Latest AI and machine learning research in pathology for healthcare professionals.
PURPOSE: Intracranial calcifications are commonly found in adults and may represent either benign or pathological lesions. Conventional imaging modalities detect static macrocalcifications but do not capture molecular microcalcification. In this study, we used 18F-sodium fluoride (NaF) PET/computed tomography (CT) to idetect intracranial molecular microcalcification. METHODS: A total of 127 subjec...
Label-free detection of microRNAs (miRNAs) has emerged as a pivotal approach in molecular diagnostics, integrating the programmability of CRISPR systems with the high sensitivity of nanomaterial-based transduction. miRNAs are short, noncoding RNAs that play central roles in gene regulation and disease pathogenesis, serving as valuable biomarkers for early diagnosis and prognosis. Conventional miRN...
Infertility has emerged as an increasingly serious global public health concern, affecting approximately one in six individuals of reproductive age wo...
BACKGROUND: Approximately one-fourth of patients with clinical stage I testicular cancer relapse. For decades, risk stratification has been based on d...
OBJECTIVE: This study aimed to evaluate the coherence between data heterogeneity and model complexity by comparing seven convolutional neural network ...
Laparoscopic cholecystectomy is the gold standard for treating symptomatic gallstones. Despite established safety strategies, variability in their ado...
Focal therapy offers a middle ground between active surveillance and whole-gland treatment for patients with low- and intermediate-risk prostate ...
Breast cancer (BC) represents the most common and one of the most lethal malignancies among women globally, ranking second only to lung cancer in term...
Esophageal squamous cell carcinoma (ESCC) lacks a standardized classification system, resulting in inconsistent clinical management and a suboptimal p...
BACKGROUND: Early and accurate classification of breast tumors from MRI scans is essential for improving patient outcomes. However, a key limitation o...
Postoperative recurrence and metastasis in esophageal squamous cell carcinoma (ESCC) are closely associated with cancer stem cells (CSCs), though the ...
Hepatocellular carcinoma (HCC) is a leading cause of cancer-related mortality. It is often diagnosed at advanced stages and characterized by high recu...
Recent advances in three-dimensional single-cell-resolution imaging have begun to link organ-wide and cellular-level research in development and disea...
BACKGROUND: Cutaneous T-cell lymphomas (CTCLs) are a heterogeneous group of non-Hodgkin lymphomas, with mycosis fungoides (MF) being the most common t...
Follicles comprised of oocytes and surrounding cells are essential for reproductive function. They are fixed before birth and decrease thereafter thro...
Understanding electric-field-induced phase transitions is crucial for optimizing the ferroelectric and antiferroelectric properties of hafnium zirconi...
Radiation necrosis (RN) remains a challenging complication of upfront radiation therapy for both brain metastases and primary tumors. Despite developm...
Monoclonal gammopathies span a continuum from monoclonal gammopathy of undetermined significance (MGUS) and smoldering multiple myeloma (SMM) to overt...
PURPOSE: Differentiating conjunctival intraepithelial neoplasia (CIN) from pterygium and pseudopterygium remains clinically challenging, especially in...
OBJECTIVE: Aspartame, a widely used artificial sweetener, has attracted increasing attention for its potential systemic and oral toxicity. However, th...