the risk of tissue grip damage caused by high stress concentrati...

Aug 2 2016 27584722
Dietary Omega-3 Polyunsaturated Fatty Acids Alter Fatty Acid Composition of Lipids and CYP2E1 Expression in Rat Liver Tissue.

Omega-3 polyunsaturated fatty acids (PUFAs) are used for the treatment and prevention of numerous pathologies in humans. As recently found, PUFAs play...

Jul 21 2016 27442787
Automatic entry point planning for robotic post-mortem CT-based needle placement.

INTRODUCTION: Post-mortem computed tomography guided placement of co-axial introducer needles allows for the extraction of tissue and liquid samples f...

Jul 15 2016 27421263
An image-guided automated robot for MRI breast biopsy.

BACKGROUND: The IGAR (Image-guided Automated Robot) is a robotic platform capable of performing highly accurate clinical interventions under image gui...

Jul 11 2016 27402476
Confirming an integrated pathology of diabetes and its complications by molecular biomarker-target network analysis.

Despite ongoing research into diabetes and its complications, the underlying molecular associations remain to be elucidated. The systematic identifica...

Jul 7 2016 27430657
A multiscale modelling of bone ultrastructure elastic proprieties using finite elements simulation and neural network method.

Bone is a living material with a complex hierarchical structure which entails exceptional mechanical properties, including high fracture toughness, sp...

Jul 5 2016 27480733
Image analysis and machine learning in digital pathology: Challenges and opportunities.

With the rise in whole slide scanner technology, large numbers of tissue slides are being scanned and represented and archived digitally. While digita...

Jul 4 2016 27423409
Machine Learning Techniques in Clinical Vision Sciences.

This review presents and discusses the contribution of machine learning techniques for diagnosis and disease monitoring in the context of clinical vis...

Jun 30 2016 27362387
Multispectral Fluorescence Imaging During Robot-assisted Laparoscopic Sentinel Node Biopsy: A First Step Towards a Fluorescence-based Anatomic Roadmap.

BACKGROUND: During (robot-assisted) sentinel node (SN) biopsy procedures, intraoperative fluorescence imaging can be used to enhance radioguided SN ex...

Jun 23 2016 27345689
Lung Cancer Detection Using Fuzzy Auto-Seed Cluster Means Morphological Segmentation and SVM Classifier.

An effective fuzzy auto-seed cluster means morphological algorithm developed in this work to segment the lung nodules from the consecutive slices of C...

Jun 14 2016 27299354
Computer-Aided Diagnosis of Micro-Malignant Melanoma Lesions Applying Support Vector Machines.

Background. One of the fatal disorders causing death is malignant melanoma, the deadliest form of skin cancer. The aim of the modern dermatology is th...

Jun 13 2016 27382567
Out-of-Sample Extrapolation utilizing Semi-Supervised Manifold Learning (OSE-SSL): Content Based Image Retrieval for Histopathology Images.

Content-based image retrieval (CBIR) retrieves database images most similar to the query image by (1) extracting quantitative image descriptors and (2...

Jun 6 2016 27264985
Effect of goat milk on hepatotoxicity induced by antitubercular drugs in rats.

Aim of the present study was to assess the hepatoprotective activity of goat milk on antitubercular drug-induced hepatotoxicity in rats. Hepatotoxicit...

Jun 2 2016 28911608
Antifungal activity of Momordica charantia seed extracts toward the pathogenic fungus Fusarium solani L.

Momordica charantia L., a vegetable crop with high nutritional value, has been used as an antimutagenic, antihelminthic, anticancer, antifertility, an...

Jun 2 2016 28911628
Dynamic cerebral reorganization in the pathophysiology of schizophrenia: a MRI-derived cortical thickness study.

BACKGROUND: A structural neuroanatomical change indicating a reduction in brain tissue is a notable feature of schizophrenia. Several pathophysiologic...

May 26 2016 27228263
Deep learning as a tool for increased accuracy and efficiency of histopathological diagnosis.

Pathologists face a substantial increase in workload and complexity of histopathologic cancer diagnosis due to the advent of personalized medicine. Th...

May 23 2016 27212078
Development of a compact continuum tubular robotic system for nasopharyngeal biopsy.

Traditional posterior nasopharyngeal biopsy using a flexible nasal endoscope has the risks of abrasion and injury to the nasal mucosa and thus causing...

May 18 2016 27230499
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