Pathology

Latest AI and machine learning research in pathology for healthcare professionals.

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MyoClass: A modular multimodal auto-classification system for myocardial tissue characterization.

Differentiating myocarditis from myocardial infarction (MI) using Cardiac Magnetic Resonance (CMR) imaging remains a significant clinical challenge due to overlapping imaging and clinical presentations. We propose MyoClass, a deep learning (DL)-based framework that integrates multimodal CMR sequences (CINE, Late Gadolinium Enhancement (LGE), Modified Look-Locker Inversion Recovery (MOLLI)), Left V...

Mar 14 2026 41831142

A Smartphone-based Comprehensive Dataset of Annotated Oral Cavity Images for Enhanced Oral Disease Diagnosis.

This study introduces a SMARTphone-based, expert annotated dataset of Oral Mucosa images (SMART-OM), collected to facilitate the development of Artificial Intelligence and Machine Learning (AI/ML) technologies for automated diagnosis of Oral Cancer (OC) and Oral Potentially Malignant Disorders (OPMD). The dataset consists of 2,469 images from 331 subjects from four distinct classes: healthy/normal...

Mar 13 2026 41826371
A Machine learning pipeline to investigate tissue ingrowth in cerebral aneurysms using preclinical animal models.

Cerebral aneurysm is a life-threatening condition characterized by the formation of a saccular bulge in brain blood vessels, which can rupture and lea...

Mar 13 2026 41826635
An explainable radiomics model based on multiparametric magnetic resonance for differentiating benign and malignant orbital tumors.

OBJECTIVE: To develop and internally test a multiparametric radiomics combined model for differentiating benign and malignant orbital tumors. PATIENTS...

Mar 13 2026 41826882
Practical AI-based cell extraction and spatial statistics for large 3D bone marrow tissue images.

Although the molecular regulation of hematopoiesis is well characterized, the spatial organization of hematopoietic cells within bone marrow (BM) rema...

Mar 13 2026 41831446
Refining prognostication in non-muscle-invasive bladder cancer: From clinical models to artificial intelligence.

Over the past 2 decades, risk stratification in non-muscle-invasive bladder cancer (NMIBC) has evolved considerably, progressing from simple clinico-p...

Mar 13 2026 41832109
Improving visibility of small anatomical details on low and ultra-low dose computed tomography with artificial intelligence-based image reconstructions.

To assess how computed tomography (CT) image reconstruction techniques affect perceived diagnostic image quality at varying radiation dose levels in c...

Mar 13 2026 41821465
Overview of combined adjuvant strategies for tumor biomarker detection.

Cancer is one of the leading causes of death worldwide, and early tumor detection can significantly reduce mortality rates. Liquid biopsy is a minimal...

Mar 13 2026 41823325
Decoding epilepsy's molecular blueprint: Machine learning unravels transcriptomic subtypes and regulatory networks.

OBJECTIVE: Drug-resistant epilepsy (DRE) affects approximately one-third of patients with epilepsy. The molecular heterogeneity underlying DRE remains...

Mar 13 2026 41823335
The Performance of Artificial Intelligence in Classifying Molecular Markers in Adult-Type Gliomas Using Histopathological Images: Systematic Review.

BACKGROUND: Adult-type gliomas are among the most prevalent and lethal primary central nervous system tumors, where prompt and accurate diagnosis is e...

Mar 13 2026 41824546
Whole-Body Transformation in Obese Patients Undergoing Metabolic Surgery: Insights From Automated Multiorgan Segmentation.

PURPOSE: This study assesses whether automated segmentation allows evaluation of subtle changes in volume and intrinsic tissue characteristics in an o...

Mar 12 2026 41856817
Idiopathic pulmonary fibrosis from a multiscale mechanobiology perspective: Mechanisms and future therapeutic prospects.

Idiopathic pulmonary fibrosis (IPF) is a fatal interstitial lung disease that induces irreversible fibrosis and architectural remodeling. Traditional ...

Mar 12 2026 41940333
Illuminating the Invisible: Translational Molecular Imaging in Cardiovascular Medicine.

Cardiovascular disease remains the predominant cause of global morbidity and mortality, with recent epidemiological trends indicating a resurgence in ...

Mar 12 2026 41818327
J³SPM AI: An integrated open-source platform for AI-assisted image analysis and image-guided workflows in scanning probe microscopy.

Scanning probe microscopy (SPM), particularly atomic force microscopy (AFM), is essential for characterizing materials at the nanometer scale. However...

Mar 12 2026 41831346
Based on WGCNA and machine learning studies, SMURF2 drives NSCLC malignant transformation, ferroptosis, and macrophage polarization by ubiquitinating SPP1.

BACKGROUND: Non-small cell lung cancer (NSCLC) is a common type of lung cancer with poor prognosis and high mortality in advanced stages. Although sec...

Mar 12 2026 41831581
Tissue-resolved molecular landscape reveals hepatic regulatory networks and metabolic mediators underlying feed efficiency in chickens.

INTRODUCTION: Residual feed intake (RFI) is a key indicator of feed efficiency in poultry and is regulated by coordinated physiological processes acro...

Mar 12 2026 41831681
Artificial intelligence assisted multi-model pathological diagnosis of breast cancer based on multispectral autofluorescence images.

Virtual staining technology offers a promising solution to overcome the time-consuming and sample-consumption nature of conventional histochemical sta...

Mar 12 2026 41820369
Machine Learning Prediction of Vaginal Tissue Tears Using Finite Element Simulations Informed by Planar Biaxial Testing.

PURPOSE: Vaginal tissue tearing during childbirth is a prevalent injury with potential long-term consequences, yet the mechanical factors influencing ...

Mar 12 2026 41820774
Detection of Lung and Colon Cancer Using XRx-Net With Histopathological Images.

Lung and Colon Cancer (LCC) is a prevalent type of cancer influenced by factors such as genetics, smoking, second-hand smoke exposure, and alcohol con...

Mar 12 2026 41821248
Ontology-aware DNA methylation classification with a curated atlas of human tissues and cell types.

DNA methylation is a key regulatory mechanism reflecting both short- and long-term biological stimuli. While it has been widely used to study aging th...

Mar 12 2026 41825448
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