Pathology

Latest AI and machine learning research in pathology for healthcare professionals.

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A decision-oriented framework for genomic testing across the prostate cancer continuum.

Genomic testing is now embedded in contemporary prostate cancer care, yet the clinical meaning of di...

(1)
Jun 2026 42251787
A systemic immune signature stratifies early-stage breast cancer patients and reveals soluble IL-2RA and PD-1 as potential independent prognostic biomarkers.

BACKGROUND: Breast cancer (BC) is the most common cancer in women and the leading cause of cancer-re...

(2)
Jun 2026 42244007
Advancement of deep learning models with whole slide image in diagnosis, subtyping and prognosis for glioma.

Gliomas are heterogeneous primary central nervous system (CNS) tumors with diverse molecular subtype...

Jun 2026 42246131
Multi-omics analysis identifies CD48 and ITIH5 as potential diagnostic biomarkers and therapeutic targets for metabolic disorders associated with obesity.

BACKGROUND: Obesity-driven metabolic disorders involve pathological remodeling of white adipose tiss...

Jun 2026 42248268
Navigating PI-RADS v2.1 in clinical practice: pitfalls, variability, and the supportive role of AI.

Prostate Imaging Reporting and Data System (PI-RADS) version 2.1 has substantially advanced the stan...

Jun 2026 42240644
Decoding Occult Cervical Lymph Node Metastasis in Head and Neck Squamous Cell Carcinoma: From AI-Driven Multimodal Fusion to Clinical Translation.

PURPOSE OF REVIEW: This review examines the limitations of conventional macroscopic approaches in de...

Jun 2026 42240903
Smartphone-Based Proactive Self-Screening for Ocular Surface Malignancies: A Nonrandomized Clinical Trial.

IMPORTANCE: Ocular surface malignancies pose risks to vision and survival yet are frequently misdiag...

Jun 2026 42240998
Integrating morphology and molecular biology: AI-driven molecular prediction in Pathology with a focus on Cytology.

BACKGROUND: Recent computational pathology research proposes using artificial intelligence to infer ...

Jun 2026 42241369
Histopathological Assessment of Myocardial Ischemia-Reperfusion Injury Using Transformer-Based Artificial Intelligence: Model Comparison Study.

BACKGROUND: Myocardial ischemia-reperfusion injury (MIRI) poses diagnostic challenges due to complex...

Jun 2026 42241702
DEHP-induced male reproductive toxicity: Evidence from population studies, animal experiments, and multi-omics profiling.

OBJECTIVE: To evaluate the association between di(2-ethylhexyl) phthalate (DEHP) exposure and testos...

(4)
Jun 2026 42241798
Diagnostic yield and cost of three-level H&E sectioning in prostate biopsies.

AIM: The traditional three-level H&E sectioning protocol for prostate biopsies was developed for ult...

(1)
Jun 2026 42242896
Essential Data Elements for Laboratory Test Interoperability: An Expert Consensus-Based Framework.

The increasing digitalization of healthcare necessitates laboratory data interoperability to ensure ...

Jun 2026 42236319
CT-based deep learning radiogenomics for predicting key glioma genotypes (IDH, ATRX, EGFR, TP53).

PURPOSE: Molecular subtyping guides diagnosis and targeted therapy for gliomas. Although MRI-the cur...

(1)
Jun 2026 42236611
A comparative analysis of deep learning models for disease classification in multi-organ histopathological images.

Histopathological whole slide images (WSIs) provide critical information for disease diagnosis, yet ...

(2)
Jun 2026 42236837
Contrastive adapter training and consensus knowledge distillation for multi-source-free domain adaptation in skin cancer diagnosis.

Skin cancer diagnosis, particularly the differentiation of melanoma from benign nevi, is a vital yet...

Jun 2026 42247734
Beyond attention heatmaps: How to get better explanations for multiple instance learning models in histopathology.

Multiple instance learning (MIL) has enabled substantial progress in computational histopathology, w...

(1)
Jun 2026 42263498
Multi-omic biomarkers of neoadjuvant treatment response in rectal cancer: A narrative review.

BACKGROUND: Neoadjuvant treatment response in rectal cancer is highly heterogeneous, complicating pa...

Jun 2026 42250371
Epigenetic reprogramming of tissue-resident memory T cells in chronic inflammatory disorders and implications for targeted therapies.

BACKGROUND: Tissue-resident memory T (TRM) cells play a role in causing long-term tissue injury in c...

(1)
Jun 2026 42233398
Extracellular Vesicles in Exhaled Breath Condensate as Emerging Biomarkers in Lung Cancer.

Exhaled breath condensate (EBC) has emerged as a noninvasive liquid biopsy medium that captures aero...

(1)
Jun 2026 42233525
Comparison of volume- and surface-based magnetic resonance imaging morphometry algorithms in the detection of focal cortical dysplasia.

OBJECTIVE: Detection of focal cortical dysplasia (FCD) remains a major challenge in presurgical epil...

Jun 2026 42233975
An artificial intelligence solution for evaluation of prostate needle core biopsy specimens: impact in a non-specialist setting.

The diagnosis of prostate cancer rests on the histopathological evaluation of prostate needle core b...

Jun 2026 42234114
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