Latest AI and machine learning research in pediatrics for healthcare professionals.
Progress at the intersection of artificial intelligence and pediatric neuroimaging necessitates large, heterogeneous datasets to generate robust and generalizable models. Retrospective analysis of clinical brain magnetic resonance imaging (MRI) scans offers a promising avenue to augment prospective research datasets, leveraging the extensive repositories of scans routinely acquired by hospital sys...
All physiological processes fundamentally rely on continuous cellular cross-talk to maintain organization and ensure proper function. Among the various modes of cellular communication, ligand-mediated chemical signaling, in which a ligand is secreted by one cell, diffuses through the extracellular environment, and binds to a receptor on another (or the same) cell to elicit a downstream response, i...
Cognitive flexibility, the ability to adapt behavior in response to changing contingencies, is a key component of adaptive decision-making and is impa...
Manual extraction of high-fidelity gene-disease-phenotype information from human genetics literature is a labor-intensive task that requires trained h...
Type 1 diabetes (T1D) is associated with microbial dysbiosis. While most research has focused on the gut microbiome, limited data address the role of ...
Exposure to humidifier disinfectants has been linked to an array of pulmonary disorders and diminished lung functionality particularly reduced Forced ...
Although developmental language delays affect approximately 10% of children in the general population, the neurodevelopmental mechanisms that support ...
Cochlear hair cells are essential for hearing, and their stereocilia bundles are critical for mechanotransduction. However, analyzing the 3D morpholog...
Ecosystems are rapidly degrading. Widely used approaches to monitor ecosystems to manage them effectively are both expensive and time consuming. The r...
The human claustrum is a bilateral, thin, irregularly shaped gray matter structure located between the striatum and insula. While previous research de...
In hematopoietic cell transplant patients, intestinal Candida parapsilosis expansion and translocation cause life-threatening candidemia, yet how comm...
Type 1 diabetes mellitus (T1DM) is the most common severe chronic disease in children and adolescents and requires life-long exogenous insulin treatme...
Rigorous and reproducible evaluation of lung tissue under different conditions is necessary to interpret development, injury, and pharmacologic interv...
In hematology/oncology clinics, molecular diagnostics based on nucleic acid sequencing or hybridization are routinely employed to detect malignancy-as...
The prefrontal cortex (PFC) is one of the last brain regions to fully mature, making it particularly sensitive to drug use early in life. Both human a...
The discovery of therapeutic antibodies is a traditionally arduous process. Today, the lab-based process of antibody discovery consists of several tim...
Specific Learning Disorders (SLD), including dyslexia, dyscalculia, and dysgraphia, are associated with deficits in executive functions such as audito...
Early detection of neuromuscular disorders is a major clinical challenge, with most diagnoses only occurring after considerable motor neuron degenerat...
A target-specific bait dispenser is required for oral bait vaccination of the endangered Tasmanian devil (Sarcophilus harrisii) against the deadly dev...
Defining the temporal gene regulatory programs that drive human organogenesis is essential for understanding the origins of congenital disease. We com...