Latest AI and machine learning research in pathology for healthcare professionals.
Volume electron microscopy (vEM) is a powerful technique that enables 3D visualization of biological structures at the nanometer scale. However, vEM imaging relies on sequential scanning of 2D images, and due to section thickness limitations, the axial resolution is significantly lower than the lateral resolution. In this paper, we propose the vEMINR, an ultra-fast isotropic reconstruction method ...
Primary liver cancer, mainly hepatocellular carcinoma and intrahepatic cholangiocarcinoma, remains a leading cause of cancer mortality worldwide. Early detection is crucial for curative treatment, yet current surveillance and diagnostic strategies, primarily ultrasound surveillance and contrast-enhanced CT or MRI, suffer from operator dependence, limited sensitivity, and interpretive variability. ...
Voxel-based morphometry (VBM), a popular approach in neuroimaging research, uses magnetic resonance imaging data to assess variations in the local den...
BACKGROUND: Transcriptomic profiling technologies have advanced the analysis of biological and toxicological responses. However, substantial differenc...
These guidelines provide a clear and practical framework for the effective implementation of digital pathology (DP) in routine anatomical pathology pr...
PURPOSE OF REVIEW: Microvascular inflammation (MVI) is a central feature of allograft rejection, traditionally associated with antibody-mediated rejec...
BACKGROUND: Prostate cancer (PCa) diagnosis has historically relied on prostate-specific antigen (PSA) testing. Although PSA screening significantly r...
BACKGROUND: Thrombotic thrombocytopenic purpura (TTP) is a rare but life-threatening thrombotic microangiopathy, with a substantial risk of relapse de...
With the increasing development of deep learning solutions for fluorescence microscopy image analysis, there is a growing demand for annotated ground ...
UNLABELLED: Pulmonary nodules are a common radiological finding that can be classified as either benign or Malignant, with significant clinical implic...
Neuroblastoma is the most prevalent extracranial solid tumor in pediatric age populations worldwide and the most common neoplastic disease diagnosed i...
Sickle cell disease (SCD), a monogenic disorder arising from a single point mutation in the β-globin gene, continues to pose a significant global heal...
BACKGROUND: N-(1,3-dimethylbutyl)-N'-phenyl-p-phenylenediamine-quinone (6PPD-Q), a transformation product of tire rubber antioxidants, has been increa...
In Alzheimer's disease (AD), pathological tau protein shows a progressive accumulation of post-translational modifications (PTMs), reflecting disease ...
Type 2 diabetes mellitus (T2DM) is a chronic metabolic disease, while non-alcoholic fatty liver disease (NAFLD) is the most prevalent chronic liver di...
BACKGROUND & AIMS: Clinical outcomes and histological characteristics of biopsy-proven steatotic liver disease (SLD) subtypes remain understudied. We ...
Thickness measurement of two-dimensional (2D) materials is essential due to their thickness-dependent physical and optical properties. However, curren...
Innovation in biomaterials has brought both breakthroughs and challenges in medicine, as implant materials have become increasingly multifunctional an...
Rectal cancer management has increasingly shifted toward organ-preserving strategies that aim to maintain oncologic control while preserving bowel, ur...
OBJECTIVE: This study aimed to clarify the molecular mechanisms through which nicotine (Nic) aggravates ischemic stroke (IS), with an emphasis on infl...