Latest AI and machine learning research in pathology for healthcare professionals.
Placental insufficiency affects five to ten% of pregnancies worldwide, and folate deficiency has emerged as a key contributing factor. The molecular pathways linking folate metabolism to placental pathology remain poorly characterized. We developed a heterogeneous graph neural network framework that integrates genomic, transcriptomic, proteomic, and metabolomic data to investigate these mechanisms...
Hyperspectral imaging (HSI) is a three-dimensional imaging technique that integrates spectroscopy and imaging. When combined with microscopy, hyperspectral microscopic imaging (HMI) captures rich spatial-spectral information at the cellular scale, offering new avenues for histopathological analysis. Conventional pathological diagnosis relies on manual inspection of stained slides, which is time-co...
BACKGROUND AND AIMS: EGD remains the primary diagnostic modality for evaluating lesions of the upper gastrointestinal (UGI) tract. This meta-analysis ...
Oral cancer and oral potentially malignant disorders (OPMDs) remain a significant challenge in diagnosis and therapy, primarily due to inherent limita...
This data article presents a structured dataset from the transfer of a proven PVDF hollow-fiber formulation to macro-porous PVDF flat sheet membranes ...
Phenotypic heterogeneity is a defining feature of bacterial stress responses, long framed as irreducible noise arising from stochastic molecular event...
BACKGROUND: Idiopathic Pulmonary Fibrosis (IPF) is a progressive and fatal interstitial lung disease characterized by excessive extracellular matrix (...
Interactions between cells are central to tissue organization and function in health and disease. Labeling immune partnerships by sortagging intercell...
Intestinal parasitic infections (IPIs) have a worldwide distribution and have a major impact on health, work capacity, and economy in many countries. ...
Multimodal profiling of inflammatory bowel disease (IBD) patient tissue and blood samples has revealed the disease spectrum in unprecedented detail, a...
Intracranial aneurysms (IAs) are severe cerebrovascular disorders lacking effective gene therapy or pharmacological interventions. Vascular smooth mus...
Ulcerative colitis (UC) is a chronic inflammatory bowel disease characterized by persistent mucosal inflammation. While fibroblasts contribute to tiss...
OBJECTIVES: The study aimed to assess the predictive performance of transition zone PSA density (TZ-PSAD) compared to conventional PSA density (PSAD) ...
Light-sheet fluorescence microscopy (LSFM) has emerged as a revolutionary imaging modality for investigating intact three-dimensional brain structures...
The occurrence and development of a wide range of preeclampsia (PE), especially early-onset preeclampsia (EOPE), is closely associated with the immune...
Conventional approaches for vascular graft stenosis diagnostics, including X-ray angiography, magnetic resonance imaging and Doppler ultrasound, altho...
Spatial transcriptomics technologies profile gene expression across tissue sections while retaining spatial information, yet most platforms capture si...
BACKGROUND: Hepatocellular carcinoma (HCC) is one of the most common malignant liver tumor with poor clinical outcomes. Accumulated evidence has demon...
Early detection of esophageal cancer (EC) remains a major challenge due to the limited understanding of its initial molecular alterations. Therefore, ...
Synovial fluid analysis remains to be a critical aspect of the diagnosis of crystal arthropathies. The gold standard, compensated polarized light micr...