Pediatrics

Latest AI and machine learning research in pediatrics for healthcare professionals.

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Claustrum volume in humans – lifespan trajectory and effect of age, hemisphere, and sex

The human claustrum is a bilateral, thin, irregularly shaped gray matter structure located between t...

Single-cell proteomics of pancreatic islet cells reveals type 1 diabetes and donor-specific features

Type 1 diabetes mellitus (T1DM) is the most common severe chronic disease in children and adolescent...

AlveolEye: Rapid and precise lung morphometry guided by computer vision

Rigorous and reproducible evaluation of lung tissue under different conditions is necessary to inter...

Cross-Species Morphology Learning Enables Nucleic Acid-Independent Detection of Live Mutant Blood Cells

In hematology/oncology clinics, molecular diagnostics based on nucleic acid sequencing or hybridizat...

peleke-1: A Suite of Protein Language Models Fine-Tuned for Targeted Antibody Sequence Generation

The discovery of therapeutic antibodies is a traditionally arduous process. Today, the lab-based pro...

Auditory Working Memory in Adolescents with Specific Learning Disorders

Specific Learning Disorders (SLD), including dyslexia, dyscalculia, and dysgraphia, are associated w...

A study on edge devices for image classification of the Tasmanian devil (Sarcophilus harrisii) for vaccine delivery

A target-specific bait dispenser is required for oral bait vaccination of the endangered Tasmanian d...

Deep learning the dynamic regulatory sequence code of cardiac organoid differentiation

Defining the temporal gene regulatory programs that drive human organogenesis is essential for under...

Deep Learning of Brain-Behavior Dimensions Identifies Transdiagnostic Biotypes in Youth with ADHD and Anxiety Disorders

Attention-deficit/hyperactivity disorder and anxiety disorders are highly prevalent in youth and are...

Iron Deficiency Impairs Mitochondrial Energetics and Early Axonal Growth and Branching in Developing Hippocampal Neurons

Each stage of neuronal development (i.e., proliferation, differentiation, migration, neurite outgrow...

ADHD Medications and Preadolescent Brain Structure: Patterns of Cortical Attenuation from the ABCD Study

Attention-deficit/hyperactivity disorder (ADHD) is the most common neurodevelopmental disorder in th...

STODE: A Deep Generative Framework for Continuous Spatiotemporal Dynamics in Spatial Transcriptomics

Spatial transcriptomics offers detailed molecular insights but struggles to capture continuous tissu...

Lab-in-the-loop therapeutic antibody design with deep learning

Therapeutic antibody design is a complex multi-property optimization problem with substantial promis...

Iterative immunogen optimization to focus immune responses on a conserved, subdominant viral epitope

Designing effective vaccination strategies against genetically diverse viruses, such as HIV or influ...

Multivariate environmental exposures are reflected in whole-brain functional connectivity and cognition in youth

Each individual’s complex, multidimensional environment, known as their “exposome”, plays an essenti...

The Macroevolution of Filamentation Morphology Across the Saccharomycotina Yeast Subphylum

Saccharomycotina yeasts are a highly diverse and widely distributed subphylum of ascomycete fungi th...

Dysregulated Microglial Synaptic Engulfment in Diffuse Midline Glioma

Diffuse midline glioma (DMG) is a near-universally lethal form of pediatric high-grade glioma, drive...

A comprehensive bulk and single-cell transcriptional atlas of pediatric leukemias

Advancements in understanding the molecular factors driving pediatric leukemias have led to an ever-...

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