Latest AI and machine learning research in preventive care for healthcare professionals.
ConspectusViral proteases are essential enzymes required for viral replication and assembly, making them prime antiviral drug targets. However, under the selective pressure of protease inhibitors, viruses can acquire mutations that reduce drug binding efficacy, posing significant challenges in both chronic infections (e.g., HIV, HCV) and acute infections like COVID-19, where mutations in the SARS-...
Diabetic retinopathy (DR) is a leading cause of preventable blindness, and the growing global burden of diabetes is placing increasing pressure on ophthalmic services. Artificial intelligence (AI)-based retinal image analysis offers a promising strategy to scale up DR screening while reducing reliance on specialist graders. We assessed the performance of an AI-based DR screening system implemented...
BACKGROUND: Dental caries is the most prevalent chronic, noncommunicable condition affecting individuals of all ages and socio-economic status. The re...
AIMS: Valvular heart disease (VHD) can affect more than one in two adults over 65 yet remains underdiagnosed due to the limitations of traditional aus...
Type 2 Diabetes (T2D) remains a major global health issue, driven by sedentary lifestyles and aging populations, emphasizing the urgent need for preci...
INTRODUCTION AND AIMS: To develop a multimodal deep learning model for dental caries screening in children by integrating intraoral photographs and qu...
OBJECTIVE: Despite advances in mammography screening, some cancers remain undetected, prompting the evaluation of artificial intelligence (AI) as an i...
Healthcare decisions at the beginning and end of life pose enduring moral challenges that are increasingly intensified by the integration of artificia...
BACKGROUND: Artificial intelligence (AI) applications in endoscopy, particularly computer-aided detection (CADe), have shown consistent benefit in ran...
BACKGROUND: As Singapore adopts a population health approach under Healthier Singapore (Healthier SG), optimizing healthcare resources is crucial. We ...
BACKGROUND: Influenza vaccination is an effective measure for reducing the risk of severe influenza infection. However, the task of achieving adequate...
Breast cancer is the most common non-skin cancer and the second leading cause of cancer death in U.S. women. Early detection and timely intervention a...
BACKGROUND: Computer aided detection (CADe) colonoscopy has been shown in randomized controlled trials to improve detection of adenomatous colorectal ...
BACKGROUND: Artificial intelligence (AI) is being rapidly integrated into oncologic care, yet little is known about how patients perceive these applic...
Ionizable lipids are fundamental to the efficacy of lipid nanoparticles (LNPs) in pivotal areas including mRNA vaccines. Their development, however, i...
BACKGROUND: Hepatitis B (HBV) is a chronic viral infection that can lead to cirrhosis, liver failure, and liver cancer, and has a profound impact on t...
The objective of this study was to explore the lipid metabolic changes in the active thyroid-associated ophthalmopathy (TAO) through tear lipidomics a...
AIMS: Early aortic stenosis (AS) detection remains challenging, with many patients presenting late when left ventricular dysfunction may be irreversib...
BACKGROUND: Early identification of individuals at elevated cardiovascular risk using routine health examination data is essential for preventive card...
BACKGROUND: Mobile health (mHealth), leveraging mobile devices for health measurement and promotion, is rapidly growing. Smartphone cameras can perfor...