Pathology

Latest AI and machine learning research in pathology for healthcare professionals.

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Artificial intelligence-based classification of Spitz tumors.

Spitz tumors are diagnostically challenging due to overlap in atypical histological features with conventional melanomas. We investigated to what extent artificial intelligence (AI) models, using histological and/or clinical features, can: (1) distinguish Spitz tumors from conventional melanomas; (2) predict the underlying genetic aberration of Spitz tumors; and (3) predict the diagnostic category...

Feb 16 2026 41847156

Computer Vision for Preoperative Soft-Tissue Landmarking in Cleft Lip Repair: A Systematic Review.

BACKGROUND: Cleft lip repair presents complex surgical challenges requiring precise preoperative planning. Emerging computer vision technologies powered by artificial intelligence (AI) may support more consistent and accurate surgical assessments. This systematic review defines the scope, methods, and performance of computer vision for preoperative soft-tissue landmarking in cleft lip repair. METH...

Feb 16 2026 41701135
Recent Advances in Cancer Diagnostics: Exotic Animal Medicine and Beyond.

Recent advances in veterinary diagnostic oncology have significantly improved neoplasia detection in animals, including zoo, exotic, and wildlife spec...

Feb 16 2026 41702787
Harnessing artificial intelligence in gastrointestinal endoscopy for early detection of dysplastic lesions in inflammatory bowel disease.

Artificial intelligence (AI) has become an increasingly valuable tool in gastrointestinal endoscopy, especially in the context of inflammatory bowel d...

Feb 16 2026 41700159
Multicenter Clinical Validation of an Artificial Intelligence Diagnostic Classification Model for Laryngoscopy Images.

OBJECTIVE: To develop and externally validate a computer-aided diagnosis (CADx) model using artificial intelligence (AI) for classifying laryngeal les...

Feb 16 2026 41696998
Title: AI-based quantification of tumor-infiltrating lymphocytes with integrative transcriptomics in ovarian clear cell carcinoma: JGOG3025-TR1/A1 study.

Transcriptomic classification methods have been proposed for ovarian clear cell carcinoma. However, their clinical significance and association with p...

Feb 16 2026 41697393
CT-based subregional and peritumoral radiomics for predicting pathological T stage of clear cell renal cell carcinoma: an exploratory study of biological mechanisms.

OBJECTIVES: To evaluate intratumoral subregional and peritumoral radiomics for predicting pathological T stage of clear cell renal cell carcinoma (ccR...

Feb 16 2026 41697559
Digital pathology-based artificial intelligence algorithms in prostate cancer: inside the 'black box'.

Artificial intelligence (AI) algorithms leveraging digital pathology slides are currently transforming the way urological cancers are diagnosed and gr...

Feb 16 2026 41698677
Utilisation of intramuscular and intermuscular fat to develop a new skeletal muscle grading score which can predict treatment outcomes for locally advanced rectal cancer.

BACKGROUND: Sarcopenia has been widely studied in rectal cancer with increasing evidence to suggest that other body composition parameters, in particu...

Feb 16 2026 41692917
Breathomics Analysis for Early Diagnosis of Lung Cancer Based on PTR-TOF MS: A Large Sample Size Cross-Sectional Study.

INTRODUCTION: Lung cancer remains a leading cause of cancer mortality globally, emphasising the critical need for non-invasive and cost-effective earl...

Feb 15 2026 41693114
Risk prediction for chronic atrophic gastritis using a random forest model: A multicenter study.

BACKGROUND: Chronic atrophic gastritis (CAG) is a significant precancerous condition of gastric cancer (GC). CAG often lacks typical symptoms in its e...

Feb 15 2026 41695920
Computational Modeling Meets 3D Bioprinting: Emerging Synergies in Cardiovascular Disease Modeling.

Cardiovascular diseases (CVDs) remain the leading cause of death worldwide, underscoring the need for improved strategies in diagnosis, treatment, and...

Feb 15 2026 41691381
Dental Students' Knowledge, Attitudes and Perceptions of Artificial Intelligence Tools to Aid in the Diagnosis of Oral Cancer and Oral Potentially Malignant Disorders.

BACKGROUND: Artificial intelligence (AI) has emerged as a promising tool in dentistry, particularly in the early detection of oral cancer (OC) and ora...

Feb 15 2026 41692680
Toward Timely Diagnosis of Pancreatic Cancer: Revolutionizing Early Detection Through Genomics, Artificial Intelligence, and Noninvasive Biomarkers.

BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) remains one of the most aggressive cancers, typically diagnosed at an advanced stage due to its su...

Feb 15 2026 41692706
Multimodal hybrid mamba classification model for tumor pathological grade prediction using magnetic resonance images.

Malignant tumors present a significant global health challenge, and accurate pathological grading is essential for personalized treatment. Traditional...

Feb 14 2026 41719867
H-DCA Net: Hierarchical dual-branch coordinate attention framework for multi-scale gastric histopathology diagnosis.

BACKGROUND AND OBJECTIVE: Early and accurate diagnosis of gastric cancer is crucial for improving patient prognosis. However, conventional histopathol...

Feb 14 2026 41722294
Deep learning for histopathological diagnosis of esophageal squamous cell carcinoma in biopsies: A multicenter analysis.

BACKGROUND: Esophageal squamous cell carcinoma (ESCC) is a major cause of cancer mortality in Asia, where histopathological diagnosis of endoscopic bi...

Feb 14 2026 41692642
Kinic index: an artificial intelligence-driven predictive model and multitarget drug discovery framework for hepatocellular carcinoma patients.

Hepatocellular carcinoma (HCC) remains a major global health challenge due to its molecular heterogeneity, late diagnosis, and limited therapeutic opt...

Feb 14 2026 41691080
An interpretable machine learning model for preoperative prediction of aldosterone secretion and CYP11B2 status of adrenal gland.

BACKGROUND: To investigate whether a machine learning (ML) model integrating CT-based radiomics and clinical features can noninvasively evaluate the a...

Feb 14 2026 41691226
Interpretable habitat and peritumoral radiomics from multiparametric MRI for preoperative high-risk prostate cancer prediction: a multi-institutional study.

BACKGROUND: Current preoperative assessment faces limitations, including PI-RADS scoring subjectivity and diagnostic uncertainty in distinguishing hig...

Feb 14 2026 41691237
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