Pediatrics

Latest AI and machine learning research in pediatrics for healthcare professionals.

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Predictive metabolomics to decipher plant eco-evolutive tendencies and physiological traits

Plant ecological and evolutionary strategies are shaped by interactions between phylogenetic history and environmental constraints, resulting in leaf and stomatal traits. However, traditional trait-based and phylogenetic approaches often fail to fully explain biochemical mechanisms underlying ecological strategies, particularly for leaf and stomatal traits. Plant metabolomes integrate genetic, phy...

Asymmetric neural dynamics of visuospatial attention in autism spectrum disorder

Background: Selective attention enables the prioritization of behaviorally relevant information in complex sensory environments. Despite substantial evidence for altered attention in autism spectrum disorder (ASD), the neurophysiological mechanisms underlying these differences remain poorly understood. Methods: Here, we integrate high-density electroencephalography (EEG), pupillometry, and behavio...

Multi-omic data fusion reveals the in vivo enzyme kinetics of Vibrio natriegens at the genome-scale

Vibrio natriegens is a halophilic, Gram-negative marine bacterium that is increasingly used in metabolic engineering applications due to its fast grow...

Distinct associations between multimodal brain measures and psychopathology domains predict adolescent functioning

Adolescent psychopathology is partly rooted in measurable disruptions across key neural networks, yet the field still lacks an integrated, multimodal ...

Automated assessment of neonatal internal capsule maturation on T2-weighted MRI across 7T and 3T

Motivation: Quantitative assessment of neonatal internal capsule (IC) maturation remains largely reliant on qual- itative visual evaluation, limiting ...

Rationale and Design of an Artificial Intelligence Model for Diastolic Heart Failure (AID- HF): A Canadian Cardiomyopathy Collaborative (C3) Study

Diastolic heart failure (HF) in primary cardiomyopathy is under-recognized and often diagnosed late, particularly in children. While recent studies ha...

Identification of Heterogeneous Cortical Thickness Patterns Associated with Prenatal Gestational Diabetes Exposure: A SuStaIn-Based Subtyping Study

Importance: Prenatal exposure to gestational diabetes mellitus (GDM) has been associated with adverse metabolic, neurodevelopmental, and psychiatric o...

Breath volatile profiling reveals a diagnostic signature of MASLD in children

Background & Aims: Metabolic Dysfunction Associated Steatotic Liver Disease (MASLD) is the leading cause of chronic liver disease in children. However...

Protracted prediction: Neurodevelopment of reward processing in the adolescent cerebellum.

Adolescence is characterized by heightened reward sensitivity, novelty seeking, and risky decision-making. Prevailing neurodevelopmental frameworks ty...

Evolutionary transfer learning enables organism-wide inference of mammalian enhancer landscapes

Understanding and modeling how a single human genome concurrently encodes gene regulatory programs for thousands of cell types remains a central chall...

Molecular Characterization of T-Lineage Acute Lymphoblastic Leukemia by an Optimal-Transport Based Multi-Omics Integration Framework

T-lineage acute lymphoblastic leukemia (T-ALL) is an aggressive pediatric malignancy characterized by complex heterogeneity across multiple molecular ...

Machine Learning Estimation of Gestational Age at Delivery Using Linked Mother-Infant Electronic Health Records Across Two Health Systems

Objective This study aimed to train and evaluate supervised machine learning algorithms using electronic health record (EHR) data to accurately estima...

Normative modeling for quantitative brain MRI phenotyping and biomarker discovery for pediatric leukodystrophies

Importance: Leukodystrophies are a heterogeneous group of genetic disorders affecting the white matter of the brain, often presenting with overlapping...

Biomineralized Surface-Enhanced Raman Scattering Nanotags Encode Biomolecular Identity into Machine Learning-Resolvable Plasmonic Fingerprints

Surface-enhanced Raman scattering (SERS) nanotags provide highly sensitive platforms for in vitro diagnostics but often require complex, disease-speci...

Causal Network Mapping of sEEG Identifies Compact Epileptogenic Targets Concordant with Seizure Freedom: Multicenter Validation in 60 Patients

Background and Purpose: Drug resistant epilepsy (DRE) affects approximately 15 million people worldwide, and surgery remains the only curative option....

Predicting Substance Use and Psychotic-Like Experiences in Adolescents

Adolescence is a critical developmental window for the emergence of substance use and psychosis-spectrum symptoms, yet early risk for these outcomes r...

Benchmarking Machine Learning Architectures for Antimicrobial Stewardship in Pediatric ICUs

Antimicrobial stewardship (AMS) is critical in pediatric intensive care units (PICUs), where diagnostic uncertainty often drives broad-spectrum antibi...

May 21 2026 2605.22611v1
Synthetic Data Alone is Enough? Rethinking Data Scarcity in Pediatric Rare Disease Recognition

Children with rare genetic diseases often exhibit distinctive facial phenotypes, yet developing computer vision systems for early diagnosis remains ch...

May 21 2026 2605.22767v1
DeepBioGS: a hybrid framework for integrating crop growth modelling with genomic prediction through neural networks

Ensuring global food security under rapid climate change demands accelerated genetic gain and breeding strategies that address complex Genotype-by-Env...

Synaptic pruning, myelination and the emergence of psychiatric disorders in late adolescence

Adolescence is an important developmental period during which there are diverse changes in the brain and behavior. Goal-directed behaviors and the com...

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