Pathology

IGSF9 drives malignant transformation and predicts early-stage lung adenocarcinoma in integrated transcriptomic analyses.

PURPOSE: Lung adenocarcinoma (LUAD), the most common subtype of non-small cell lung cancer (NSCLC), ...

Bulk and single-cell transcriptome analyses combined with molecular simulations identify ferritinophagy as a key target for resveratrol in osteoarthritis.

The pathophysiology of osteoarthritis (OA), a common degenerative joint disease, is complicated. The...

Machine learning classification of normal and malignant cells on the basis of their viscoelastic properties.

BACKGROUND AND OBJECTIVE: Cell mechanics, elasticity and viscoelasticity, are key markers of biologi...

Deep transfer learning radiomics combined with explainable machine learning for predicting malignancy risk in parotid gland tumors based on ultrasound.

OBJECTIVE: This study aimed to develop and validate an ultrasound (US)-based deep transfer learning ...

Whole-body molecular and cellular mapping of the laboratory mouse.

The laboratory mouse is a key model system for biomedical research, yet body-wide measurement tools ...

Artificial intelligence-assisted three-dimensional imaging of breast microinvasive carcinoma reveals larger invasive focus size in a substantial proportion of cases.

Microinvasive carcinoma of breast is a unique type of malignancy characterized by the presence of sm...

Dental Odontogenic Lesion CBCT and Histopathology Integrated Dataset for Benchmarking Deep Learning Algorithms.

Accurate diagnosis of odontogenic lesions requires pre-operative cone-beam computed tomography (CBCT...

Quantitative pathology and APOE genotype reveal dementia risk and progression in Lewy body disease.

Dementia in Lewy body diseases (LBD) is common and arises through heterogeneous and incompletely und...

Artificial Intelligence for Colorectal Surgeons - Part I: Foundations, Clinical and Educational Applications.

BACKGROUND: Artificial intelligence (AI) is rapidly transforming colorectal surgery through applicat...

Natural Language Processing Methods Automate Molecular Marker Extraction From Glioma Pathology Reports.

BACKGROUND AND OBJECTIVES: Molecular markers such as isocitrate dehydrogenase (IDH) and alpha-thalas...

Deep Learning Enables Pixel-Level Nanoparticle Distribution Mapping in Routine Histological Sections by Integrating Cancer Associated Fibroblasts Features.

The efficient accumulation and uniform distribution of nanomedicine within tumors are critical for a...

Artificial Intelligence and Multiomics Beyond PSA Screening in African and Middle Eastern Prostate Cancer Patients.

Prostate cancer (PCa) remains a major global health burden, with incidence rising as populations age...

Artificial intelligence-assisted FTIR spectroscopy for hormone receptor subtyping in formalin-fixed breast Cancer tissues.

BACKGROUND: Determination of estrogen receptor (ER) and progesterone receptor (PR) status is critica...

GHMS-CycleGAN: Graph-Based Hierarchical Multi-stain CycleGAN for Stain Normalization and Classification in Digital Pathology.

The emergence of digital pathology (DP) has provided numerous computer-aided diagnosis (CAD) opportu...

Physics-based simulation of ultrasound propagation from MRI volumes for cross-modal breast imaging.

BACKGROUND: Magnetic resonance imaging (MRI) of breast tissue is often used to definitively diagnose...

Molecularly Engineered SERS Platform with Microturbulence-Enhanced Electrohydrodynamics for Multiplexed Profiling of Lung Cancer ctDNA.

Precise profiling of multiple circulating tumor DNA (ctDNA) is hindered by the challenge of resolvin...

Technical Description of the Mini Far-Lateral Approach: A Refined, Stability-Preserving Corridor to the Petroclival Region.

BACKGROUND AND OBJECTIVES: The far-lateral approach remains essential for accessing ventral and vent...

Enhancing drug synergy in malignant diseases with deep architecture optimization algorithms.

Malignant diseases remain one of the leading causes of death globally. Drug synergy has emerged as a...

Artificial Intelligence and Nasal Cytology: Toward a Comprehensive Cytological Endotyping of Rhinitis.

Comparison of breast ultrasound image classification accuracy between convolutional neural networks and human experts using multicenter external validation cohort data.

PURPOSE: In recent years, much research has been conducted on ultrasound diagnosis of breast tumors ...

Contemporary Indications and Technical Limits of Transoral Laser Microsurgery for Laryngeal Squamous Cell Carcinoma.

Transoral laser microsurgery (TOLMS) is an established organ-preserving treatment for early-stage an...