Primary Care

Preventive Care

Latest AI and machine learning research in preventive care for healthcare professionals.

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Overcoming gastrointestinal mucosal barriers: Mechanistic innovations and technical advances in mucosal targeting strategies for animal oral vaccines.

Infectious diseases caused by pathogenic microorganisms (such as Escherichia coli, Avian influenza virus (AIV), Rotavirus, etc.) that primarily invade through mucosal surfaces like the digestive tract and respiratory tract not only severely restrict the development of the livestock and poultry breeding industry, resulting in huge economic losses, but also threaten public health security due to the...

Mar 6 2026 41819733

Assessing the clinical competence of large language models for tobacco use disorder: A multi-domain expert evaluation.

BACKGROUND: Tobacco use disorder (TUD) remains the leading preventable cause of death globally, yet fewer than one-third of users receive guideline-concordant care due to workforce shortages and training gaps. Emerging artificial intelligence (AI) systems, particularly large language models (LLMs), may help expand access to evidence-based cessation support, but their clinical competence remains in...

Mar 6 2026 41789824
Machine learning-based prediction of sudden cardiac death in the general population using electronic health record data.

AIMS: The vast majority of sudden cardiac death (SCD) cases occur in the general population with few known risk factors instead of just patients alrea...

Mar 6 2026 41790031
Cross-Cultural Differences in Public Discourse on COVID-19 Vaccination in the United States and South Korea: Cross-Sectional Analysis Using Natural Language Processing.

BACKGROUND: The COVID-19 vaccine was introduced as a crucial tool to combat the pandemic. However, concerns about its effectiveness, side effects, and...

Mar 5 2026 41785455
A copula based supervised filter for feature selection in machine learning driven diabetes risk prediction.

Effective feature selection is critical for building robust and interpretable predictive models, particularly in medical applications where identifyin...

Mar 5 2026 41786845
Digital Stethoscope-Derived Single-Lead Electrocardiogram and Artificial Intelligence to Detect Low Ejection Fraction: A Multicenter Observational Study.

OBJECTIVES: Identifying patients likely to benefit from an echocardiogram before surgery is prudent in resource-limited settings. Recently, artificial...

Mar 4 2026 41925404
Artificial Intelligence in Mammography Screening: A Narrative Review of Progress, Pitfalls, and Potential.

Artificial intelligence (AI), particularly deep learning (DL), is transforming the field of medical imaging and holds substantial promise for advancin...

Mar 4 2026 41782331
Machine learning to risk stratify individuals for undiagnosed atrial fibrillation at scale using population-wide electronic health records.

AIMS: Electronic health records (EHR) can be used to target atrial fibrillation (AF) screening. We evaluated the performance of risk prediction models...

Mar 4 2026 41776766
Exploring the impact of reimbursement ratios on willingness to vaccinate: A mixed-effects modeling approach using panel data.

Vaccination remains one of the most cost-effective methods for disease prevention. However, utilization of self-paid vaccines, including EV71, varicel...

Mar 3 2026 41774860
Host-focused immunity, metabolism, and diagnostic innovation for precision control of tuberculosis globally.

Tuberculosis (TB), caused by Mycobacterium tuberculosis (MTB), remains one of the deadliest infectious diseases worldwide. Despite advances in treatme...

Mar 3 2026 41786285
AI-based BRAIx risk score for the intermediate-term prediction of breast cancer: a population cohort study.

BACKGROUND: Artificial intelligence (AI)-based algorithms are being implemented in breast screening to detect breast cancers on mammographic images. W...

Mar 3 2026 41781282
A Multiomic Liquid Biopsy for the Earlier Detection of Colorectal Cancer.

UNLABELLED: Timely diagnosis and intervention in colorectal cancer are critical to improving patient outcomes and limiting disease progression. Screen...

Mar 3 2026 41431387
Evaluation of a Community-Based AI-Assisted Visual Impairment Screening Model for Performance, Operational Efficiency, Acceptability, Feasibility, and Costs: Protocol for a 2-Arm Pragmatic Randomized Controlled Trial.

BACKGROUND: Visual impairment (VI) affects more than 600 million people globally and significantly reduces quality of life. In Singapore, 20% of adult...

Mar 2 2026 41773693
Transformer-based multidimensional feature fusion for accurate prediction of lipid nanoparticles transfection efficiency.

RNA-based technologies have demonstrated significant potential for diverse applications, ranging from vaccination to gene editing. However, their wide...

Mar 1 2026 41766648
Fetal and neonatal alloimmune thrombocytopenia (FNAIT): From reactive transfusion to proactive prevention.

Fetal and neonatal alloimmune thrombocytopenia (FNAIT) is a major cause of severe thrombocytopenia, intracranial hemorrhage, and long-term neurologica...

Feb 28 2026 41791326
A Preliminary Report: Screening Idiopathic Scoliosis (IS) With a Smartphone Application.

INTRODUCTION: Idiopathic scoliosis (IS) is a 3-dimensional spinal deformity that affects ∼3.1% of the population. Current strategies for IS screening ...

Feb 27 2026 41747211
Predicting Nocturnal Hypertension in CKD Through Table-Value Diffusion Model.

BACKGROUND: Ambulatory blood pressure monitoring is indispensable for diagnosing nocturnal hypertension (NH) among patients with chronic kidney diseas...

Feb 26 2026 41744090
New treatments to rabies virus infections.

Rabies disease is the deadliest of all virus infections. Till now, vaccination is the most effective and reliable treatment for controlling rabies. Ho...

Feb 26 2026 41759787
Protocol for a pragmatic trial comparing navigator and automated virtual interventions for guaranteeing adherence to fecal immunochemical testing (NAVIGATE-FIT).

BACKGROUND: Fecal immunochemical testing (FIT) - a non-invasive colorectal cancer (CRC) screening method offers an opportunity to bridge CRC screening...

Feb 26 2026 41800147
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