PCI

Soft robotic in the construction of prosthetic heart valve: a novel approach.

In this study, we describe the design, fabrication and computational testing of a new prosthetic device for aortic valve replacement. The device is an active stent composed of a silicone rubber during initial prototyping, with adaptation towards a hydrogel, poly-vinyl alcohol reinforced with bacterial cellulose nanofibres underway. The nature of the stent is soft robotic (SR), where an increase in...

Same same but different: A Web-based deep learning application revealed classifying features for the histopathologic distinction of cortical malformations.

OBJECTIVE: The microscopic review of hematoxylin-eosin-stained images of focal cortical dysplasia type IIb and cortical tuber of tuberous sclerosis complex remains challenging. Both entities are distinct subtypes of human malformations of cortical development that share histopathological features consisting of neuronal dyslamination with dysmorphic neurons and balloon cells. We trained a convoluti...

Detecting vulnerable plaque with vulnerability index based on convolutional neural networks.

Plaque rupture and subsequent thrombosis are major processes of acute cardiovascular events. The Vulnerability Index is a very important indicator of ...

Machine Learning to Predict Stent Restenosis Based on Daily Demographic, Clinical, and Angiographic Characteristics.

BACKGROUND: Machine learning (ML) has arrived in medicine to deliver individually adapted medical care. This study sought to use ML to discriminate st...

How to manage a partial detachment of the ureter during robotic radical prostatectomy?

The management of a ureteral orifice injury occurring during robotic radical prostatectomy (RARP) represents a challenge for urologists. Several techn...

A Catheter-Deployable Soft Robotic Inflatable Basket for Enhanced Conformability to the Left Atrium of the Heart.

This paper presents the design, fabrication, and test results for a novel basket catheter that utilizes soft robotic technology, which can conform to ...

Predicting Chronic Subdural Hematoma Recurrence and Stroke Outcomes While Withholding Antiplatelet and Anticoagulant Agents.

The aging of the western population and the increased use of oral anticoagulation (OAC) and antiplatelet drugs (APD) will result in a clinical dilemm...

Serum amyloid A4 is a procoagulant apolipoprotein that it is elevated in venous thrombosis patients.

BACKGROUND: Serum amyloid A4 (SAA4) is an apolipoprotein that is in the SAA family and it is constitutively translated. Previously, acute-phase SAA1 a...

Propagation of uncertainty in the mechanical and biological response of growing tissues using multi-fidelity Gaussian process regression.

A key feature of living tissues is their capacity to remodel and grow in response to environmental cues. Within continuum mechanics, this process can ...

Therapeutic Anticoagulation With an Ultra-Low Concentration Argatroban-Based Purge Solution for Percutaneous Ventricular Assist Device in Patient With Heparin-Induced Thrombocytopenia.

Percutaneous left ventricular assist devices (pVADs) require a continuous purge solution containing heparin to prevent pump thrombosis and device fai...

Rapid Manufacturing of Thin Soft Pneumatic Actuators and Robots.

This protocol describes a method for rapid manufacturing of soft pneumatic actuators and robots with an ultrathin form factor using a heat press and a...

Platelet-rich emboli are associated with von Willebrand factor levels and have poorer revascularization outcomes.

BACKGROUND AND AIMS: Platelets and von Willebrand factor (vWF) are key factors in thrombosis and thus are likely key components of acute ischemic stro...

Simultaneous quantification of ticagrelor and its active metabolite, AR-C124910XX, in human plasma by liquid chromatography-tandem mass spectrometry: Applications in steady-state pharmacokinetics in patients.

A sensitive and simple liquid chromatography-tandem mass spectrometry method was developed and validated for the simultaneous quantification of ticagr...

Using Artificial Intelligence to Manage Thrombosis Research, Diagnosis, and Clinical Management.

Thrombosis development in either arterial or venous system remains a major cause of death and disability worldwide. This poorly controlled in vivo clo...

Deep Learning in Personalization of Cardiovascular Stents.

Deep learning (DL) application has demonstrated its enormous potential in accomplishing biomedical tasks, such as vessel segmentation, brain visualiza...

Multi-Objective Optimization for Personalized Prediction of Venous Thromboembolism in Ovarian Cancer Patients.

Thrombotic events are one of the leading causes of mortality and morbidity related to cancer, with ovarian cancer having one of the highest incidence ...

Multicenter experience with photoselective vaporization of the prostate on men taking novel oral anticoagulants.

OBJECTIVE: Photoselective vaporization of the prostate (PVP) is a widely performed surgical procedure for benign prostatic obstruction. This approach ...

Reaffirmation of the importance of follow-up ultrasound studies in patients with high D-dimers and clinical suspicion of vein thrombosis.

BACKGROUND: Venous thromboembolism is a common disease seen in the emergency department and a cause of high morbidity and mortality, constituting a ma...

A Diagnostic Prediction Model of Acute Symptomatic Portal Vein Thrombosis.

BACKGROUND: The aim of this study was to develop a diagnostic prediction model to improve identification of acute symptomatic portal vein thrombosis (...

An artificial intelligence-based clinical decision support system for large kidney stone treatment.

A decision support system (DSS) was developed to predict postoperative outcome of a kidney stone treatment procedure, particularly percutaneous nephro...