Obstetrics & Gynecology

Pregnancy

Latest AI and machine learning research in pregnancy for healthcare professionals.

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Transformer-based multidimensional feature fusion for accurate prediction of lipid nanoparticles transfection efficiency.

RNA-based technologies have demonstrated significant potential for diverse applications, ranging from vaccination to gene editing. However, their widespread adoption is limited by the critical challenge of efficient delivery. Lipid nanoparticles (LNPs) have emerged as a widely utilized RNA delivery system, yet their formulation design and optimization primarily rely on empirical trial-and-error, w...

Mar 1 2026 41766648

Evaluation of the Effectiveness of an AI-assisted, Dual-Template Workflow in Improving the Accuracy of Tooth Autotransplantation.

OBJECTIVE: To test whether an AI-assisted, dual-template workflow improves plan-delivery accuracy in tooth autotransplantation versus a replica-only freehand approach. METHODS: Twenty-four consecutive cases were assigned to a guided workflow (n = 12) or freehand (n = 12). In the guided group, AI-driven CBCT segmentation informed a socket-preparation guide, a socket-margin guide, and a printed dono...

Mar 1 2026 41771190
Learning 3-D Ultrasound Segmentation under Extreme Label Deficiency.

OBJECTIVE: 3-D ultrasound imaging has shown great promise in clinical diagnosis by offering comprehensive volumetric assessment of organs and anatomic...

Mar 1 2026 41771726
Exosome-enabled bone defect repair: mechanistic foundations, bioengineered delivery, and artificial intelligence-driven translation.

Bone defects remain a substantial clinical burden. Exosomes have been extensively investigated as cell-free therapeutic candidates, exhibiting favorab...

Mar 1 2026 41764501
Advanced Drug Delivery Strategies for Overcoming Biological Barriers: Tumor Microenvironment and Blood-Brain Barrier.

Therapeutic efficacy for malignancies and neurological disorders is fundamentally restricted by biological barriers, particularly the complex tumor mi...

Mar 1 2026 41764714
Diagnostic and Technological Advances in Magnetic Resonance (Focusing on Imaging Technique and the Gadolinium-Based Contrast Media), Computed Tomography (Focusing on Photon Counting CT), and Ultrasound-State of the Art.

Magnetic resonance continues to evolve and advance as a critical imaging modality for disease diagnosis and monitoring. Hardware and software advances...

Mar 1 2026 40485609
Versatile Backdoor Attack With Visible, Semantic, Sample-Specific and Compatible Triggers.

Deep neural networks (DNNs) can be manipulated to exhibit specific behaviors when exposed to specific trigger patterns, without affecting their perfor...

Mar 1 2026 41364567
Maternal and Pediatric Precision in Therapeutic Knowledge Portal (MPRINT-KP): Landscape Analysis of Pharmacology Research in Maternal and Pediatric Patient Populations.

Pregnant women and children have been underrepresented in clinical studies due to ethical concerns and perceived vulnerabilities. This resulted in a s...

Mar 1 2026 41730795
Modeling Polymeric Drug Release: The Emerging Role of Machine Learning.

Polymeric drug formulations have significantly improved the safety, efficacy, and clinical impact of many therapies. A persistent challenge for formul...

Mar 1 2026 41771757
Fetal and neonatal alloimmune thrombocytopenia (FNAIT): From reactive transfusion to proactive prevention.

Fetal and neonatal alloimmune thrombocytopenia (FNAIT) is a major cause of severe thrombocytopenia, intracranial hemorrhage, and long-term neurologica...

Feb 28 2026 41791326
Addressing multiple pregnancies in in vitro fertilization-embryo transfer: Current status, challenges, and solutions.

With the rising global incidence of infertility and the growing proportion of infants conceived via in vitro fertilization-embryo transfer (IVF-ET), m...

Feb 28 2026 41761862
Nanozymes for Liver Disease Therapy: Advances in Catalytic Activity, Targeting Strategies, and Clinical Translation.

Natural and artificial enzymes have emerged as promising candidates for biomedical applications, possessing the potential to address redox imbalances ...

Feb 28 2026 41762712
Single-nucleus multi-omics dissection of dysregulated trophoblast development and disrupted immune microenvironment in complete hydatidiform moles.

Hydatidiform mole (HM) is driven by aberrant trophoblast proliferation, disrupting embryonic development and leading to pregnancy loss with increased ...

Feb 27 2026 41772202
Polysaccharide-functionalized gold, silver, and iron oxide nanoparticles for siRNA delivery: The role of artificial intelligence in design and optimization.

Polysaccharide-functionalized metallic nanoparticles (MFNPs), including gold (Au), silver (Ag), and iron oxide (Fe3O4), have emerged as promising nano...

Feb 27 2026 41809385
Machine Learning-Informed Nano Co-Assembly Inhibits Fibroblast Activation Protein and Improves Drug Delivery in Fibrotic Tissue.

Nanoparticle-based drug delivery faces persistent challenges, including complex fabrication processes and limited lesional accumulation. Here we intro...

Feb 27 2026 41757658
Efficient Serum Metabolic Fingerprints for Ectopic Pregnancy Diagnosis and Rupture Risk Prediction.

Ectopic pregnancy (EP) is a leading cause of maternal morbidity and mortality in early pregnancy. Current diagnostic approaches, which rely on ultraso...

Feb 27 2026 41757682
Liquid-Sequencer: A Lightweight Liquid Neural Network for Real-Time Fetal Congenital Heart Disease Diagnosis.

Congenital heart disease (CHD) is the leading cause of neonatal mortality worldwide, making early and accurate diagnosis crucial. In resource-constrai...

Feb 27 2026 41758854
Impact of quality routine health data utilisation on health service delivery outcomes in low-income and middle-income countries: a systematic review protocol.

BACKGROUND: Evidence-based decision-making in healthcare relies heavily on routine health information. However, in many low-income and middle-income c...

Feb 27 2026 41760145
Clinical Grading of Artificial Intelligence-Based 3D Fetal Brain Segmentations: A Cross-Vendor Evaluation of Deep Learning in Fetal Neuroimaging.

OBJECTIVE: To evaluate the performance of automated (sub)cortical fetal brain segmentation methods on a novel 3D ultrasound dataset acquired from a di...

Feb 27 2026 41761049
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