Pathology

Latest AI and machine learning research in pathology for healthcare professionals.

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[Research progress in artificial intelligence for the diagnosis and management of diseases in preterm infants].

Artificial intelligence (AI) technology is developing rapidly in the medical field, particularly showing significant clinical value in the diagnosis and management of diseases in preterm infants. Preterm infants have immature organ development and a high incidence of complications; early prediction, accurate diagnosis, and individualized treatment pose major clinical challenges. With its powerful ...

May 15 2026 42130365

Scientific highlights and perspectives from the International Inflammatory Breast Cancer Symposium 2025.

Inflammatory breast cancer (IBC) is a rare yet highly aggressive subtype of breast cancer, characterized by distinct clinical features, rapid progression, and complex biology. Despite decades of research, patient outcomes remain poor, underscoring the need for innovative approaches. The International IBC Symposium 2025 convened global experts to discuss advances in the field and to outline strateg...

May 15 2026 42133847
Mapping the Conformational Landscape of DNA Minicircles Through Atomic Force Microscopy and Shape Space Analysis.

The structural dynamics of DNA underpin essential biological processes, yet conventional structural biology methods often obscure conformational heter...

May 14 2026 42132089
The role of MRCP in characterizing ductal communication and high-risk features in pancreatic cystic lesions.

Pancreatic cystic lesions are increasingly detected due to the widespread use of high-resolution cross-sectional imaging, particularly MRI and CT. The...

May 14 2026 42133060
Artificial intelligence in small tissue biopsies: diagnostic applications, histochemical integration, and methodological challenges in surgical pathology.

Small tissue biopsies, including renal core biopsies, bone marrow trephines, gastrointestinal endoscopic samples, prostate needle cores, liver biopsie...

May 14 2026 42133091
A Bioinspired Three-Dimensional High-Curvature Nano-Interface Integrated Microfluidic Chip for Small Extracellular Vesicles Enrichment and Machine Learning-Assisted Prostate Cancer Precision Diagnosis.

The efficient and unbiased isolation of small extracellular vesicles (sEVs) from complex biological fluids remains a major obstacle for clinical diagn...

May 14 2026 42133268
From Flow to Feature Using a Proof-of-Concept Spectral-Driven Machine Learning Approach Using Smart Urinary and Drainage Catheter Systems: Algorithm Development and Validation.

BACKGROUND: Current urinary and drainage catheter systems collect fluids for visual inspection or manual sampling, offering limited diagnostic value w...

May 14 2026 42133567
VesiclePy: A machine learning vesicle analysis toolbox for volume electron microscopy.

Vesicles are critical components of neurons that package neurotransmitters and neuropeptides for their release, in order to communicate with other neu...

May 14 2026 42133697
Multimodal Fusion of Echocardiogram Images and Electronic Medical Records for Heart Disease Screening: Retrospective Algorithm Development and Validation Study.

BACKGROUND: Echocardiography is a fundamental imaging modality for the diagnosis of heart disease (HD), but its interpretation remains operator-depend...

May 14 2026 42133880
Cross-species insights from ART-D to uncover evolutionarily conserved oncogenic mechanisms.

Cancer arises from oncogenic clones, yet the dynamic mechanisms driving their stepwise evolution toward malignancy remain incompletely understood. Her...

May 14 2026 42135514
Rheology-driven penetration dynamics of needle-free jet injection in ex vivo porcine tissue.

Needle-free jet injectors offer promising capabilities for drug delivery; however, achieving precise, depth-targeted penetration remains a significant...

May 14 2026 42135551
Single-cell and machine learning reveal ROS-associated heterogeneity in hepatocellular carcinoma for precision medicine.

BACKGROUND: Reactive oxygen species (ROS) are critical regulators of tumor development and progression, yet their clinical significance and cellular m...

May 14 2026 42135662
An intelligent lung nodule classification model using 3D Trans-DenseUnet++-based lung nodule segmentation.

Lung nodule detectionis necessary for lung cancer treatment, which is crucial for treating the patients. However, the current dataset comprises only a...

May 14 2026 42128891
An automated workflow for fungal cell counting, cell size and data analysis: enhancing throughput and accuracy with the cell analysis and counting tool using ilastik software (caactus).

BACKGROUND: The development of filamentous fungal cells from spore to mature mycelium is influenced by a myriad of environmental conditions. Tradition...

May 13 2026 42129638
Non-Invasive Screening of AI-Assisted DNA Aneuploidy Cytology by Image Cytometry for the Early Diagnosis of Malignant Transformation of OPMDs.

INTRODUCTION AND AIMS: Oral exfoliative DNA aneuploidy cytology by image cytometry (DNA-ICM) has been introduced for the early diagnosis of malignant ...

May 13 2026 42134189
From EM to AI: Multiscale imaging of the secretory pathway with insights from plant cells.

The secretory pathway is a central and evolutionarily conserved feature of eukaryotic cells, responsible for protein and lipid trafficking, membrane b...

May 13 2026 42126394
Urban river health evaluation in semi-arid Xi'an, China: a hybrid RF-DNN framework integrating multi-source and SHAP-based interpretability.

Rapid urbanization in semi-arid regions subjects metropolitan rivers to a distinctive form of hydrologic-physical impairment-herein designated as Type...

May 13 2026 42126479
Artificial intelligence for keratosis characterization and identification of lichenoid lesions in histological samples of oral leukoplakia.

Oral leukoplakia (OL) is a precancerous condition typically assessed through histopathological examination of mucosal lesion biopsies. Identifying his...

May 13 2026 42126591
Multimodality Imaging in Myocarditis: Integrating Etiology, Diagnosis, and Risk Stratification.

PURPOSE OF REVIEW: Myocarditis presents with heterogenous clinical manifestations and remains diagnostically challenging due to nonspecific biomarkers...

May 13 2026 42126698
Semen RNA-Based Biomarkers for Prostate Cancer Detection and Risk Stratification: A Prospective Multi-Center Validation Study.

OBJECTIVE: To assess the diagnostic performance of semen RNA-based biomarkers for detecting prostate cancer and differentiating cancer grade groups. M...

May 13 2026 42127322
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